AIM:
Study of dyslipidemia in non-diabetic first degree relatives (F.D.R.) of type 2 diabetes mellitus patients.

MATERIALS AND METHODS:
Forty type –2 diabetes mellitus with forty numbers of their FDR were included in the study. Secondary causes of dyslipidemia were excluded in both groups by history taking, clinical examinations and appropriate laboratory tests. Fasting lipid profile comprising of serum cholesterol, triglyceride and HDL-C were done in automatic analyzer and VLDL-C, LDL-C values were calculated out by using Friedwald equation.

OBSERVATION:
Mean cholesterol, triglyceride and LDL-C values were below normal (i.e. cholesterol < 200mg/dl, triglyceride <150mg/dl and LDL-C < 130 mg/dl) but diabetics showed higher values than FDR and 15% of FDR were having HDL-C values below normal (i.e. <40mg/dl in males and <45 mg/dl in females) 22.5% diabetics and 30% FDR were having cholesterol /HDL C-Ratio > 5, while LDL-C/HDL – C ratio > 3.5 were found in 12.5% of diabetics and 20% of FDR (Atherogenic ratio).

CONCLUSION:
F.D.R. of type 2 diabetes mellitus patients showed very high incidence of low HDL-C level, perhaps prevalence of more of insulin resistance in them, thus predisposing them to atherogenic profile even if they are normoglycemic and this makes a need of creating awareness in them.