NEW RESEARCH IN MICE SHOWS AGEING CAN BE REVERSED BY STEM CELLS;-----
Ageing is the process which cannot be reversed as the man or animal who has taken birth has to die one day,maximum age for human being is 100 yrs.Our skin ,nerves,hear lung,intestines,bones ,muscles every part starts showing feature of old age and we becomes older and older these tissue becomes mor older and show signs of decaying and loss in structure,function and minor intracellular biochemical activities and ultimately one has to die.
man has conqured the world by reseach of Dolly by producing a replica of a person 100% by on cells without needing fetilisation from oppisite partner egg by establishing and harvesting stem cells or embroyinc cells of primitive or primodial cells which is the mother cells of every thing.As blood and skin and endothelium of intestines are rapidly replaced every day so here Stem cells does a remarable work ,they remain exist here even in old age and Bone marrow which forms all type of blood cells is the store house of these blood stem cells which produce different type of Blood cells.Bone marrow produce myeloid and lymphoid type of blood cells,Myeloid is concerned for producing immune cells resulting in productions of fighting blood cells which helps us o prevent inflammation by infection and cancer.But some lymphoid cells help our body to repair or rejuvenate old cells or tissue.In young mice Myeloid cells are produced in less number than Lymphoid cells but in old Mice Lymphoid are in less number produced,so repair work in not done properly but after injecting stem cells (or blood )from young Mice is injected in to old Mice it travels to Bone Marrow of old Mice and stimulate it to produce lympoid cells so that repair of old tissue being undertaken very rapidly as old Tissue are repaired Ageing Process is being reversed.
This study has been done in Mice only but not in Human Being but as more research will further clear the picture,Man will be immortal as only limitation OF IMMORTALITY is the fact that all body tissue usually becomes old and self decay and destruction is the cause of death of tissue or human being as Man has conquered over diseases and infections but cannot control self dying process and by such invention the last hurdle of Man Being Immortal will be also removed.
By mixing blood of old people with the blood of young people ,these young bllod cells rejuvenate old blood cells .This has been demonstrated by THE HAVARD STEM CELL INSTITUTE by a recent published study on Mice.When blood from young mice bone marrow injected in old mice,these blood cells after entering into Bone Marow of Old mice revitalise these Blod Stem Cells present in Bone Marrow.Reseacher concluded that usually in old Mice Bone marrow produce that type of Blood stem cells which generate more Myeloid series blood cells which control infection or tumors but less amount of Blood stem cells whch produce Lymphoid series cells that orchestrate or regenerate tissue Repair as seen in young Mice but after the injectionof young blood cells even old Mice started producing stem cells that is doing tissue repair.The study is yet to be done in Human being.
hence such study is most important mile stone in life of Human being as now man can produce own replica by oneself,can kill any infection ,defeat any metabolic,cardivasular,immunological or herditory disese but now by this study old age will be turned into young age and Man will live for years as he wants to live or he will be IMMORTAL.
Dr.D.R.Nakipuria

-HOW TO PERFORM ? A MODERN PERSPECTIVE & DEFINITION
---DR.D.R.NAKIPURIA
SEX although cannot be discussed or expressed openly in our society as it is a topic of intense personal matter and allowed to discuss by grown up or adults or matured in personal couple group or an advice by seniors to upcoming matured adults to practise it as per their experience.Beside this our society think its discussion may destroy social fabric as may stimulate youngster in early sexuality or indulgence of adults and old in abnormal sexuality beside legal partner.SEX has been broadly defined as meeting of two partners of opposite sex or meeting two external genital organs of opposite sex whether any pleasure or satisfication is achieved by this or not.As man has got Penis and it is penetrated in to vagina through introitus by man so he is called active partner and as female simply receives Penis so is called Passive partner but modern detail analysis of patients achieving full satisfication and pleasure by Sex and persons remaining unsatisfied and psychosocially disturbed after Sex has redefined this definition of SEX.
it is very important for a man being active partner realise very much,any defect in performance of Sex either of arousal or desire or LIBIDO or lack of excitement on stimulation by seeing or reading sexual activities or seeing or touching opposite sex partner or her activity or by stimulation through eyes,talk,exhibition or touch of partner or self induced involuntary erection( under influence of body hormones) i.e.,tightening,straightening,thickening and hardening of penis with slight secretion of seminal fluid over glans region with easy slipping of foreskin over it or called as ERECTION or it may be failure of pushing this erect penis in partner’s vagina through introitus or Ext.Genitilia Vulva or discharge of Seminal fluid into vagina immediately after penetration i.e.,EARLY EJACULATION resulting in loss of satisfication and pleasure as strokes gives more and more pleasure which reaches to peak slowly keeping pace with speed and force applied for stroke.by penis.The force is more applied by a thickened, tightened and straight erected penis ,that is why a good erection is mandatory for a good performance of sex.lack of such erection is called Erectile Dysfunction(ED).This enjoyment becomes more excited as partner’ vagina contracts involuntary or by active contraction of Pelvic muscles by partner is increased.Therefore ,apathy of partner,less excitement or lack of attention in sex by partner or deficiency of active cooperation and actions in Sex also result in getting good satisfication and pleasure.Female although by misnomer called as inactive partner but actually her cooperation from the stage of getting desire,attention,environment of Sex to getting aroused or ORGASM either by self excitement or by stimulation by partner by look,touch or reading books or watching video etc.,or after fourplay by partner which is very important in Female as they are less easily excited or reach peak to Orgasm and without her active cooperation Sex remains less pleasant and unfulfilled in satisfication.Role of Accessory or additional Genital organs like Body contour,Pubic Hairs,Moustache,hairs over chest/limbs(in Male),Face color of Body,color of Iris of eye ,shape,size of Eyes,Placement of Eyebrows,straight beak like nose,mouth opening,lips ,fore head,style of hairs over scalp,and contour,fullness,bogginess tightening,size ,shape resistance,compressibility of breast with coloring of areola and stargtening of nipples with shape of belly being scaphoid and centrally placed elliptical umbilicus ,proturbance of buttocks,broadening of Hips with slender slim straight fingers,toes limbs, soft palm and sole with absent of hairs over any part of body except straight small shiny pubic hairs with thickened puffy Labial folds is very important as they play indirect role to either initiate Sex or Libido or later to maintain Sex or good performance or more sustainable play.Early Ejaculation leads to flaccid ,small ,shrunken Penis which freezes immediately a Male partner as female is either at peak of orgasm or getting arousal for orgasm ,such sudden discharge makes her completely dissatisfied and uncomfortable as shrunken flaccid penis cause no dilatation of strchable compressed thickened roomy vagina or touching of cervix of Uterus or deep pockets of vagina around cervix or fournix .So either expressed by modern educated Female partner voluntarily or involuntarily expressed by face or body activities immediately or on subsequent occasion of Sex initiation by male partner who realises this as his biggest failure and suffer from self realised Gilty consciousness leading to Psychosocial disbalance leading to further damage in getting arousal or erection or performance of sex and vice versa.
Therefore,we have realised that sex is no more confined to one partner ,one partner may be less active but other partner can make him co active similiarly an uninterested or freezed partner can freeze or dissatisfy another partner.Previously if one partner is not performing particularly a male doesnot get erection or arousal to perform sex we called it IMPOTENCE and similiary a female doesnot get pregnancy after intercourse we called IMPOTENCE but it should be better termed as INFERTILITY but now a days sex has been better defined as stated above in following stages.
StgageI: Self or stimulated Aroursal and arousal of partner with full Orgasm.
Stage II:Erection of penis with penetration and reception of such erected penis by an active partner.
Stage III;-Mantenance of coital activites by cooperation of both partner ( both are as active no active or passive nomenclature).
StageIV;-Discharge or Ejaculation of Seminal fluid in vagina or condom or ouside gradually allowing partner to cool gradually and slowly.
Sex in different positions or in different openings beside vagina as Anal or oral or Arm pit sex is not called perversion but resource to achieve more pleasure and satisfication in which any of these four stage is fortified depending on which separate methodology we adopt like kissing or messaging of Breast increase stage I and III ,oral ,armpit and anal sex improves stage II,III and IV.Sex with children or old people or desibilated or mentally retarded people or against will of partner forcefully or under intoxification with alcohol ,drugs or sleeping pills is a crime and this needs no discussion as it is always painful .SEX IS A RESOURCE TO BRING JOY, HAPPINESS , SATISFICATION,LIKENESS,ADHERANCHE AND MORE HUMAN BONDAGE WITH LOVE IN LIFE IF IT PAINS EITHER PARTNER DURING OR AFTER PERFORMANCE IT SHOULD NOT BE CALLED SEX.Sex ,how much discarded for discussion openly in society is need of human being to mantain its progeny in universe but Sex is the only simple natural method of producing future generation but every act of Sex is not necessarily mean production as Human has reached highest growth in Animal Kingdom,he has to restrict the number of his progeny,that is why he has learned to enjoy Sex without production by developing so many methods of contraception like Condom,spermicidal jelly tablets,foams ,vaginal condom,pessary jellies,IUCDs ,oral contraceptive pills/injections/patches for female and male,sex during safe period,external ejaculation etc.,
Lack of availability of partner in war time battalions leads to sex with same sex partner and gradually a class of people called as GAY or LESBIANS has evolved in society in good number across the globe,they are perfect Humanbeings with good mental and social judgement but they got enjoyment with same sex or HOMOSEXUAL.They are no more defined as perverted or sexually abnormal persons ,many countries provide their activity as normal as Sex among HETROSEXUAL exist.even in India,their such act is now not under any screeing of unlawful activity.gradual wecome and accept of these Homosexual have added further definition of SEX where in Stage II erection of penis or penetration of Penis may or may not present and partner may utilise aroused finger /hand /toe or any soft compressible toy/instrument after excitement for penetration or simply with external genitilia or with accessory Genital organs as mentioned above completes further stages of SEX where Ejaculation may or may not come avoiding need of any contraception to avoid pregnancy but needed to arrest spread of sexual transmitted disease like HIV,Syphlis,Gonorrhoea,Herpes,Hepatitis B & C ,etc.But in this Homosexual activity which is regarded as abnormal activity by many as it turned very purpose of SEX and human existence of Love for man and woman keeping our social fabrics intact also involves very intimate cooperation of both partners,here both partners are highly active members as lethargy or apathy of one partner cannot initiate this at all and this strong love,affection,intimacy,bondage and physical contact has lead to more increase in their numbers in society .
In modern time if SEX is not performed keeping intact all 04 stages of SEX with strong bondage affinity and adherence of both partners leads to breaking in relations or crimes where SEX is performed by male as simple formality of penetration after slight or full erection knowing nothing about arousal of opposite partner and ejaculation ,satisfication,pleasure,enjoyment is left behind or never asked or taken care of where female is always acts as passive receiver and Male as dominant partner serve as active partner without any question or liking of opposite partner or self realisation of failure covered under social dominance of male over female or a female even unsatisfied either gets satisfication by illegal means or remain unsatisfied but never asks or challenge male partner under social obligation of male dominance and even pay price of Infertility (being discarded by family or divorced ) even having her no fault.Sex can be performed in many style and ways with use of fragrance,sweet smelling scents,powders,lotions,jeelies,perfumes wearing alluring clothes or creating inductive environment like rose petal bathing,swimming or candle light meetings under flower shade ,exorbiant seducing music and video shows,dance with slight intake of stimulants and usual duration of 10-20 minutes(which may be increased in some one who practise its regularly) for stage II-IV performance is regarded as normal Sex ,regarding frequency 1-5 times a day to once a week or month is regarded as normal sex but if its frequency reached more or filthy means of using electric vibrators,binding partner with rods,chains or belts or stimulation by smoking ,alcohol or drugs or burning partners body parts or genitilia or Accessory Genitilia by cigratte butts or by pin pricks or electric or thermal currents is perversion and abnormal sex which comes as obesity hypertension,heart disease comes after over eating.Sex under intoxication of excessive cigarette,alcohol or drug is always perfomed of low category as performance is mostly un coordinated and incomplete,so it is better to avoid it.Enviornment personal privacy and isolation is important for good Sex performance as Sex is always a private personal matter in our society,no body wants its open and frank exhibition and show.and we have been matured in this way through our culture and social rules that sex has been always a private matter of a couple through which person and society both grow,sharing and swaping of partners or multiple partners or prostitutions or Jigglos cannot be termed as normal lawful practice of society and has been regarded as offence in Sex.In no way Sex promotes separations,loneliness ,breaking and divorces and it is not limited to simple enjoyment and satisfication burning and destroying our social fabrics involving two willingful compatible and legal partners .simple meeting and performance of these IV stages where social fabrics is destroyed canot be termed as normal sex.hence sex with animals like horse,dogs,cattles canot be termed as normal Sex,these should be avoided as damage to our external genitilia or body parts may occur as animals are not trained to perform sex with human beings and many sexual transmitted disease can spread through it.As in our many acivities like eating ,reading,sleeping,playing etc we do some time nothing ,some time excess and these are termed abnormal activities ,same way in Sex if we either do apathy or doesnot involve our partner or do which should not be done or praticed or do excess then it is called abnormal sex or perversion which brings many diseases as obesity after excessive eating and Anxiety nervosa after no eating.Sex with children,mentally retarded persons or under pressure against will of even a partner is termed rape and regarded as unabailable offence in our system.

Hence sex requires two active willing legal partners for its true performance,if partners are either excited by oneself or by simple stimulation of each other and a private suitable place and time is selected,Sex can be performed excellently without need of any counselling, advice ,medicine or artificial allurement environmental things as mentioned above.In society so many quack doctors or self styled sex specialist doctors or therapy are advertised in print,electronic and internet media claiming better and best Sex.Nothing like this actually exist,if both partners are really happy and pleasant a good sex has been performed irrespective of its total duration and duration of any stage mentioned above or overlapping of stages,it is a continous live processnot a machnary computer which will always move through stages by giving every stage a good time ,these stages has ben enumerated to uderstnd Sex in better way .if intimacy,adherence and closeness achieved in partners with Conception(reproduction) then Sex has fulfilled its target(reproduction is not necessary as mentioned above) and there is no role of any thing ,instrument,medicine,doctor,counselling or therapy .A rumor is spread regarding penis size,so many instruments,medicines or message oil or sold to increase its size but for a better performance of sex only 2-4 inch penis is enough as only outer 2inch of vagina is sensitive to penetration so such size odf penis will give pleasure to both man and woman and till today no convincing scientific medicines has been discovered which can increase penis size,thickness or tightening.No medicine or therapy has come which increase arousal or libido in male or female (Testosterone helps only those male who have got less its amount in Blood not in normal male where if it used may cause prostatic cancer or toother virilising effect)but so amny are sold in market for increasing desireness or lure for sex .Sex is a totally personal psychological matter which can be easily controlled and maintained by psychological counselling removing childhood fear,apprehension or any doubt about Sex as sex is painful,sex is crime,sex is abnormality,sex always result in pregnancy,sex is discarded things and sex is a formality to be performed after marriage in first night only and after that on demand by husband (wife has go no right to ask sex or question sex),limited sex after child births,no sex after menopause,no sex during menstruation ,no sexual discussion among family or with children or in school ,our external genitilia are dirty parts of waste disposable only so should be never cleaned or cared for.A good development has taken place in some patients of actual Erectile Dysfunction (ED) where Sildefinal or tadalfil gives good result but it has got no effect on many patients of ED too and in normal persons it never increases size or erection of penis but sold like anything and even female takes it where it has got no role ,same way for delayed ejaculation so many medicines and creams and injections are marketed which is better controlled by psychological counselling and gradual practise and learning style of performing sex under guidance of an expert.After unprotected sex to avoid pregnancy I-pill or unwanted 72 are sold openly in market which are nothing but high doses of oestrogen and progesterone which completely disturb a woman’s menstrual cycle and in many woman as suffering from migraine,thrombosis,hypertension,jaundice etc., they are contraindicated so government should ban selling of these drugs with harmful side effects by advertising in TV and printed media as youngsters are now developing live in relations and sexual activities openly with removal of fear of getting pregnancy but risk of developing sexual transmitted diseases like HIV,Gonorrhoea,herpes ,septic abortions and infertility.
DR.D.R.NAKIPURIA

09434143550
***Author is an expert Sex and HIV practitioner

Migraine is a serious type of Headache which occurs with so much robust type of headache mostly in one half of head with throbbing or pulsating type prececded by an aura or a smell or perception of some thing going to happen,blackspots in eye field,flickering movements of eye,face and hands or sensation of tingling type or numbness in head or any part of body preceded by nausea or vomiting feeling or vomiting and patient become very sensitive to light or sound needing a dark room and a noise less enviornment for soothing .This type of Headache is believed to be caused by extreme sensitivity of Blood Vessels and nerves to many chemicals and toxins yet to be discovered or many other physical agents like bad or unpleasant smell or flashing ,extreme cold or hot or un familiar enviornment any psychological insult like fear,apprehension,tension,anger,happiness or grief leading to contraction or dilatation of these blood vessels There is no cure or medications for migraine headache but the drugs can help reduce the frequency and severity of migraines.Migraine usually affects more female than male ,usually middleaged ladies are involved and subsides in intensity after menopause but seen too commonly in male too and involves children too.Migrain attack is severe one and usually last for 12-24 hrs but may last for 2-3 days and usually remission and recurrence are common ,mostly recurs in week or monthly wise but in some days it may occur at days interval.Usually it subsides normally without leaving any spot or complication like paressis or paralysis of any part or any defects in sensory or motor nerves of Body or any epileptic or any other type of slow or rapid movements or uncontrol of bowel and bladder or any type of para or sympathetic alterations.
There are many drugs specifically designed to treat migraine which are given below,some are drugs which abort or stops attack of Migraine once it has started like NSAIDs,Triptans,Ergot derivative,butabital,barbiturates,anxiolytic and sedative with opiates ,others are used to prevent its recurrance like B-Blockers,calcium channel blocker,Angiotensin receptor blockers,major tranquilisers and antivomiting medicines,anti epleptics,anti depressants,serotonin uptake or receptor inhibitors,anti histaminic like Cyprohepatidine,Botulinum and norepinephrine receptor or uptake inhibitors but still after their use recurrence is delayed but not completely inhibited.
Aborting drugs:-------These types of drugs are taken during migraine attacks and are designed to stop symptoms that have already begun. These are taken as soon as symptoms of a migraine occur. It may help if you take rest or sleep in a dark room after taking them.
Nonsteroidal anti-inflammatory drugs (NSAIDs):? Ibuprofen,Paracetamol or Aspirin or Diclofenac sodium or Acllofenac,Rafecoxib, Etorcoxic ,Naproxen,Indomethacin etc., may help relieve mild migraines.Combination of acetaminophen, aspirin and caffeine also may ease moderate migraines .Side effects: can lead to ulcers, gastrointestinal bleeding and rebound headaches.
Triptans: Both oral and injectable preparation even nasal spray is also available,Sumatriptan has been widely used rizatripan is showing promising result.
Used for severe migraine attacks.DRUGS ARE AS FOLLOWS:-Sumatriptan, rizatriptan ,Naratriptan, zolmitriptan, Almotriptan, frovatriptan and eletriptan .Side effects: nausea, dizziness and muscle weakness.They are not used in heart attack and stroke.
ERGOT DERIVATIVES:Used for pain lasting for more than 48 hours.DRUGS ARE'--- Ergotamine,Dihydroergotamine, Antivomiting or nauseating Medications if nausea or Vomiting present : Metoclopramide,prochlorperazine.
Butalbital:It is a sedative which is used in combination with other drugs for migraine attacks. Combination of butalbital with aspirin or acetaminophen Combination with caffine and codeine but rebound headache ,withdrwal symptoms.
OPIATES: Medicines containing narcotics, particularly codeine, are sometimes used to treat migraine pain when people can't take triptans or ergot.
Side effects: Habit-forming and patients are usually addicted.
Preventive medications:
These drugs are taken daily on a regular basis, to reduce the severity or frequency of migraines. Are used when two or more debilitating attacks a month occur and if pain-relieving medications aren't helping or symptoms include a prolonged aura or numbness and weakness.
Cardiovascular drugs:
Beta blockers: Commonly used to treat high blood pressure and coronary artery disease ? can reduce the frequency and severity of migraines.
Calcium channel blockers: Verapamil also may be helpful in preventing migraines and relieving symptoms from aura.
Antihypertensive medications: Lisinopril and candesartan are useful in reducing the length and severity of migraines..Side effects: Dizziness, drowsiness or lightheadedness.
Central Nervous System drugs:
Tricyclic antidepressants: Amitriptyline, nortriptyline and protriptyline .
Selective serotonin reuptake inhibitors (SSRIs) and serotonin and nor epinephrine reuptake inhibitors (SNRIs): Venlafaxine may be helpful in preventing migraine.
Anti-seizure drugs: Divalproex and Topiramate, and Gabapentin .Side effects: Nausea and vomiting, diarrhea, cramps, hair loss, and dizziness.
Major Tranqualisers : Trifluperazine,(Sibelium,no miraine)prochlorperazine(Stemetil).
Cyproheptadine: This antihistamine specifically affects serotonin activity. Doctors sometimes give it to children as a preventive measure.
Botulinum toxin type A: Botulinum toxin type A injections in mutiple sittings over head is sometimes used for treatment of chronic migraines,but relapses are common after 6-12 months of therapy.
Dr.D.R.Nakipuria
,09434143550