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Jul 23
Scientists decode monkey's brains
Scientists claimed to have decoded brain activity of monkeys as they were able to predict how two monkeys were planning to approach the same task differently even before they moved a muscle.

Scientists at Washington University in St Louis were able to decode brain activity while monkeys reached around an obstacle to touch a target.

Over the past 30 years, researchers have discovered that clear information can be obtained by decoding the activity of large populations of neurons.

The study published in the online edition of the journal Science demonstrated that multiple parameters can be embedded in the firing rate of a single neuron and that certain types of parameters are encoded only if they are needed to solve the task at hand.

They also discovered that the population vectors could reveal different planning strategies, allowing the scientists, in effect, to read the monkeys' minds.

It was a coincidence that the two monkeys chosen for the study had completely different cognitive styles. One was a hyperactive type, who kept jumping the gun, and the other was a smooth operator, who waited for the entire setup to be revealed before planning his next move, according to scientists.

The difference was clearly visible in their decoded brain activity. "That's what makes this really interesting," Daniel Moran from the School of Medicine at Washington University in St Louis, said.

Jul 21
India's children neither healthy nor happy: report
India fares poorly among middle-income countries when it comes to overall well-being of children even as the world witnessed significant progress in child health, education and nutrition during the last decade.

India has slipped by 12 ranks since 1995 and is placed 112th in the global "Child Development Index" released by Save the Children, the world's leading independent NGO that works for child rights.

According to the report, which analysed child well-being on three basic parameters of health, education and nutrition since 1995, India's CDI fell by three ranks from 100 to 103 between 1995 and 1999, and by another nine ranks (103 to 112) between 2005 and 2010. Out of 141 countries covered by the report, India is among the 14 whose ranks have dropped, it said.

"It is a wake-up call for India. Save the Children has reiterated economic progress must result in inclusive growth for all, especially the poor and the marginalised," said Thomas Chandy, CEO, Save the Children, India.

The CDI, launched in 2008 as a tool to monitor the progress in child well-being, ranks the best and worst places for children and improvements in child well-being globally.

It measures the number of children in school, under five mortality rates and number of underweight children. The three indicators are aggregated by simply calculating the average score between them for each period under review, meaning that each of them has equal weighting in the index scores.

According to the report, Japan is at present the best place in the world for a child, followed by Spain, Germany, Italy, France, Canada, Switzerland, UK and Norway.

The US is ranked 24 in the Index, while Australia is at 16th place and China is at 29th. Somalia is at the bottom.

The report also found that conditions for children have improved in 90 per cent of countries since the second half of the 1990s. Compared to that time, a child is now a third more likely to go to school and a third less likely to die before their fifth birthday.

However in stark contrast, it shows that nutrition is seriously lagging behind and that the proportion of acutely malnourished children grew by 1.2 per cent during the 2000s.

In India, 42 per cent of children are underweight, while 58 per cent are stunted by the age of two years.

Jul 21
Seven in 10 kids suffer from gum disease
Seventy per cent of children under 15 suffer from gum diseases, a nationwide survey found out. Conducted by the Indian Dental Association (IDA), it shows dental decay and oral cancer is rising among children.

Dentists say, dental hygiene in children is always neglected and overlooked as compared to lifestyle diseases like obesity and stress. The IDA surveyed 4 lakh children across India, as part of its community health initiative, and found 40% suffering from malocclusion (faulty jawline).

Dr PD Joshi, consultant dentist at Lilavati hospital, says, "At least 75-80% children come to me with cavity problems. Early cavities are leading to more and more children undergoing root canal." The procedure is difficult to do in children as their jaws are not properly formed, which leads to a prolonged treatment, he adds.

Dr Karishma Jaradi, aesthetic dentist, Dentzz dental care centres, said, "We see the dental problems depending on the age group. There's a rise in number of children in the 0-6 age group going for the root canal procedure. Cavities are mainly linked to not brushing the teeth properly after eating."

"Junk and sugary food items are the main culprits. Also, children tend not to pay much attention to oral hygiene. They wake up early for studies, and are in a hurry to leave for school. In their rush, brushing teeth properly takes a backseat," says Dr Ashok Dhoble, IDA secretary.

However, doctors say that dental problems among children are different in urban and rural areas. "In urban areas, we see more of cavity problems than oral cancer. In rural areas, it's the reverse. In a city like Mumbai children eat more of sugary products and junk food, while in rural areas, children start consuming tobacco products," says Joshi.

The IDA is now visiting schools and conducting interactive seminars to teach children the importance of oral hygiene. "Prevention is the best cure. Apart from brushing teeth twice, children should avoid eating chocolates and ice cream between meals," Dhoble says.

Jul 20
Why going to work on an egg is healthier than it used to be: Nutritional benefits have increased in
If you enjoy telling younger members of your family that food just isn't as wholesome as it used to be, you might need to make an exception.

Eggs are far more nutritious and beneficial for our health than they were 30 years ago, scientists claim.

Not only have they found that eggs are lower in fat, cholesterol and calories, but they also contain more vitamin D than previously thought.

A major study, funded by the Department of Health, found that the average medium-sized egg now has nearly 25 per cent less saturated fat which is linked to heart disease than one sold in the 1980s.

They contain 1.3 grams, rather than 1.7 grams. We are advised to eat no more than 20 grams of saturated fat a day.

The study also found they contain 177 micrograms of cholesterol, the substance which clogs arteries, just over 10 per cent less than the 202 micrograms previously recorded. They have fewer calories than experts originally thought, too there are 66 in a medium egg, not 78.

Furthermore, the scientists said eggs contain nearly twice the amount of vitamin D than was noted in the 1980s.

The vitamin is essential for protecting the bones and preventing rickets, a condition which causes bone deformities in young children.

But earlier this year the chief medical officer, Dame Sally Davies, warned that many of us are not getting enough of it. Cases of rickets have increased fivefold since 1997.

A medium egg contains 1.6 micrograms of vitamin D compared with the 0.9 micrograms that was recorded in the 1980s. This is two-thirds of our recommended daily amount.

Nutritionist Cath MacDonald said: 'This is a very welcome finding at a time when there is rapidly accumulating evidence that a lack of vitamin D could be a risk factor for a number of chronic diseases.'

Scientists from the Institute of Food Research believe eggs are healthier largely because the food given to hens has changed.

Since the 1980s they have been fed a mixture of wheat, corn, vegetable oil and high-protein formulated feed, rather than meat and bone-meal.

This means their eggs have less cholesterol and saturated fat. The new feed also helps them to absorb more vitamin D and other nutrients

Better technology also means scientists can now analyse the nutritional content of eggs more accurately. Previous measurements may have overestimated fat and cholesterol levels.

Jul 20
Bryologs could flush out HIV
The compound, derived from the bryozoan Bugula neritina, a tiny marine organism, could activate latent pockets of the virus that make the disease almost impossible to eradicate, according to researchers at UCLA. Current HIV treatment with antiretrovirals are expensive and require a demanding drug regimen that only affects the active HIV, not the dormant virus found within T-cells. Scientists hope the discovery will lead to a cure for HIV, and possibly for treating cancer and Alzheimer's disease too.

Jul 19
Cannabis use doubles risk of premature birth
Women who use marijuana can more than double the risk of giving birth to a baby prematurely, a new study has revealed.

Preterm or premature birth - at least three weeks before a baby's due date - can result in serious and life-threatening health problems for the baby, and an increased risk of health problems in later life, such as heart disease and diabetes.

A large international study, of more than 3000 pregnant women in Adelaide, Australia and Auckland, New Zealand has detailed the most common risk factors for preterm birth.

The research team, led by Professor Gus Dekker from the University of Adelaide's Robinson Institute and the Lyell McEwin Hospital, found a number of risks for spontaneous preterm birth.

These risks include strong family history of low birth weight babies, use of marijuana prior to pregnancy, having a mother with a history of pre-eclampsia, having a history of vaginal bleeds and having a mother with diabetes type 1 or 2.

The team also found that the greatest risk factors involved in the preterm rupture of membranes leading to birth included mild hypertension not requiring treatment, family history of recurrent gestational diabetes, receiving some forms of hormonal fertility treatment and having a body mass index of less than 20.

"Our study has found that the risk factors for both forms of preterm birth vary greatly, with a wide variety of health conditions and histories impacting on preterm birth," Professor Dekker, who is the lead author of the study, said.

"Better understanding the risk factors involved in preterm birth moves us another step forward in potentially developing a test - genetic or otherwise - that will help us to predict with greater accuracy the risk of preterm birth. Our ultimate aim is to safeguard the lives of babies and their health in the longer term," he added.

Jul 19
Inactivity 'killing as many as smoking'
A lack of exercise is now causing as many deaths as smoking across the world, a study suggests.

The report, published in the Lancet to coincide with the build-up to the Olympics, estimates that about a third of adults are not doing enough physical activity, causing 5.3m deaths a year.

That equates to about one in 10 deaths from diseases such as heart disease, diabetes and breast and colon cancer.

Researchers said the problem was now so bad it should be treated as a pandemic.

And they said tackling it required a new way of thinking, suggesting the public needed to be warned about the dangers of inactivity rather than just reminded of the benefits of being active.

The team of 33 researchers drawn from centres across the world also said governments needed to look at ways to make physical activity more convenient, affordable and safer.

It is recommended that adults do 150 minutes of moderate exercise, such as brisk walking, cycling or gardening, each week.

The Lancet study found people in higher income countries were the least active with those in the UK among the worst, as nearly two-thirds of adults were judged not to be doing enough.

The researchers admitted comparisons between countries were difficult because the way activity was estimated may have differed from place to place.

Nonetheless, they said they remained confident that their overall conclusion was valid.

Pedro Hallal, one of the lead researchers, said: "With the upcoming 2012 Olympic Games, sport and physical activity will attract tremendous worldwide attention.

"Although the world will be watching elite athletes from many countries compete in sporting events... most spectators will be quite inactive.

"The global challenge is clear - make physical activity a public health priority throughout the world to improve health and reduce the burden of disease."

Prof Lindsey Davies, president of the UK Faculty of Public Health, agreed.

"We need to do all we can to make it easy for people to look after their health and get active as part of their daily lives," she said.

"Our environment has a significant part to play. For example, people who feel unsafe in their local park will be less likely to use it."

But others questioned equating smoking with inactivity.

While smoking and inactivity kill a similar number of people, smoking rates are much lower than the number of inactive people, making smoking more risky to the individual.

Dr Claire Knight, of Cancer Research UK, said: "When it comes to preventing cancer, stopping smoking is by far the most important thing you can do."

Jul 18
Physical Inactivity May Be as Deadly as Smoking
Not moving enough may be as hazardous to your health as smoking, a new study shows.

The study, which is published in The Lancet, estimates as many as 5.3 million deaths around the world were caused by physical inactivity in 2008.

By comparison, researchers point out that cigarette smoking is estimated to cause about 5 million deaths worldwide each year.

"Physical inactivity has a large impact on the health of the world. In fact, its impact is comparable to that of cigarette smoking," says researcher I-Min Lee, ScD, an epidemiologist at the Harvard School of Public Health, in a news conference.

Experts who were not involved in the research questioned that claim, however.

Timothy Armstrong, PhD, coordinator of the surveillance and population-based prevention program for the World Health Organization (WHO) in Geneva, Switzerland, points out that his organization estimates that inactivity causes fewer deaths -- about 3.2 million deaths around the world each year.

Armstrong says he thinks the Lancet researchers compared numbers that were arrived at in two different ways. "If the same methodology had been applied to smoking, I suspect we would not see the similar estimates for mortality," Armstrong says in an email to WebMD.

"That is not to say that physical activity or physical inactivity is not a major risk factor" for chronic diseases, he says. "It is. WHO currently ranks it fourth after high blood pressure, tobacco use, and high cholesterol."

The study further estimates that 6% of heart disease, 7% of type 2 diabetes, and about 10% of colon and breast cancers, are linked to lack of activity.
Sitting a Lot Can Be 'Very Bad' for You

Experts who study the health effects of physical inactivity praised the study for its broad scope and careful methods.

"This is a super, super analysis," says James Levine, MD, PhD, professor of medicine at the Mayo Clinic in Rochester, Minn. "We know that as soon as somebody gets out of their chair, their blood sugar improves, their blood cholesterol and triglycerides improve, and that's very consistent. Every time you get up it gets better. Every time you sit down it gets worse."

"If you add up the fact that you sit a lot, many, many hours each day, the cumulative impact of a lot of sitting is not surprisingly therefore very bad," Levine says.

Other experts agree.

"Inactivity plays a role in almost every chronic disease there is," says John P. Thyfault, PhD, associate professor of nutrition and exercise physiology at the University of Missouri's School of Medicine. He studies the health effects of inactivity but was not involved in the research.

"We should maintain cigarette smoking as public health enemy number one, but we should move physical inactivity right up next to it," he says.

Jul 18
Anti-ageing pills closer to reality
A pill that alleviates the worst aspects of ageing could be closer than we think, an expert says.

In fact, a drug already licensed to treat cancer is getting the results scientists are after, in animals.

Professor Dame Linda Partridge, the director of the Institute of Ageing at University College London, said that when mice were fed the drug rapamycin, they lived longer, the Age reported.

But the drug also offered protection against neurodegenerative diseases, which are closely linked to ageing.

"Ageing is the main risk factor for all these horrible killer and chronic conditions dementia, cardiovascular disease, cancer," Professor Partridge said.

"What we are trying to do here is hit the underlying ageing process itself through understanding mechanisms to protect against all these things at once, rather than treating them piecemeal.

"Rapamycin is beginning to look like a proof of principle that that kind of approach is going to work.

However, the drug a natural product initially discovered in the soil of Easter Island is also believed to have a downside.

It's an immune suppressant and is also used to prevent the body rejecting an organ after transplant.

But there's potential to boost the drug's health benefits while minimising its undesirable side-effects, Professor Partridge said.

Professor Partridge will deliver the 2012 Graeme Clark Oration in Melbourne tomorrow.

Jul 17
Heavy snoring doubles arthritis risk
Snoring heavily almost doubles the risk of developing rheumatoid arthritis, a study shows.

Researchers in Taiwan found patients diagnosed with the snoring-related condition sleep apnoea were nearly twice as likely to suffer the joint-damaging disease, Daily Mail reported Thursday.


Scientists believe chronic sleep apnoea can lead to inflammation in blood vessels in the body, which may act as a catalyst for arthritis.

Rheumatoid arthritis was previously thought to be triggered when something goes wrong with the immune system.

In Britain, three million people suffer from sleep apnoea, though many more may remain undiagnosed.

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