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Jul23

THE HOLY ANIMAL COW'S NEUTRALISING ANTIBODIES AGAINST "HIV " TO PRODUCE AN VACCINE AND ARV MEDICINE.


Prof Dr,DRAM,HIV /AIDS,HEPATITIS ,SEX DISEASES & WEAKNESS expert,New Delhi,India, +917838059592


The Cow the holy animal to whom we call as Mother as it gives a hygenic healthy Milk is now very important as it can produce good antibodies easily against a dreadly disease HIV for which no vaccine is present and once HIV means we have to take lifelong Medicines otherwise it recurs and if not treated bring a lot of oppurtunistic infections as TB, Diarrhoea,Cancer, Depression, Pneumonia etc. 
              Cow antibodies yield important clues for developing a broadly effective AIDS vaccine.The elicitation of powerful, HIV-blocking antibodies in cows in a matter of weeks -- a process that usually takes years in humans -- has now been described by researchers. The unexpected animal model is providing clues for important questions at a moment when new energy has infused HIV vaccine research.So Cows are leaving the pasture and entering the field of HIV vaccine research. As outlined in a study published in Nature, lead author Devin Sok, Director, Antibody Discovery and Development at the International AIDS Vaccine Initiative (IAVI), reports the elicitation of powerful, HIV-blocking antibodies in cows in a matter of weeks -- a process that usually takes years in humans.
              All four cows immunized with BG505 SOSIP elicited bnAbs(Broad neutralising antibodies ) to HIV within 35-52 days. In comparison, it takes HIV-positive humans multiple years to develop comparable responses, and only 5-15% even develop them at all.Many animal models does not yield any satisfactory result except COW.

            Cows cannot be infected with HIV, of course. But these findings illuminate a new goal for HIV vaccine researchers: by increasing the number of human antibodies with long loops, we might have an easier chance of eliciting protective bnAbs by vaccination.There is no doubt that cows' ability to produce bNAbs against a complicated pathogen like HIV in a matter of weeks, highlights even broader significance, particularly for emerging pathogens.Such research will help in reseraching medicines and vaccine agianst not only HIV but virus like Dengue,Influenza ,chikunguniya etc which infect us badly in modern times.



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