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Jun 07
Alcohol can trigger dangerous palpitations
"Holiday heart syndrome," first coined in 1978, refers to patients who experience a potentially dangerous form of palpitation after excessive drinking, especially during winter holidays. The symptoms usually went away when revellers ceased drinking.

Research from University of California San Francisco, builds on that finding, establishing a stronger causal link between alcohol consumption and serious palpitations in patients with atrial fibrillation, the most common form of arrhythmia (erratic heartbeats).

California researchers report that people with atrial fibrillation had almost a four and a half times greater chance of having an episode if they were consuming alcohol than if they were not, the American Journal of Cardiology reports.

"One of the remaining big unknowns is why or how this happens," said senior author Gregory Marcus, assistant professor of medicine at California, according to a California statement.

In the study, conducted from September 2004 to March 2011, researchers interviewed 223 patients with documented cardiac arrhythmia. They asked patients: "Does alcohol trigger your heart palpitations?" Participants ranked their symptoms on a scale from one to five (ie never, rarely, sometimes, frequently, and always).

"We defined 'yes' as frequently or always versus the rest of the responses," Marcus said, "and found that, after adjusting for potential confounders, atrial fibrillation patients had statistically significant greater odds of reporting that alcohol would trigger their symptoms."

The mean age of the study participants was 59 years. Eighty per cent were Caucasian; 11 per cent were Asian; five per cent Latino, and four per cent declined to state their ethnicity in the atrial fibrillation group.

Jun 06
Secrets of zebra fish's self-healing ability unlocked
Scientists claim to have unlocked the secrets of the zebra fish's remarkable ability to heal its spinal cord after injury, in a study which they say could lead to new effective therapies for paralysis patients.

Researchers at the Monash University in Australia found a protein, called fibroblast growth factor (fgf), plays a major role in the fish's amazing self-healing ability.

The findings, published in The Journal of Neuroscience, could eventually lead to new ways to stimulate spinal cord regeneration in humans, the researchers said.
Professor Peter Currie, who led the research, said when the spinal cord is severed in humans and other mammals, the immune system kicks in, activating specialised cells called glia to prevent bleeding into it.

"Glia are the workmen of nervous system. The glia proliferate, forming bigger cells that span the wound site in order to prevent bleeding into it. They come in and try to sort out problems. A glial scar forms," Prof Currie said in a statement.

However, the scar prevents axons, threadlike structures of nerve cells that carry impulses to the brain, of neighbouring nerve cells from penetrating the wound. The result is paralysis.

"The axons upstream and downstream of the lesion sites are never able to penetrate the glial scar to reform. This is a major barrier in mammalian spinal cord regeneration," Prof Currie said.

In contrast, the zebra fish glia form a bridge that spans the injury site but allow the penetration of axons into it.

The fish can fully regenerate its spinal cord within two months of injury. "You can't tell there's been any wound at all," Prof Currie said.

The scientists found that fgf controlled the shape of the glia, and accounted for the difference in the response to spinal cord injury between humans and zebra fish.

The study shows the protein could be manipulated in the zebra fish to speed up tissue repair even more, they said.

"The hope is that fgf could eventually be used to promote better results in spinal cord repair in people," Prof Currie added.

Jun 06
'Female' gene to blame for migraines - which may explain why women are more prone than men
A 'female' gene may be to blame for migraine - explaining why women are more likely to suffer from the debilitating headaches, research shows.

A study found a new region on the X chromosome as having a link to migraines, providing new evidence their might be a 'susceptibility' gene involved.

All women have two X chromosomes while men have an X and a Y chromosome.

Researchers, led by Lyn Griffiths from Australia's Griffith University, say more than one X chromosomal gene may be involved and believe a gene involved in iron regulation in the brain merits further attention.

Professor Griffiths based her study on genetic research of 300 inhabitants of remote Norfolk Isand, between Australia and New Zealand.

Many of the islanders are descended from survivors of the mutiny on the Bounty, moving there when they outgrown Pitcairn Island.

Eighty per cent of the inhabitants can trace their ancestry back to the mutiny.

Prof Griffiths said: 'These results provide more support for the role of the X chromosome in migraine and may explain why so many more females suffer from the disorder.

'Currently, 12 per cent of the population suffers from migraine. Even though we have some very good treatments for this very debilitating disease, they certainly don't work for everyone and can have some adverse side effects.

'Hence there is a real need to develop new migraine treatments.'

Prof Griffiths added that the island was ideal for study purpose because the relatively small gene pool made mapping genetics easily.

She said: 'This population was used due to its unusual pedigree structure in which genetic relationships can be traced through genealogical data to the island's original founders, and also the high incidence of migraine sufferers in this population.

'It's very useful for gene mapping purposes because of the reduced genetic and environmental diversity.'

The university research was funded by Australia's National Health and Medical Research Council.

Jun 05
19 children dead due to mysterious fever in Bihar
Around 19 children have died and 16 others were undergoing treatment in hospitals due to outbreak of a mysterious fever in Bihar's Gaya and Muzaffarpur districts in the past fortnight, official sources said on Monday.

Eight children have died in the ANMCH hospital in Gaya and six others were hospitalised, ANMCH Superintendent Dr Sitaram Prasad said.

In Muzaffurpur district, 10 children have died due to mysterious fever and eight others were undergoing treatment at Kejriwal Hospital since the past fortnight, its director B B Giri said. One child died in the SKMCH in Muzaffarpur, while two others were admitted with symptoms of the fever at the hospital, the sources said.

The two districts had witnessed outbreak of the mysterious fever last year too in which over 100 children had died.

Jun 05
Raisin snack cuts excessive calorie intake and promotes satiety in kids
Eating raisins as an after-school snack prevents excessive calorie intake and increases satiety or feeling of fullness as compared to other commonly consumed snacks, a new study has suggested.

The study, funded by a grant from the California Raisin Marketing Board, was conducted among 26 normal-weight boys and girls ages 8 11 during a three-month timeframe.

Study participants were randomly assigned to eat raisins or other snacks, including grapes, potato chips or chocolate chip cookies, until they were comfortably full.

Additionally, each child received the same standardized breakfast, morning snack and lunch on test days. Subjective appetite was measured before and immediately after snack consumption at 15-minute intervals.

The result showed that food intake following raisin consumption was lower and satiation greater compared to the other snacks.

When eating raisins, children consumed significantly fewer calories when compared to the other snacks in the study.
Grapes, potato chips and cookies resulted in approximately 56 percent, 70 percent and 108 percent higher calorie intake compared to raisins, respectively.

Cumulative calorie intake (breakfast + morning snack + lunch + after-school snack) was 10 percent 19 percent lower after raisins compared to other snacks.

Although all snacks reduced subjective appetite, desire-to-eat was lowest after consuming raisins.

The study was conducted by lead researcher, G. Harvey Anderson, Ph.D., Professor of Nutritional Sciences and Physiology, Department of Nutritional Sciences, University of Toronto and co-investigated by Nick Bellissimo, Ph.D., Assistant Professor, School of Nutrition, Ryerson University and Bohdan Luhovyy, Ph.D., Assistant Professor, Department of Applied Human Nutrition, Mount Saint Vincent University.

"To our knowledge, this is the first controlled study that looks at after-school snacking and satiety among children," said Anderson.

"We found consumption of raisins as a snack prevented excessive calorie intake, increased the feeling of fullness, and thereby may help contribute to the maintenance of a healthy weight in school-age children," he added.

Jun 04
Drinking plain water instead of fizzy drinks and fruit juice 'lowers the risk of women developin
Women who choose plain water over sweet fizzy drinks or fruit juice, have a lower risk of developing diabetes.

Replacing sweet drinks with water could help stave off the metabolic disorder, according to researchers at the Harvard School of Public Health.

But adding water to the sugary beverages a person consumes throughout the day won't make a difference, they said.

The results are based on the drinking habits of 83,000 women followed for more than a decade.

Lead researcher Dr Frank Hu said it is well established that sugary beverages are bad for diabetes risk.

People have recommended drinking plain water instead of sugar-sweetened beverages, he said, 'and the question is whether this kind of substitution has any impact on diabetes'.

Dr Hu and his team collected data from the massive Nurses Health Study, which tracked the health and lifestyle of tens of thousands of women across the U.S.

The study included 82,902 women who answered questions about their diet and health over a 12-year span.

Over time, about 2,700 of them developed diabetes.

The amount of water women drank did not seem to influence their diabetes risk - those who drank more than six cups a day had the same risk as women who drank less than one cup a day.

However, sugar-sweetened drinks and fruit juice were tied to a higher risk of diabetes - about 10 per cent higher for each cup consumed each day.

The research team estimated that if women replaced one cup of fizzy drink or fruit juice with one cup of plain water, their diabetes risk would fall by 7 or 8 per cent.

While it is not a huge reduction in the risk, 'because diabetes is so prevalent in our society, even 7 or 8 per cent reduction in diabetes risk is quite substantial in terms of the population,' Dr Hu said.

About 10 per cent of women, or 12.6million, have diabetes in the U.S.

A 7 per cent reduction would mean that instead of ten out of every 100 women having diabetes, the number would be closer to nine out of every 100.

Dr Hu's study, published in the American Journal of Clinical Nutrition, also found that unsweetened coffee or tea might be a good alternative to sugary beverages.

The researchers estimated that replacing one cup of a carbonated drink or fruit juice with one cup of coffee or tea could reduce the risk of developing diabetes by 12 to 17 per cent.

Dr Hu said the study is important in pointing out that fruit juice is not an optimal substitute for soda or other sugar-sweetened drinks.

He said: 'The reality is those juices contain the same amount of calories and sugar as soft drinks.'

The bottom line, he said, is that plain water is one of the best calorie-free choices for drinks, and 'if the water is too plain, you can add a squeeze of lemon or lime'.

Dr Barry Popkin, a professor at the University of North Carolina School of Public Health who was not involved in the study, said: 'It is essentially not that water helps, except with hydration, but that the others hurt.'

Jun 04
Study: Women who smoke give birth to lighter babies
Women who smoke during pregnancy give birth to lighter and smaller babies, says a Spanish study.

The findings were borne out by research conducted by the University of Zaragoza in Spain on 1,216 newly born babies.

Such babies were between 180 and 230 grams thinner than the offspring of non-smoking mothers, which averages 216 grams, the journal Early Human Development reports.

Furthermore, subcutaneous (below the skin) skinfolds, which show the amount of fat, are lower in children born of mothers who smoked, according to a Zaragoza statement.

"Given the scarce bibliography on the subject, we had to assess the impact of tobacco on the body composition of babies born to mothers who smoked during pregnancy," Gerardo Rodriguez from Zaragoza who led the study, told SINC, Spain's public scientific information service.

The experts analysed the newly-born full-term babies with a gestational age of 37 weeks of 1,216 mothers (22.1 percent of whom smoked an average of eight cigarettes daily) at the University Clinical Hospital.

The children of those mothers who had admitted to consuming alcohol or taking illegal drugs during pregnancy were excluded from the study.

Jun 02
Cancer Incidence May Surge 75% by 2030, Lancet Says
The global incidence of cancer may rise more than 75 percent by 2030, led by developing countries, according to research published today in the Lancet journal.

The number of people with cancer in 2030 may rise to 22.2 million, or 0.3 percent of the global population, from 12.7 million in 2008, according to research led by Freddie Bray of the International Agency for Research on Cancer in Lyon, France. The projection is based on the United Nations's population forecast, the IARC's database tracking cancer incidence in 184 countries and expected increases in the rates of colorectal, female breast, prostate and, in high-income countries, lung cancer in women.

While improving living standards in lower-income countries may lead to a decrease in infection-related cancers such as cervical and stomach cancer, that may be offset by a surge in the types of cancer associated with smoking, obesity and diet which currently affect mainly richer countries. Poor countries, as measured by the UN's Human Development Index, may see a doubling in the incidence of cancer to 490,000 in 2030 from 2008, according to the study.

"This study underscores the diversity of cancer as a worldwide occurrence and the extent to which the disease patterns differ from country to country," the authors said in the article. Targeted interventions are needed to "effectively control the prevalence of lifestyle factors including tobacco avoidance and cessation of smoking, a reduction in alcohol consumption and obesity, and the promotion of increased levels of physical activity."

The richest countries currently bear much of the cancer burden, with almost 40 percent of the global incidence occurring in these countries, while having only 15 percent of the world's population. The most commonly diagnosed cancers in these areas are colorectal, lung, female breast, prostate and stomach.

Jun 02
Dengue scare rocks city
On Wednesday night an SMS that started in media circles went viral 'First dengue death in Chennai. Manjula (29) d/o Kasinathan died due to dengue. She was admitted in KHM Hospital in Anna Nagar,' it read. While it turned out that the woman tested negative for the disease post-mortem, word had got out and caused a mini panic. Courtesy the widespread news about 34 dengue deaths indicating an epidemic in the Tirunelveli-Tuticorin belt, people were understandably afraid. "We have run out of mosquito repellant and coils in the last two days. People have begun purchasing two and three mosquito nets, like they're going to war," said the store manager of a retail supermarket in Anna Nagar. While mosquito quelling measures are very much in vogue during a regular Chennai summer, this time the scare has taken things a little further.

Astonishingly, it is only after the deaths in Tirunelveli began to make news that people began taking dengue seriously. Even AH1N1 (swine flu) caused a massive panic in April when cases began cropping up and the total number of people affected this year in Chennai is just over 100. In comparison dengue has been silently consistent with over 131 cases being reported this year alone. "As long as the fatalities are few and far between, people don't take it seriously. Now that dengue is spreading quickly people with a fever and rash are crowding our OP wards," said an administrator at Stanley Medical College and Hospital. And almost as if on cue, doctors in private hospitals that Express spoke to admitted that in the last week people have been bringing in their children as soon as they break out with a rash or are mildly warm. "They come into the ER and ask us to save the child from dengue," said a doctor at a private hospital in south Chennai, "But we actually encountered two kids with dengue through this, so I suppose it's good in a way to be paranoid," he said.

Experts in the field of infection control have said that corrective measures like repellants aren't the best way to keep dengue at bay. "It's all in the water," said Ram Gopalakrishnan, infectious disease physician, Apollo Hospitals. "People do not understand that unlike malarial vector mosquitoes, the species that carries dengue can live and lay eggs in small puddles of water," he explained. Though it may look absolutely innocent, a simple puddle of water, a bucket left half full in the toilet or a little extra water in a flower pot can become a breeding ground for these winged terrors. "They have adapted to multiply and live in urban conglomerate areas. They don't really need large puddles on the road or dirty canals to complete their life cycle," he said.

Though the serotype-3 of the virus, the fatal strain that has been detected down south, has not yet made its way to the underbelly of Chennai's mosquito populace, perhaps these periods of panic will help to keep people on their toes in these times, "Less than one per cent of dengue cases are fatal, but when that one per cent makes takes such a huge toll, there's no harm in taking an extra cautious step," he concluded.

Jun 01
Bananas vs. sports drinks: what's better?
When it comes to the optimal mid-workout energy boost, how do bananas measure up against sports performance drinks? A recent study shows that the humble yellow fruit holds its own, as long as you don't mind the bloat.

The study, which appeared earlier this month in the peer-reviewed
journal PLoS ONE, pitted bananas against a typical 6 percent carbohydrate sports drink while 14 well-trained cyclists performed a 75-kilometer time trial.

Each cyclist completed two time trials while consuming 0.2 grams of carbohydrate per kilogram of body weight every 15 minutes. In one time trial, the carbohydrates came from bananas, and in the other, they came from a sports drink.

The riders who ate bananas reported feeling more full and bloated, yet their blood glucose levels and performance did not differ between the two time trials.

If you're looking for other low-cost energy boosters, Runners World magazine recommends packets of jelly or honey, or even candy, raisins, or pretzels -- when taken with water, these modest foods work just as well as pricier energy bars and gels during your longer runs or rides.

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