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Menstruation Problems In Female
Amenorrhea
The absence of menstrual period in women is called Amenorrhea. It is of two types.

1. Primary Amenorrhea
The failure of menses in women even after turning up to 16 years of age, is called as primary amenorrhea.

Causes
• Chromosomal or genetic abnormalities and mainly Turner syndrome. • Uterus structural defects. • Uterus infection. • Cystic fibrosis. • Cushing’s syndrome. • Imbalance in hormones. • Mainly adrenal gland problems. • Intake of Medicines for Cancer disease treatment and anti-depressive.

2. Secondary Amenorrhea
The stop of regular and normal menstrual cycles after the pregnancy for 3 months or more is called as Secondary amenorrhea.

Causes
• Pregnancy. • Breastfeeding and menopause. • Pituitary gland. • Thyroid problems. • Intake of contraception medicines and few antidepressants medicines. • PCOD (Polycystic Ovary Disease). • Strenuous exercise. • Uterus related operations.

Oligomenorrhea
It occurs in women of childbearing age. Some variation in menstruation is normal. A woman who regularly goes over 35 to 40 days without menstruating may be diagnosed with Oligomenorrhea. Light or infrequent menstrual periods less than 35 to 40 milli is also called as Oligomenorrhea.

Causes
• PCOD. • Formation of pituitary glands tumours. • The cause of Oligomenorrhea is mainly seen during the end of menstruation period.

Metrorrhagia
The occurrence of menses period between two menstruation cycles is called as metrorrhagia. Mainly during the release of egg this metrorrhagia problem is seen.

Causes
• Adenomas. • Endometriosis. • Ectopic pregnancy. • Hormones imbalance. • Intake of contraception medicines. • Usage of contraception equipment (IUD).

Menorrhagia
The abnormally heavy bleeding at menstruation for more than normal 5 days is called as Menorrhagia.

Causes
• Uterine fibroids. • PCOD problems. • Thyroid problems. • Endometriosis. • Cancer in the Uterus.

Dysmenorrhea
The Painful menstruation, typically involving abdominal cramps that effect daily activities of women is called as Dysmenorrhea. It is mainly seen either before the few days of the menstruation periods or during the first three days of menstruation period.

Causes
• Endometriosis. • Tumors in hysterectomy. • Ovarian water cysts. • Hormones imbalance.

GENERAL SYMPTOMS OF THE DISEASE
Menopausal Symptoms Peri-menopausal and menopausal symptoms can appear at any time of life, although usually their onset begins in a woman’s late forties or early fifties. Menopausal symptoms are clearly delineated in most women, and consist of one or more of the following problems - some patients even present with all of the below symptoms. • Anemia, Weakness,* Feeling of intense heat in your body on some occasions • Profuse sweating at night • Excessive falling of hair, • Irregular menstrual periods with excessive or scanty bleeding, • Burning and increased frequency of micturation, • Vaginal dryness and itching • Joint pain, • Edema, • Irritable nature, • Sleeplessness Lassitude.

INDICATION
• Leucorrhoea • Dysmenorrhea • Amenorrhoea • Metrorrhagia • Oligomenorrhea • Menorrhagia • Low Back Pain

Benefits Of Gyneza
• it is helpful in dealing with health of female reproductive system • Increase fertility in females • Releases stress • Enhances immunity which helps to optimize overall health • Helpful in leucorrhoea • Increase Stamina • scanty menstruation • menopause

COMPOSITION
Ashoka, Dashmoola, Lodhra, Guduchi, Punarnava, Shatavari, Musta, Anantmoola, Triphala, Jatamansi, Pippalimoola, Trikatu, Aal, Methika, Ashwagandha

Ashoka
Ashoka bark is considered as the uterine tonic and uterine sedative as it helps in reducing the pain and bleeding during periods.

Dashmoola
These magic herbs and spices soothe the digestive process. It is used in the treatment of anemia, .

Lodhra
• Lodhra is considered useful in managing female disorders such as leucorrhea (excessive vaginal discharge) which is caused by vaginal infections as it has antimicrobial and anti-inflammatory properties. • It is a well known coagulant (coagulation is a process by which the blood forms clots to block and then heal a wound/cut to stop the bleeding). It is therefore used in the treatment of bleeding disorders . Lodhra is especially helpful in inflammation of the uterus.

Punarnava
Thus traditional herbs are used in gynecological disorders Ovulation problems due to polycystic ovarian syndrome.

Shatavari
Shatavari might be beneficial in the management of uterine bleeding or heavy menstrual bleeding. It acts as a primary uterine tonic. It helps to balance and strengthen the menstrual system.

Musta
Musta is great for your digestive and urinary system. Motha (nutgrass) in Ayurveda used to treat various female disorders.

Anantmool
It is used for the management of many gynecological problems in females such as menorrhagia.

Triphala
Triphala is a herbal medicine that has been widely used for treating a variety of ailments. This study aims to systematically analyze the antitumor effects of Triphala on gynecological cancers.

Jatamansi
It is recommended for gynecological problems especially in frequent abortions.

Pippalimoola
It is used to treat semen defects and gynecological problems.

Trikatu
Trikatu gives strength to the reproductive system, used to treat obesity as it keeps a check on food cravings, works as anti-inflammatory and analgesic due to the presence of Sunthi in it which works as Vata Shamaka, that is, it balances the aggravated Vata Dosha which is mainly responsible for all kind of pains.

Trikatu
Trikatu gives strength to the reproductive system, used to treat obesity as it keeps a check on food cravings, works as anti-inflammatory and analgesic due to the presence of Sunthi in it which works as Vata Shamaka, that is, it balances the aggravated Vata Dosha which is mainly responsible for all kind of pains.

Aal (Noni)
Noni (Morinda citrifolia) has been used for many years as an anti-inflammatory agent. & gynecological problem that a?ects adolescents and is reported to have many beneficial properties

Methika
Reduces pain in women with painful menstrual periods.

Ashwagandha
Ashwagandha is considered one ... as a blood tonic, especially in gynecological disorders including anemia.

Dosage
2 teaspoon diluted with 100ml water twice a day for 15 days to 3 months.

Research Objective
The Study indicates that research provides chemo preventive effects
Significant reduction in cancerous cells
Indicative suppression of growth of tumor
Quantifying and analyzing DNA damage in individual cells

Abstract
PHPC Compound is the patent and proprietary medicine developed by Benmoon Pharma Research Pvt Ltd., Ahmedabad. The entire study was planned to do evaluation of efficacy and safety of PHPC Compound in experimental animal’s models. First it was screened in-vitro using breast cancer cell line using MTT assay method, wherein it has shown significant reduction in viable cancerous cells.
After promising result in in-vitro study, safety was checked using Acute toxicity study (OECD 425), wherein it was found safe till the dose of 2000-5000mg/kg, orally.

Further, for long term usage of this formulation, its sub-chronic (90 days) oral toxicity study was done (AYUSH & OECD 408 guideline) in rats and guinea pigs, wherein it shows no significant toxic sign, symptoms and in histology too. To check whether it retards toxic effects against chemotherapeutic agents induced toxicity, it was evaluated against 5-FU model, wherein also it has shown chemo-preventive activity.

To check its effectiveness against breast cancer, it was further screened against DMBA-induced cancer model, wherein also it has shown significant reduction in occurrence of tumor, reduction in tumor size and volume. DMBA induced breast cancer by DNA mutation and increasing free radicals level. The treatment of PHPC Compound reduces free radical levels as evident by significant increase in SOD and Catalase level. Further, it reduces serum level of SGOT and SGPT level, which usually get secreted during tissue damage.
Further to check the effectiveness of the PHPC Compound on DNA damage in individual cells of cancer cell line. In the present study, in 5-FU (5.0μg/ml ) treated cell line, there was reduction in % Head and increase in % Tail, which indicates DNA damage in L929 and MCF-7 cell line. Wherein in case of Test drug (20, 40 and 60 μg /ml) groups, there was significant increase in % Head and decrease in % Tail, which indicates that test drug provides chemo preventive effects. In brief, PHPC Compound has shown promising level of safety and efficacy in experimental animal models.

Introduction
The purpose of the research study on cancer is to develop safe and effective methods to prevent, detect, diagnose, treat, and, ultimately, cure the collections of diseases we call cancer. Ideas for new cancer research studies are often inspired by findings from earlier research, research on other cancers, and even findings from research done on other diseases, such as diabetes or immune disorders. Its aim is to reduce the number of deaths from cancer.
The research reports that covers cytotoxicity study evaluated for cytotoxicity against human adenocarcinoma cell for performing Anti - Cancer Activity effect on cellular DNA damage with his research called PHPC Compound has shown significant reduction in occurrence of tumor, reduction in tumor size and volume, having conducting clinical researches, investigating methods of prevention, diagnosis & treatment studies for several years . The results revealed that the formulation showed significant cytotoxicity on cell line. Overall, the cell growth inhibition by the PHPC observed in this study synergistic response rates. In brief, PHPC Compound has showing promising level of results in experimental models. To check the effect of PHPC Compound on cellular damage against normal cell line and breast cancer cell line using commet assay method. Cell count, Splitting of cells, ratio analysis of the cells and cells viability following the procedure mentioned allow the cell to grow and divided into groups.

To check the effect of formulation PHPC Compound on cellular DNA damage against normal celline and against breast cancer cell line MCF 7 using single cell gel electrophoresis technique commet assay. The scope covers comet assay of given test samples as per in house method. Evaluation of DNA damage for visualization of DNA damange, observations are made of SyBR-stained DNA using a 40x objective on a fluoroscent microscope.
Women breast cancer is the most important cause of mortality in the world. Now a day, some cytotoxic agents are used for its treatment including 5- flurouracil, doxorubicin, daunorubicin, bleomycin, and cisplastin. However, they are costly and known to induce several side effects such as myelosuppression, anemia, and most importantly the generation of cellular resistance. For this, it is important to find alternative therapies or drugs to overcome these drawbacks. Therefore in the present study,the polyherbal formulation screened for its anticancer activity using MCF-7 cell lines. The formulation PHPC Compound was subjected to cell proliferation assay by MTT. The results revealed that the formulation showed significant cytotoxicity on MCF-7 cell line. Overall, the cell growth inhibition by the polyherbal formulation observed in this study synergistic response rates.

Summary of Findings
Mammary tumors were successfully induced by oral administration. PHPC Compound produced significant anti-cancer activity, which was evident by significant reduction in incidence of solid tumor in PHPC Compound treated group. This was clearly indicated by means of results of tumor as compared to diseases control group and histopathology of mammary gland. PHPC Compound significantly increased the level of antioxidant enzymes like SOD and catalase, which were reduced in case of diseased controlled groups. This indicates chemo-protective effect of PHPC Compound.

Dr. Samrat Jankar is one of the most expert reliable and ethical fistula specialists in Pune. He is a qualified surgical gastroenterologist and colorectal surgeon and had been awarded a gold medal for fellowship in colorectal surgery by the ACRISI (Association of Colon & Rectal Surgeons of India) board. Furthermore, he has been an international faculty member in this field. Recently, he has been awarded the First Prize for the best video presentation at FISTULACON 2021 for the LASER LIFT procedure in complex fistula in Ano in an international summit organized by ACRSI. He delivered talks on fistula at many national and international conferences and had a live demonstration of fistula surgery at many conferences. He had trained many surgeons for LASER fistula surgery. Dr. Samrat Janakr had been trained for complex fistula in ano surgery under renowned fistula surgeons Dr. Parvez Sheikh (Mumbai) and Dr. Arun Rajunasakul (Bangkok). He is an expert in many surgical procedures for fistula treatment and also pioneered his own surgical technique PILTEC for complex fistula treatment which has the highest success rate. Dr. Samrat Jankar had successfully Performed more than 5000+ successful Anal Fistula Surgeries.

Fistula (Bhagandar) Treatment in Pune
An anal fistula is a tunnel connecting the skin near the anus to the inside of the bowel (usually the rectum). This means that the inside of the bowel is connected to the outside of the body through an additional opening. An anal fistula often results from a previous or current anal abscess. As many as 50% of people with an abscess get a fistula. However, a fistula can also occur without an abscess.


Fistula in Ano treatment options
Surgery is usually necessary to treat an anal fistula as they usually do not heal by themselves or only with medication. The goal of any surgery for a fistula in ano is to balance between getting rid of the fistula and protecting the anal sphincter muscles, which could cause incontinence if damaged. In fistula treatment in Pune what matters most is recurrence and incontinence, the only expert in fistula surgery will have a clear understanding of it. Looking for the best doctor for fistula in ano treatment in Pune, Dr. Samrat Jankar an Internationally recognized surgeon at KAIZEN Gastro care, Wakad Pune offers holistic treatment for complex fistula with the least recurrence rate & almost zero incontinence rate.


Types of Fistual in Ano
Fistulas are classified by their relationship to parts of the anal sphincter complex (the muscles that allow us to control our stool). They are classified as

Intersphincteric
Transsphincteric
Suprasphincteric
Extrasphincteric.
Intersphincteric is the most common and Extrasphincteric is the least common. These classifications are important in helping the surgeon make treatment decisions

What is Complex Fistula?
The Standards Committee for the American Society of Colon and Rectal Surgeons (ASCRS) divided anal fistula into simple and complex types based on the complexity of fistula, risk of recurrence, and risk of incontinence.

Simple fistula:

Simple fistulas are those that are Intersphincteric or low Transsphincteric involving less than 30% of the external sphincter where the risk of incontinence is low.

Complex fistula:

“Complex� fistulas included those with

More than 30% sphincter muscle involvement
Anterior fistulas in female patients
Recurrent fistulas
Fistula associated with preexisting fecal incontinence, inflammatory bowel disease, or prior radiation.
There are several different procedures. The best option for you will depend on the position of your fistula and whether it’s a single channel or branches off in different directions. Surgery aims to heal the fistula while avoiding damage to the sphincter muscles, the ring of muscles that open and close the anus, which could potentially result in loss of bowel control.

The main options are outlined here:
1. Fistulotomy:
The most common type of surgery for anal fistulas is a fistulotomy. This involves cutting along the whole length of the fistula to open it up so it heals as a flat scar. A fistulotomy is the most effective treatment for many anal fistulas, although it’s usually done in simple fistula where the risk of incontinence is less. This procedure is not suitable in complex fistula in ano in cases where the risk of incontinence is considered too high, sphincter preserving procedures are recommended.

At KAIZEN Gastro Care, Dr. Samrat Jankar Fistula Specialist Surgeon in Pune uses a LASER as an adjunct to Fistulectomy to minimize the risk of damage to the sphincter muscle. Thus, with the added advantage of Laser, the chances of post-operative pain will be negligible.


2. Ligation of the intersphincteric Fistula Tract (LIFT):
The ligation of the intersphincteric fistula tract (LIFT) procedure is a best treatment for fistulas that pass through the anal sphincter muscles, where a fistulotomy would be too risky. This is a Highly efficient procedure with almost no recurrences or incontinence. Dr. Samrat Jankar, a well-known colorectal surgeon in Pune, specializes in complex fistula surgery


Moreover, he is adept in LIFT, an advanced procedure for fistula treatment in Pune. Being well-trained with the LIFT procedure under Dr. Arun Rajunasakul (pioneer of the LIFT procedure, to date, Dr. Jankar has performed more than 1000 modified LASER LIFT procedures with excellent results. Had been awarded the best video award at an international conference for the management of complex fistula.

3. FiLaC ( Fistula-tract Laser Closure):
It is a minimally invasive fistula-in-ano surgery that keeps the sphincter intact. This technique attempts to gently remove the anal fistula by using laser energy. The flexible, all-around radiating fiber-optic probe is inserted into the fistula tract from the outside. Then the laser is slowly withdrawn. The inflammatory tissue is destroyed in a controlled manner and the fistula tract contracts. The anal gland that originally caused the fistula is inactivated


4. VAAFT:

Video-assisted anal fistula treatment (VAAFT) is a new minimally invasive and sphincter-saving endoscopic treatment for complex fistulas. The fistula tract and internal fistula are localized using a fistuloscope inserted through the external opening and under direct vision fistula tract is destroyed from the inside and closure of the internal opening is done by stapling or suturing or cutaneous-mucosal flap.

Advantages

No surgical wounds on the buttocks or perianal region.
The internal opening is precisely located which is important in the treatment of any fistula.
Less chance of damage to the sphincter muscle
Potential drawbacks

The biggest argument against VAAFT is its high rate of recurrence (~30%)
Higher cost of treatment
5. FISTULA PLUG
The fistula plug is a 100% synthetic bio-absorbable scaffold. This plug is placed in the fistula tract. Over time cells from the body migrate into the scaffold and new tissue is generated as the body gradually absorbs the plug material, leaving no permanent material in the body.

Advantages of Fistula Plug

No cutting involved and no operation wound. Therefore it is associated with less pain and faster recovery.
No damage to the sphincter muscle.

Potential Drawbacks

Failures can occur due to the dislodgement of the plug from the fistula tract.
The plug can get infected
Failure of treatment can occur in 25-30% of cases
6. PILTEC: a modification of the LIFT procedure
Dr. Samrat Jankar an internationally recognized fistula surgeon pioneered the LASER procedure named PILTEC having the highest cure with zero incontinence rate. He had demonstrated at many surgical conferences and workshops. He had trained many surgeons in fistula treatment using the PILTEC procedure.

Why does the Fistula recur again and again?
Anal fistula treatment remains a challenge for surgeons owing to its persistence or recurrence. Recurrent anal fistulas after surgery are more difficult to treat as there is even more risk of re-recurrence. Now, the challenge is that, even with the availability of so many techniques, there is a high risk of recurrence of the fistula after surgical intervention depending upon the location of the fistula, the kind of procedure performed, the expertise of the surgeon, extent of disturbing anatomy of the perianal region, unexpected findings, the effect of excess fibrosis and scarring after surgery and lack of proper postoperative care in the early and late periods following the surgery. This means that fistulas can keep on coming back even after surgery.

According to Dr. Samrat Jankar, a successful fistula surgery requires proper diagnosis, a perfectly performed and reported MRI, along with the surgeon’s expertise and the method of surgery. Dr. Samrat Jankar, the best fistula surgeon in Pune pioneer of the PILTEC procedure. In almost all cases Dr. Samrat Jankar performs a single-setting surgery with a success rate of more than 98% including fistula with perianal abscess. It is not only about surgery at kaizen gastro care dr Samrat Jankar and their team provide very good postoperative care which is one of the most important components in the complete cure of fistula.

What symptoms does anal fistula surgery address?
The signs and symptoms of an anal fistula include:

Frequent anal abscesses
Pain and swelling around the anus
Bloody or foul-smelling drainage (pus) from an opening around the anus. The pain may decrease after the fistula drains.
Irritation of the skin around the anus from drainage
Pain with bowel movements
Bleeding
Fever, chills, and a general feeling of fatigue
Anal fistula surgery aims to correct an anal fistula and treat all of its associated symptoms. If you have any of the above symptoms or you’re concerned about having an anal infection, abscess or fistula, speak with Kaizen fistula specialist Dr. Samrat Jankar, the best fistula doctor in Pune.

How is an anal fistula diagnosed at Kaizen Gastro Care:
Dr. Samrat Jankar at KAIZEN Gastro Care usually diagnoses an anal fistula by examining the area around the anus. He will look for an opening (the fistula tract) on the skin, then try to determine how deep the tract is, and the direction in which it is going. In many cases, there will be drainage from the external opening. Some fistulas may not be visible on the skin’s surface. Most of the time need further tests to better understand fistula relations with sphincter. An anoscopy is a procedure in which a special instrument is used to see inside your anus and rectum. Also in most cases, he advises an MRI fistulogram of the anal area to get a better view of the fistula tract. Some atypical cases need a colonoscopy to rule out IBD which will be the cause of the recurrence of fistula.

What causes an anal fistula?
The leading causes of an anal fistula are clogged anal glands and anal abscesses. Other, much less common, conditions that can cause an anal fistula to include:

Crohn’s disease (an inflammatory disease of the intestine)
Radiation (treatment for cancer)
Trauma
Sexually transmitted diseases
Tuberculosis
Diverticulitis
Colorectal Cancer
Post-operative care after fistula surgery
Take sitz baths (sit for 15-20 minutes in warm water with antiseptic solution) three times a day and after each bowel movement for the first few days.
If you were given a topical ointment, place this over the anal skin and a little into the anal canal 2-3 times a day.
Don’t worry if you have some bleeding, discharge, or itching during your recovery. This is normal.
Avoid constipation.
Take stool softener before bedtime every day till wound healing.
The use of dry toilet tissue should be avoided. After bowel movements use a jet water cleaning, if possible, followed by taking a warm bath.
If you were given a prescription for an ointment, apply these two or three times a day at the edge of the anal opening and inside by finger (not by applicator).
Eat a regular diet including plenty of fresh fruit and vegetables. Drink 6-8 glasses of water a day.
Connect with your surgeon if your temperature is greater than 101 degrees, significant bleeding, and unbearable pain.

Why Choose Kaizen Gastro Care for Fistula Treatment:
Experienced Fistula Specialist Team: Dr. Samrat Jankar is renowned as the best Fistula Specialist in Pune which is available at Kaizen Gastro Care Pune for treating various Piles, Fistula, and other anal diseases.
Advanced diagnosis and treatment: Kaizen Gastro Care provides a full range of diagnostic tests and innovative treatments which are used for the diagnosis and management of different Piles and Ananl conditions.
Clinic Location: Kaizen Gastro Care Clinic is located at the Pune and PCMC Prime location i.e. Wakad Area. This is the central location of Pune city. The patient can easily come with all public transport.
Leading-edge technology: Kaizen Gastro Care is equipped with leading-edge technology such as Endoscopy tests, Manometry, 24 Hr Ph Monitoring, Biopsy, and biofeedback. Also equipped with Piles Specialists and nutritionists.
A Dedicated Center for Fistula Treatment: Kaizen Gastro Care is the First Dedicated center for Fistula and different Anal Disease treatments in Pune and all over Maharashtra.
We Manage Your Care for the Long Term: We at Kaizen Gastro Care manage Piles, Fistula, and Anal disease for the long term. Kaizen Gastro Care manages the patients for the long term, taking regular follow-ups and long-term care.

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Contact Us
Kalosa Aesthetics & Cosmetic Gynaecology Clinic
Tara, B - 33, 34, Crescent Rd, Qutab Institutional Area, New Delhi - 110016
Phone: +91-8619751479, +91-9818816485
Email: info@kalosaaesthetics.com
Website: https://www.kalosaaesthetics.com/breast-lift/

Disclaimer: All the text, videos, techniques, and images available on this post are for awareness purposes only. It must not be considered as a substitute for medical advice. Results may vary from person to person, depending on the medical needs.