Aims and Objective:
Dyslipidemia is associated with 50% of all diabetic people and contributes to substantial increased risk (3-4 fold) of premature, extensive and accelerated atherosclerosis leading to CAD, PVD and MI etc. It remains silent in majority of patients with diabetes. This peculiarity makes CAD in diabetes the single most important cause of premature mortality accounting for 60-65% of all deaths. The aims of the present study was to determine the pattern of dyslipidemia in patients of CAD with type – 2 DM so as to initiate anti-lipidemic therapy for secondary prevention.

MATERIALS AND METHODS:
We studied 100 cases of type 2 DM with CAD and without CAS admitted to V.S.S. Medical College and Hospital, Burla, Orissa. The mean age group of the study was 30-69 years from both the sexes. The FBS and 2 hour PPBG was done by glucose oxidase method and serum lipid profile was estimated by enzymatic methods and compared to study the pattern of dyslipidemia.

Results:
In the present study dyslipidemia was found in 92% of diabetic patients with LDL hyperlipoproteinemia in 76% (LDL > 100mg%)HDL dydlipidemia in 64% (HDL < 40 mg%), hypertriglyceridemia in 925 (TG > 150 mg%) and hypercholesterolemia (56%) (> 200,g%). The lipid profile was significantly altered in patients with coronary artery disease compared to patients without coronary artery diseases.

Conclusion:
The major concern in the present study highlights the high percentage of LDL and TG dydlipidemia. However TC and HDL levels were of less significance. In the present study more than 90% of patients were smokers and alcoholics, LDL dyslipidemia is more significant from prognostic and therapeutic point of view, hence pharmacotherapy in the form of statins and TG dyslipidemia can be brought down by blood glucose control itself. Glycemic control should be the first priority followed by fibric acid derivatives or high dose statins.