Asthma is the most common chronic childhood disease in nearly all industrialised countries. An attack is experienced when the asthmatic child's chronically inflamed bronchial airways, having become sensitised to certain environmental allergens (e.g., dust, smoke) and conditions (e.g., exercise, cold weather, stressful emotions), begin to overproduce mucus in their presence.

This leads to the swelling and muscle contraction that obstructs air flow and restricts breathing. Although asthma has been known for millennia, but even after century a root cure of asthma is not yet available. The modern medicines of asthma can control the acute asthma symptoms, but did not cure this disease significantly.

In a recent research study conducted in Banaras Hindu University Varanasi; The children with age group of 2-12 years having symptoms of cough, fever, breathlessness, running nose, restlessness, wheezing, etc., were selected and divided into subgroup 'A' having positive history of taking bronchodilator and corticosteroid and subgroup 'B' having positive history of taking bronchodilator only whereas subgroup 'C' patients having no history of taking steroid or bronchodilator prior to the registration.

Patients were advised to take SKCR drug in a dose of 4 mg/kg/dose × 12 hrly (in powdered form) mixed in Garlic: Ginger: Honey (GGH) [in 1:2:4 ratio] to the patient and given for the 45 days.

The drug SKCR was given for a total of 45 days in a dose of 12 hourly with garlic, ginger and honey in ratio of 1:2:4. In most of the cases findings were suggestive of significant clinical improvement during the follow-ups.

In present study, analysis of incidence of common features in group 'A' all the signs and symptoms were subsided except the cough and wheeze in one case (10%) on third follow-up while on second follow-up approximately 40% cases relapsed after getting fresh exposure to the trigger factors during the management. In group 'B' and group 'C', incidence of most common features were subsided and all the patients had became asymptomatic on third follow-up.

This study suggested that the drug
SHWAS KASA CHINTAMANI RASA IS MORE EFFECTIVE IN THOSE CASES WHO ARE NOT RECEIVING CORTICOSTEROID WITH BRONCHODILATOR IN COMPARISON TO CHILDREN RECEIVING CORTICOSTEROIDS WITH/WITHOUT BRONCHODILATOR.

IT IS ALSO EFFECTIVE IN CHILDHOOD BRONCHIAL ASTHMA THAT HAS THE HISTORY OF STEROID AND BRONCHODILATORS. NO SPECIFIC ADVERSE EFFECT OF DRUG SKCR WAS OBSERVED.

(This research was conducted by researchers of Department of Kaumarbhritya, Faculty of Ayurveda, Banaras Hindu University, Varanasi,)

(ये सूचना आयुर्वेद विज्ञान के बारे में आपके ज्ञान वर्धन व इसके वैज्ञानिक दृष्टिकोण को समझाने हेतु है. किसी भी रोग से पीड़ित होने पर चिकित्सक के परामर्श से ही कोई दवा लें.)

HIV vaccine development necessary for a durable end to AIDS / HIV

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Broader global access to lifesaving antiretroviral therapies and wider implementation of proven HIV prevention strategies could potentially control and perhaps end the HIV/AIDS pandemic. However, a safe and at least moderately effective HIV vaccine is needed to reach this goal more expeditiously and in a more sustainable way, according to a new commentary from Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleague Hilary D. Marston, M.D., M.P.H.

In the piece, the authors note that behavioral, cultural and legal factors have hindered HIV prevention and treatment efforts and explain why those factors necessitate the development of an HIV vaccine. Although attempts to develop a vaccine have so far proven disappointing, recent advances offer encouraging areas for HIV vaccine researchers to pursue, according to the authors. Notably, the discovery of naturally occurring broadly neutralizing antibodies against HIV and studies of their stimulation in infected individuals have opened new avenues in vaccine development. Using improved understanding of those antibodies and the specific sites on HIV to which they bind, the natural process of antibody evolution could be replicated and greatly expedited allowing protection against initial infection. Significant advances also have been made in understanding T-cell responses that may be important to vaccine-induced immunity against HIV.

The authors conclude that "the HIV prevention community should hold fast to its commitment to vaccine science. Ultimately, we believe, the only guarantee of a sustained end of the AIDS pandemic lies in a combination of nonvaccine prevention methods and the development and deployment of a safe and sufficiently effective HIV vaccine."

AIDS:UN DECLARATION ZERO HIV / ZERO DISCRIMINATION BY 2015

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There are 22 priority countries; they have the highest number of pregnant women living with HIV, as recognised in the ‘Global Plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive’.Global plan was formulated by 110 countries of World in UN HQ by formulating 10 TARGETS ,THE GOAL TO BE COMPLETED BY 2015 WITH YEARLY SURVEILLANCE AND MONITORING OF PROGRAMME AND ITS SUCCESS AND HINDRANCE to combat hiv/aids spread,contamination and new cases to promote zero tolernce for hiv/aids,no new cases or ZERO HIV NEW INFECTION AND DEATH DUE TO AIDS by good funding of screening every person for HIV/AIDS and providing primary and secondary treatment for every infected person in countries like india,and other sian countries and countries of AFRICA AND LATIN AMERICA and to extend insurance sector to HIV /AIDS IN USA BY PRESIDENT PROFAR PROGRAMME,ZERO DISCRIMINATION OR STIGMA for HIV LIKE A BILL IN UPPER HOUSE IN INDIA to punish those who discriminate HIV /AIDS.
These 22 countries are: Angola, Botswana, Burundi, Cameroon, Chad, Côte d’Ivoire, Democratic Republic of the Congo, Ethiopia, Ghana, India, Kenya, Lesotho, Malawi, Mozambique, Namibia, Nigeria, South Africa, Swaziland, Uganda, United Republic of Tanzania, Zambia, and Zimbabwe. India is the only country not in Africa.
10 TARGETS SETS UNIVERSALLY TO COMBAT HIV/AIDS WITH SPECIAL FOCUS ON ABOVE 22 COUNTRIES ARE AS FOLLOWS:-----.

1.Reduce sexual transmission of HIV by 50% by 2015
2.Halve the transmission of HIV among people who inject drugs by 2015
3.Eliminate HIV infections among children and reduce maternal deaths
4.Reach 15 million people living with HIV with lifesaving antiretroviral treatment by 2015
5.Halve tuberculosis deaths among people living with HIV by 2015
6.Close the global AIDS resource gap
7.Eliminate gender inequalities and gender-based abuse and violence and increase the capacity of women and girls to protect themselves from HIV
8.Eliminate HIV-related stigma, discrimination, punitive laws and practices
9..Eliminate HIV-related restrictions on entry, stay and residence
10.Strengthen HIV integration — with Sikkim Aids Empl Assocn and 15 others. (4 photos)

HIV /AIDS: ARV MEDICINES : SOME TRUTHS & MYTHS OF TREATMENT FOR HIV /AIDS PATIENTS FOR BETTER ADHERANCE & CURE

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Antiretroviral therapy -- or ART -- A COMBINATION OF 3-4 DRUGS COMPRISING OF EITHER NRIT OR NNRITS WITH PROTESE INHIBITOR WITH FUSION OR INTEGRASE INHIBITOR OR RECEPTOR BLOCKE revolutionized HIV treatment in the past few decades. And newer improvements, like one-pill-a-day drugs,or injections once a quarter as i wrote in my last article,are making life with HIV easier and safer.
Like chronic disease as hypertension,Diabetes,thyroid or Kidney or cancer we have to take this medicines regularly without any fail and if we do so we shall get Viral load or quantity of virus in our body decreses and our defense cell cd4 population rises and we live a normal life and no opputunistic infections like tb,diarrhoea,skin rashes,ulcers or mouth lesion or fungal infection attacks us.decision to which drug to be used is a complcated one and only an experienced doctor keeping details of type of patients,exposures and presence of infections and general condition of patients and personal history of pt and economical conditions all gives input to DOCTOR TO SELECT DRUG ON EXPERIENCE and DOCTORCHANGES IT IF RESPONSE IS NOT COMING OR ADD SOME MORE IF OPPUTUNISTIC OR OTHER SYMPTOS DEVELOP.
SO SELF MEDICATION OR MEDICATION ONSIMPLE NET OR TELEPHONIC ADVICE ARE DANGEROUS AND SHOULD BE NEVER TAKEN.TILL NOW ALTERNATIVE HERBAL MEDICINES EFFICACY IS NOT PROOVED SO NEVER TRUST THEM AND AVOID THEM EXCEPT SOME VITMINS,FOOD SUPPLEMENTS AND EXCERCISES.

5 Things to Know About HIV Medications;--
There are lots of myths and stale, outdated information about HIV treatment. Here are five things you should know about ART.
It's easier to take than it used to be. A lot of people with HIV just take one pill once a day. That's it. That one combination pill -- Atripla, Complera, or Stribild -- packs in all the different active ingredients you need. Most people don't need the "cocktails" with complicated dosing schedules anymore.
You have lots of options. Some people need drug combinations. There are six classes of antiretroviral drugs for HIV and more than 30 drugs. If one doesn't work or causes side effects, the doctor has many other choices.
Medications work for a long time. People used to worry that their drugs would stop working after a while and that they'd have to keep switching to new ones. That's not really a risk now. "As long as you keep taking your medications, the same treatment can work for decades," Hare says.
Drugs have fewer side effects. While specific side effects depend on the drug, HIV treatment is much safer and easier to tolerate than it used to be. For most people, side effects -- like upset stomach and diarrhea -- are minor and often go away. Long-term risks include cholesterol problems and weakened bones. But even so, the risks of treatment are much lower than the risks of not getting it, Hare says.
You may start taking medication as soon as you're diagnosed. Many experts believe that the sooner you start treatment, the better. However, some doctors prefer to wait until your CD4 count, a measure of some immune cells, drops to a certain point before starting treatment. See what your doctor recommends.

HIV /AIDS :CAUSTIONS BEFORE AND AFTER TREATMENT

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HIV /AIDS only methos to control it is by medicines ARV ,mostly a combination of recently investigated and discovered 3-4 medicines WHICH CURES VIRUS BUT PRODUCE MANY SIDE EFFECTS,SO SHOULD BE TAKEN AFTER PRECRIBED BY A GOOD EXPERT DOCTOR,self or over the table or counter medicines may produce many lethal side effects and complications.
doctors write thesr medicines specifically needed for one person or individually as his way of exposure,duration of symptos,presence of any oopurtunistic infections,his blood tests like CD$,Viral Load,CBC,LFT,KFT, LIPIDPROFILE, HBSag,HCV,VDRL,urine R/E,urine C/S,Stool for R/E ,CXR,ECG,USG of Abdomen etc are main tests needed to be done before starting therapy as presence of ny TB,STDs,Pneumonia,Diarrhoea or skin rash may produce unlike effects and complications and so medicines will change from one person to other considering his /her food habit,any addiction history,physical built,personal history of excercise and mental status and attitude.
Short-Term Side Effects of HIV Treatment:
HIV treatment can cause side effects for a brief period while it is controlling the virus in your body. Common short-term side effects include:
Fatigue
Anemia, a problem with red blood cells that may also cause fatigue
Diarrhea, nausea, or vomiting
Dizziness or headaches
Insomnia
Pain and nerve problems
A skin rash
Injection site reactions
Dry mouth
Weight loss
Vivid dreams
Although these side effects may bother you for a while, they frequently get better with time -- often within a few weeks.If side effects do not lessen, or if they are severe or unusual, then Doctor will decide whether to continue medicines or not as Heapatitis leading to high jaundice or severy skin rashes as Stevns Jhonson syndrome or severe depression or loss of sleep or night mares,so severe anaemia or lipidostrophy may bound him to stop some medicines and start new mediicines..

Doctor examines that CD$ rises and Viral load decreases if not then he suspects Viral Resistant with medicines so if affordable drug sensitivity test or otherwise randomly he stars new medicine out of one group.During this one has to take medicines regularly without any fail,good diet,excecise,and no addiction of alcohol,nicotine,drugs and good sexual habit with safe sex and no contamination with infected blood or semen.
Coping With Long-Term Side Effects of HIV Treatment:
Some of the most common long-term side effects and coping strategies include:
Fat redistribution. Known as lipodystrophy, this can occur when the body changes the way it produces, uses, and stores fat. You might lose fat in your face and legs and gain fat in your abdomen and back of your neck. Switching medications may keep symptoms from getting worse. But there are few other options for treating this long-term side effect.
Increases in cholesterol or triglycerides. This can increase the risk for problems such as heart disease. Diet and other lifestyle changes are a first step. Medications such as statins and fibrates may also be recommended by your doctor.
Elevated blood sugar levels. Exercise, weight management, and other lifestyle changes may help. Your doctor may also recommend other medications to control blood sugar levels.
Decreases in bone density. This can increase the risk of bone fractures, especially as you get older. Try weight-bearing exercises like walking or weight lifting. Your doctor may recommend calcium and vitamin D supplements, or medications to treat or prevent osteoporosis.
A buildup of a cellular waste product. Known as lactic acidosis, this uncommon issue can cause a wide range of problems, from muscle aches to liver failure. You may need to switch drugs.kidney stones can also occur so one has to take more water intake,side by side if any oppurtunistic infection then Cotraimaxazole for Pneumonia,Dirrhoea,toxoplasma ,cytomegal onfection,anti fungal for fungal infection and treatment for TB etc has to be taken.During start of such treatment "IRIS" or a special reaction may develop but subsides with steroid and regular treatment .