Syphillis
Posted by on Wednesday, 28th September 2016
Syphilis is a sexually transmitted disease caused by the bacteria Treponema pallidum.
Primary syphilis
Secondary syphilis
Syphilis cannot be contracted through toilet seats, daily activities, hot tubs, or sharing eating utensils or clothing.
Syphilis is a bacterial infection usually spread by sexual contact. The disease starts as a painless sore on your genitals, mouth or another part of your body. If untreated, syphilis can damage your heart and brain.
Syphilis progresses in stages and can lead to serious complications or death. Having syphilis also makes you more vulnerable to HIV. When caught early, syphilis can be cured with antibiotics.
Symptoms
Syphilis develops in four stages, and symptoms vary with each stage. But the stages may overlap, and symptoms don't always occur in the same order. You may be infected with syphilis and not notice any symptoms for years.
Primary syphilis
These signs may occur from 10 days to three months after exposure:
A small, firm, painless sore (chancre).
The sore will heal without treatment, but the syphilis infection remains. In some people, syphilis then moves to the secondary stage.
Secondary syphilis
The signs and symptoms of secondary syphilis begin two to 10 weeks after the chancre appears and may include:
Skin rash, often appearing as rough, red or reddish-brown, penny-sized sores, over any area of your body, including your palms and soles
Fever
Fatigue and a vague feeling of discomfort
Soreness and aching
Swollen lymph glands
Sore throat
Wart-like sores in the mouth or genital area
These signs and symptoms may disappear within a few weeks or repeatedly come and go for as long as a year.
Latent syphilis
If you aren't treated for syphilis, the disease moves from the secondary to the latent (hidden) stage, when you have no symptoms. The latent stage can last for years. Signs and symptoms may never return, or the disease may progress to the tertiary (third) stage.
Tertiary or late syphilis
About 15 to 30 percent of people infected with syphilis who don't get treatment will develop complications known as tertiary, or late, syphilis. In the late stages, the disease may damage your brain, nerves, eyes, heart, blood vessels, liver, bones and joints. These problems may occur many years after the original infection.
Some of the signs and symptoms of late syphilis include:
Jerky or uncoordinated muscle movements
Paralysis
Numbness
Gradual blindness
Dementia
Congenital syphilis
If you're pregnant, you may pass syphilis to your unborn baby. Blood containing the bacteria reaches the fetus through the placenta, the organ that nourishes the developing baby. This is known as congenital syphilis.
Most infants born with syphilis have no symptoms of the disease. Almost all develop symptoms by 3 months of age, though some children with congenital syphilis show no signs of the disease until after age 2.
Early signs and symptoms, which occur before the age of two, may include:
"Snuffles" (runny nose)
Skin sores
Rashes
Fever
Jaundice — yellow skin
Infection of the umbilical cord
Anemia
Swollen liver and spleen
If not treated right away, the baby may experience serious problems, including:
Deformities
Tooth abnormalities
Deafness
Developmental delays
Seizures
Death
What is the treatment for syphilis?
Syphilis is treated with various Antibiotics. The amount of reatment depends on the stage of syphilis the patient is in. Pregnant women with a history of allergic reaction to penicillin should undergo penicillin desensitization followed by appropriate penicillin therapy. A baby born with the disease needs daily penicillin treatment for 10 days.
What can be done to prevent the spread of syphilis?
There are number of ways to prevent the spread of syphilis:
• Limit your number of sex partners;
• Use a male or female condom;
• If you think you are infected, avoid sexual contact and visit your local STD clinic, a hospital or your doctor;
• Notify all sexual contacts immediately so they can obtain examination and treatment;
• All pregnant women should receive at least one prenatal blood test for syphilis.
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Chancroid
Posted by on Wednesday, 28th September 2016
Chancroid also known as soft chancre is a bacterial disease caused by bacteria called Haemophilus ducreyi that is spread only through sexual contact.
Causes
Chancroid is caused by a type of bacteria called Haemophilus ducreyi.
Symptoms
Within 1 to 10 days after getting chancroid, a person will get a small bump in the genitals. Within a few days, these bumps become filled with pus and eventually rupture, leaving painful, open sores in the genital region. These open sores are known as ulcers, and can range from one to three centimeters in diameter.
The ulcer:
• Ranges in size from 1/8 inch to 2 inches across
• Is painful
• Is soft
• Has sharply defined borders
• Has irregular or ragged borders
• Has a base that is covered with a grey or yellowish-grey material
• Has a base that bleeds easily if banged or scraped
About half of infected men have only a single ulcer. Women often have 4 or more ulcers. The ulcers appear in specific locations.
Common locations in men are:
• Foreskin (prepuce)
• Groove behind the head of the penis (coronal sulcus)
• Shaft of the penis
• Head of the penis (glans)
• Opening of the penis (urethral meatus)
• Scrotum
In women the most common location for ulcers is the outer lips of the vagina (labia majora). "Kissing ulcers" may develop. These are ulcers that occur on opposite surfaces of the labia.
Other areas such as the inner vagina lips (labia minora), the area between the genitals and the anus (perineal area), and inner thighs may also be involved. The most common symptoms in women are pain with urination and intercourse.
The ulcer may look like a chancre, the typical sore of primary syphilis.
Approximately half of the people infected with a chancroid will develop enlarged inguinal lymph nodes, the nodes located in the fold between the leg and the lower abdomen.
Half of those who have swelling of the inguinal lymph nodes will progress to a point where the nodes break through the skin, producing draining abscesses.
The swollen lymph nodes and abscesses are often referred to as buboes.
Tests
Chancroid is diagnosed by looking at the ulcer(s) and checking for swollen lymph nodes. There are no blood tests for chancroid.
Treatment
The infection is treated with antibiotics. Large lymph node swellings need to be drained, either with a needle or local surgery.
Chancroids in persons with HIV may take much longer to heal.
Prevention
Chancroid is a bacterial infection that is spread by sexual contact with an infected person. Avoiding all forms of sexual activity is the only absolute way to prevent a sexually transmitted disease.
However, safe sex behaviors may reduce your risk. The proper use of condoms, either the male or female type, greatly decreases the risk of catching a sexually transmitted disease.
You need to wear the condom from the beginning to the end of each sexual activity.
If you are currently sexually active, or are thinking about becoming sexually active, it is important to become familiar with all of the health risks involved. Unprotected or unsafe sexual practices can dramatically increase your risks of developing a sexually transmitted disease (STD).
Many of these STDs have a number of unpleasant side effects and can lead to severe health complications.
Comparison with Chancre (Syphilitic)
There are many differences and similarities between the conditions syphilitic chancre and chancroid (reference 1 and 2)
Similarities
• Both originate as pustules at the site of inoculation, and progress to ulcerated lesions
• Both lesions are typically 1-2 cm in diameter
• Both lesions are caused by sexually transmissible organisms
• Both lesions typically appear on the genitals of infected individuals
• Both lesions can present at multiple sites and with multiple lesions
Differences
• Chancre is a lesion typical of infection with the bacterium that causes syphilis, Treponema pallidum
• Chancroid is a lesion typical of infection with the bacterium Haemophilus ducreyi
• Chancres are typically painless, whereas chancroid are typically painful
• Chancres are typically non-exudative, whereas chancroid typically have a grey or yellow purulent exudate
• Chancres have a hard (indurated) edge, whereas chancroid have a soft edge.
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Chlamydia Infection
Posted by on Wednesday, 28th September 2016
Chlamydia infection is a common sexually transmitted infection (STI) in humans caused by the bacterium Chlamydia trachomatis. Chlamydia is a major infectious cause of human genital disease. Chlamydia infection is one of the most common sexually transmitted infections worldwide.
Chlamydia can be transmitted during vaginal, anal, or oral sex, and can be passed from an infected mother to her baby during vaginal childbirth.
In men, infection of the urethra (urethritis) is usually symptomatic, causing a white discharge from the penis with or without pain on urinating (dysuria).
Occasionally, the conditions spreads to the upper genital tract in women (causing pelvic inflammatory disease) or to the epididymis in men (causing epididymitis). If untreated, chlamydial infections can cause serious reproductive and other health problems with both short-term and long-term consequences.
Signs and symptoms
Genital disease
Chlamydial cervicitis in a female patient characterized by mucopurulent cervical discharge, erythema, and inflammation.
Male patients may develop a white, cloudy or watery discharge (shown) from the tip of the penis.
Chlamydial infection of the neck of the womb (cervicitis) is a sexually transmitted infection which is asymptomatic for about 50-70% of women infected with the disease.
The infection can be passed through vaginal, anal, or oral sex. Of those who have an asymptomatic infection that is not detected by their doctor, approximately half will develop pelvic inflammatory disease (PID), a generic term for infection of the uterus, fallopian tubes, and/or ovaries. PID can cause scarring inside the reproductive organs, which can later cause serious complications, including chronic pelvic pain, difficulty becoming pregnant, ectopic (tubal) pregnancy, and other dangerous complications of pregnancy.
Symptoms that may occur include: unusual vaginal bleeding or discharge, pain in the abdomen, painful sexual intercourse (dyspareunia), fever, painful urination or the urge to urinate more frequently than usual (urinary urgency). Low back pain, nausea, fever, pain during intercourse, or bleeding between menstrual periods. Chlamydial infection of the cervix can spread to the rectum.
Men with signs or symptoms might have a discharge from their penis or a burning sensation when urinating. Men might also have burning and itching around the opening of the penis. Pain and swelling in the testicles are uncommon.
In men, Chlamydia shows symptoms of infectious urethritis (inflammation of the urethra). Symptoms that may occur include: a painful or burning sensation when urinating, an unusual discharge from the penis, swollen or tender testicles, or fever. Discharge, or the purulent is generally less viscous and lighter in color than for gonorrhea. If left untreated, it is possible for Chlamydia in men to spread to the testicles causing epididymitis, which in rare cases can cause sterility if not treated within 6 to 8 weeks. Chlamydia is also a potential cause of prostatitis in men.
Perinatal infections
As many as half of all infants born to mothers with chlamydia will be born with the disease. Chlamydia can affect infants by causing spontaneous abortion; premature birth; conjunctivitis, which may lead to blindness; and pneumonia.
Treatment
C. trachomatis infection can be effectively cured with various antibiotics once it is detected.
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Genital Wart
Posted by on Wednesday, 28th September 2016
Classification and external resources
Severe case of genital warts around the anus
Genital warts (known as condylomata acuminata or venereal warts) may be small, flat, flesh-colored bumps or tiny, cauliflower-like bumps. In men, genital warts can grow on the penis, near the anus, or between the penis and the scrotum. In women, genital warts may grow on the vulva and perineal area, in the vagina and on the cervix (the opening to the uterus or womb). Genital warts vary in size.
Genital warts are caused by the human papillomavirus (HPV). There are many kinds of HPV. Not all of them cause genital warts. HPV is associated with cancer of the vulva, anus and penis. However, it's important to note that HPV infection doesn't always lead to cancer.
Cause
HPV is a sexually transmitted infection (STI). The most common way to get HPV is by having oral, vaginal or anal sex with someone who is infected with HPV. The only sure way to prevent genital warts is to have sex. Sex only with a partner who is not infected with HPV.
Just because you can't see warts on your partner doesn't mean he or she doesn't have HPV. The infection can have a long incubation period. This means that months can pass between the time a person is infected with the virus and the time a person notices genital warts. Sometimes, the warts can take years to develop. In women, the warts may be where you can't see them--inside the body, on the surface of the cervix.
Using condoms may prevent you from catching HPV from someone who has it. However, condoms can't always cover all of the affected skin.
Symptoms
In many cases genital warts do not cause any symptoms, but they are sometimes associated with itching, burning, or tenderness. They may result in localized irritation.
Women who have genital warts inside the vagina may experience bleeding following sexual intercourse or an abnormal vaginal discharge. Rarely, bleeding or urinary obstruction may occur if the wart involves the urethral opening.
Treatment
Depending on the sizes and locations of warts (as well as other factors), a doctor will offer one of several ways to treat them. Podofilox is the first-line treatment due to its low cost.
Podofilox solution in a gel or cream can be applied by the patient to the affected area and is not washed off. Podofilox is safer and more effective than podophyllin.
Podophyllin and podofilox should not be used during pregnancy, as they are absorbed by the skin and could cause birth defects in the fetus.
Cryotherapy: This technique freezes the wart using liquid nitrogen or a "cryoprobe." It is an excellent first-line treatment because response rates are high with few side effects.
Laser treatment: This treatment is used for extensive or recurrent genital warts. It may require local, regional, or general anesthesia. Disadvantages include high cost, increased healing time, scarring.
Electrodesiccation: This technique uses an electric current to destroy the warts. It can be done in the office with local anesthesia. Of note, the resulting smoke plume may be infectious.
Surgical excision is best for large warts, and has a greater risk of scarring.
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Molluscum Contagiosum
Posted by on Wednesday, 28th September 2016
Molluscum contagiosum (MC) is a viral infection of the skin. It is caused by poxvirus called the molluscum contagiosum virus (MCV). Molluscum contagiosum lesions are flesh-colored, dome-shaped, and pearly in appearance. They are often 1–5 millimeters in diameter, with a dimpled center.
The MC rash initially appears as smooth, pearly to flesh-colored, dome-shaped papules. With time, the center becomes soft and indented (umbilicated) with a white curdlike core.
Molluscum contagiosum (MC) that was first described in 1817. It is common worldwide and accounts for about 1% of all skin disorders in the United States.
Typically, the lesion of molluscum begins as a small, painless papule that may become raised up to a pearly, flesh-colored nodule. The papule often has a dimple in the center.
This common viral disease has a higher incidence in children, sexually active adults, the infection is most common in children aged one to ten years old. MC can affect any area of the skin but is most common on the trunk of the body, arms, and legs. It is spread through direct contact or shared items such as clothing or towels.
The virus commonly spreads through skin-to-skin contact. This includes sexual contact or touching or scratching the bumps and then touching the skin.
It primarily affects children (boys more often than girls).
Molluscum Contagiosum Causes
Molluscum contagiosum is transmitted by direct contact, either person to person or by shared items, such as clothing, towels, and washcloths.
Outbreaks have occurred in the following settings:
swimming pools,
wrestling matches,
during surgery, by a surgeon with a hand lesion (sore),
having tattoos (rare), and
Sexually: It is likely that genital lesions are sexually transmitted.
Lesions develop within two to three months after exposure. Some doctors consider MC a sexually transmitted disease in adolescents and adults and recommend that people with genital MC be tested for other STDs. However, not all genital lesions in adults are sexually transmitted.
Usually, there is no itching or tenderness, and there are no generalized symptoms such as fever, nausea, or weakness.
Medical Treatment
Removal of lesions reduces the rate of spread to other people as well as from one part of the body to another.
Genital lesions in adults should be treated in order to prevent spread through sexual contact.
The most popular treatments are scraping of the lesions (called curettage) or removal using heat (called cautery) or cold (called cryotherapy, a procedure performed with liquid nitrogen).
In children, the papules typically appear on the face, neck, armpits, hands and arms. In adults, molluscum contagiosum may be a sexually transmitted disease (STD) and is usually seen on the genitals, lower abdomen, inner upper thighs and buttocks.
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