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Dr. Hitesh Modi's Profile
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India Spine Hospital
B-303 Rudra Arcade, Helmet cross road,
Memnagar, Ahmedabad 380052
Ph 8000014464/ 079 2746 7017
Consultation: Mon-Friday 4-7pm.
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Short segment pedicle screw fixation for unstable T11-L2 fractures: with or without fusion? A three-year follow-up study.
Acta Orthop Belg. 2009 Dec;75(6):822-7.
Short segment pedicle screw fixation for unstable T11-L2 fractures: with or without fusion? A three-year follow-up study.
Hwang JH, Modi HN, Yang JH, Kim SJ, Lee SH.
Source

Division of Spine Surgery, Department of Orthopedics, Konkuk University Hospital, Seoul, South Korea.
Abstract

In unstable thoracolumbar fractures T11-L2, exaggerated kyphosis at the end of treatment may predispose to late back pain and poor functional outcome. Short-segment (SS) (3 vertebrae) pedicle instrumentation has become a popular method of treatment. However the question to add a fusion or not is still under debate. The authors retrospectively evaluated the radiological and functional results in 74 patients who had undergone an SS pedicle screw fixation. They were divided into two groups: group 1 (39 patients) was the non-fusion group; group 2 (35 patients) was the fusion group. In the non-fusion group the mean preoperative, immediate postoperative and final kyphosis angles at the fracture site were respectively 20.8 degrees +/- 6.4, 8.2 degrees +/- 4.8, and 15.2 degrees +/- 6.0. In the fusion group the corresponding angles were 26.6 degrees +/- 4.1, 7.9 degrees +/- 2.1, and 8.4 degrees +/- 2.4, which demonstrated a distinctly better final result (p < 0.0001). In the non-fusion group the preoperative, immediate postoperative and final follow-up visual analog scores (VAS) for back pain were respectively 7.3 +/- 0.8, 3.9 +/- 0.8, and 3.4 +/- 0.9. In the fusion group the corresponding scores were 7.5 +/- 1.0, 3.9 +/- 1.1, and 1.6 +/- 0.7; the final result pleaded again in favour of fusion (p < 0.0001). Moreover, there were significantly more implant-related complications (screw loosening and breakage) in the non-fusion group (p < 0.0001). The authors conclude that fusion is advisable to obtain a better final outcome with respect to kyphosis and pain, and to avoid implant-related complications. However, at least one other study has led to the opposite conclusion: the issue remains controversial.

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Risk of developing seizure after percutaneous endoscopic lumbar discectomy.
J Spinal Disord Tech. 2011 Apr;24(2):83-92.
Risk of developing seizure after percutaneous endoscopic lumbar discectomy.
Choi G, Kang HY, Modi HN, Prada N, Nicolau RJ, Joh JY, Pan WJ, Lee SH.
Source

Department of Neurosurgery, Wooridul Spine Hospital, 47-4 Chungdam-dong, Seoul, Korea.
Abstract
STUDY DESIGN:

A retrospective analysis in patients who underwent percutaneous endoscopic lumbar discectomy (PELD) and developed seizures during the procedure; and to identify the risk of developing seizure during PELD by measuring cervical epidural pressure.
OBJECTIVE:

To evaluate clinical significance, characteristics, and risk factors for developing seizure and neck pain in patients undergoing PELD.
SUMMARY AND BACKGROUND DATA:

Increased epidural pressure during PELD has been reported earlier. Risk of developing intraoperative seizure has not been investigated till date. We experienced some unexpected complication such as, seizures during PELD, and, therefore, we correlated it with the prodromal symptom and the strategies to avoid such complications during PELD.
METHODS:

Four of the total 16,725 patients who underwent PELD between 2000 and 2008 developed intraoperative seizures. A review of their medical records and radiologic files were correlated with the complication. Factors evaluated were the type of seizures, prodromal symptoms, comorbidities and clinical outcome. To postulate a pathophysiologic cause of seizure, we designed a study to monitor the intraoperative cervical epidural pressure in 33 patients undergoing PELD.
RESULTS:

A striking feature of the 4 patients in this series was that they all complained of neck pain before the seizure event. There was no identifiable pattern of seizure observed. The duration of the procedure in these patients was longer than uninvolved cases. None of the patients developed any type of sequel subsequent to seizure. The outcome of surgery has been similar with the patients that did not have any type of complications after PELD. In the subsequent study of cervical epidural pressure, no patients developed seizure. However, there was occurrence of neck pain in the group with increased cervical epidural pressure.
CONCLUSIONS:

Although rare (0.02%), seizure can occur in patients undergoing PELD, occurrence of neck pain is correlated with increase in cervical epidural pressure, which should be considered as prodromal sign and alert the surgeon. Duration of procedure and speed of infusion are associated risk factor.

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Posterior multilevel vertebral osteotomy for severe and rigid idiopathic and nonidiopathic kyphoscoliosis: a further experience with minimum two-year follow-up.
Spine (Phila Pa 1976). 2011 Jun 15;36(14):1146-53.
Posterior multilevel vertebral osteotomy for severe and rigid idiopathic and nonidiopathic kyphoscoliosis: a further experience with minimum two-year follow-up.
Modi HN, Suh SW, Hong JY, Yang JH.
Source

Department of Orthopedics, Scoliosis Research Institute, Korea University Guro Hospital, Seoul, South Korea.
Abstract
STUDY DESIGN:

Prospective randomized study.
OBJECTIVE:

To evaluate the clinica! and radiologic outcome of posterior multilevel vertebral osteotomy (PMVO) in patients with severe kyphoscoliosis.
SUMMARY OF BACKGROUND DATA:

Authors have developed and reported results of PMVO for correction of neuromuscular scoliosis. PMVO has advantages such as, posterior-only procedure which avoids risk to pulmonary complications and gives satisfactory correction. However, its effect in correcting severe scoliosis in presence of rigid kyphosis has not been reported.
METHODS:

Thirteen patients (7 idiopathic, 4 cerebral palsy, and 2 congenital scoliosis) with severe and rigid kyphoscoliosis were operated by posterior-only correction with pedicle screw fixation using PMVO. As per pathology, and associated severity of kyphosis little modification in the original technique was applied while correction and osteotomy. Neuromonitoring was applied in all patients during operation. The radiologic and clinical results were evaluated with an average follow-up of 42.9±11 months. All postoperative complications were also noted during the follow-up period.
RESULTS:

Average number of osteotomy was 4.2±0.8 (range, 3-5). Average preoperative Cobb angle, pelvic obliquity, thoracic kyphosis, and lumbar lordosis were 99.2°±29.6°, 8.6°±9°, 73.6°±56.9°, and -47.2°±63.2°, respectively, which improved after surgery to 44.7°±12.3°, 2.8°±2.9°, 45.3°±15.9°, and -47.7°±12.2°. All corrections were maintained at final follow-up. A 54.3% correction was achieved in coronal plane; and, full correction was achieved in sagital plane as thoracic kyphosis was restored within normal range. Average blood loss and operative time was 3015±1213 mL and 6.01±1.09 hours, respectively. Three patients had postoperative respiratory complications; 2 had hemothorax and 1 had atelectasis; none had follow-up consequences. All pulmonary complications were due to associated thoracoplasty during which pleura was ruptured intraoperatively. Two patients had complication related with the implants; 1 screw breakage and other screw prominence. There was no neurologic injury intraoperatively on motor-evoked po- tentials (MEP) or clinically after surgery.
CONCLUSION:

PMVO exhibited satisfactory clinical and radiologic results in patients with severe and rigid scoliosis associated with hyperkyphosis at minimum 2-year follow-up. It can be safely applied with modifications in original technique for complex congenital scoliosis with multilevel hemi or block vertebrae and idiopathic/nonidiopathic spinal deformities.

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Surgical correction of paralytic neuromuscular scoliosis with poor pulmonary functions.
J Spinal Disord Tech. 2011 Jul;24(5):325-33.
Surgical correction of paralytic neuromuscular scoliosis with poor pulmonary functions.
Modi HN, Suh SW, Hong JY, Park YH, Yang JH.
Source

Department of Orthopedics, Scoliosis Research Institute, Korea University Guro Hospital, Seoul, South Korea.
Abstract
STUDY DESIGN:

A retrospective study.
OBJECTIVES:

To evaluate clinical and functional success by all pedicle screw construct in paralytic neuromuscular scoliosis (NMS) with poor pulmonary functions (PFT).
SUMMARY OF BACKGROUND:

Duchene muscular dystrophy and spinal muscular atrophy are often associated with poor PFT and the development of scoliosis simultaneously. Poor PFT often make surgeons reluctant to operate.
METHODS:

Eighteen paralytic NMS patients who had preoperative forced vital capacity (FVC) < 30% were operated with all pedicle screw construct. Average preoperative, postoperative, and final follow-up Cobb angle, pelvic obliquity, thoracic kyphosis and lumbar lordosis, PFT (FVC% and forced expiratory volume 1%), and preoperative and follow-up functional status were analyzed. Perioperative and postoperative complications were also noted.
RESULTS:

The average follow-up was 31.6 ± 7.7 months. There was significant improvement in Cobb angle (61.7%) and pelvic obliquity (56.7%), postoperatively (P < 0.001). All corrections were maintained at final follow-up. FVC was decreased from 25.2 ± 4.7% preoperatively to 24.2 ± 5.0%, 6 weeks postoperatively (P = 0.067); and on follow-up it further decreased to 20.6 ± 3.9% (P < 0.0001) (1.8%/y). Forced Expiratory Volume 1 also decreased from 22.7 ± 4.5% preoperatively to 21.8 ± 4.2% postoperatively (P = 0.037) and was 19.8 ± 3.8% at final follow-up (P < 0.0001) (1.1%/y). However, none of the patients had any respiratory complications postoperatively. Functional status was improved in 6 patients and they were able to sit without support (P = 0.027). Eight (44.4%) perioperative complications (5 pulmonary, 1 intraoperative death, and 2 others) were noticed. Postoperatively, 4 patients (23.5%) had complications; coccygodynia, back sore because of screw prominence, impingement of iliac screw, and loosening of the rod from L5 screw. All the patients were satisfied with the treatment. There were no major pulmonary complications requiring admission postoperatively.
CONCLUSIONS:

Although complications are associated with the treatment of paralytic NMS, a good clinical and function outcome suggests that poor PFT should not be considered as a contraindication of scoliosis surgery.

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Idiopathic scoliosis in Korean schoolchildren: a prospective screening study of over 1 million children.
Eur Spine J. 2011 Jul;20(7):1087-94. Epub 2011 Jan 28.
Idiopathic scoliosis in Korean schoolchildren: a prospective screening study of over 1 million children.
Suh SW, Modi HN, Yang JH, Hong JY.
Source

Scoliosis Research Institute, Department of Orthopedics, Korea University Guro Hospital, 80 Guro-Dong, Guro-Gu, Seoul, South Korea.
Abstract

Cross-sectional epidemiologic scoliosis screening was carried out to determine the current prevalence of scoliosis in the Korean population and to compare with the results of previous studies. Between 2000 and 2008, 1,134,890 schoolchildren underwent scoliosis screening. The children were divided into two age groups, 10-12-year-olds (elementary school) and 13-14-year-olds (middle school), to calculate age- and sex-specific prevalence rates. Children with a scoliometer reading ≥5° were referred for radiograms. Two surgeons independently measured curve types, magnitudes, and Risser scores (inter-observer r = 0.964, intra-observer r = 0.978). Yearly and overall prevalence rates of scoliosis were calculated. There were 584,554 boys and 550,336 girls in the sample, with a male to female ratio of 1.1:1. There were 77,910 (6.2%) children (26,824 boys and 51,086 girls) with scoliometer readings >5°, and 37,339 of them had positive results with Cobb angles ≥10° (positive predictive value, 46.4%). The overall scoliosis prevalence rate was 3.26%; girls had a higher prevalence (4.65%) than boys (1.97%). Prevalence rates increased progressively from 1.66 to 6.17% between 2000 and 2008, with the exception of 2002. According to age and gender, 10-12-year-old girls had the highest scoliosis prevalence rates (5.57%), followed by 13-14-year-old girls (3.90%), 10-12-year-old boys (2.37%), and 13-14-year-old boys (1.42%). In girls and boys, prevalence rates dropped by 64.53 and 60.65% among 10-12-year-olds and 13-14-year-olds, respectively (P = 0.00). The proportion of 10°-19° curves was 95.25 and 84.45% in boys and girls, respectively; and the proportion of 20°-29° curves was 3.91 and 11.28%, which was a significant difference (P = 0.00). Thoracic curves were the most common (47.59%) followed by thoracolumbar/lumbar (40.10%), double (9.09%), and double thoracic (3.22%) curves. A comparison of the curve patterns revealed significant differences between genders (P = 0.00). We present this report as a guide for studying the prevalence of idiopathic scoliosis in a large population, and the increasing trend in the prevalence of idiopathic scoliosis emphasizes the need for awareness.

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