World's first medical networking and resource portal

News & Highlights
Please make use of the search function to browse preferred content
Medical News & Updates
Sep 09
Spinal manipulation relieves back pain for some, study says
Manipulating the spine can help people with lower back pain - but it doesn't work for everyone, according to a new study.

Spinal manipulation, or applying force to the joints of the spine, is a technique commonly used by chiropractors and physical therapists, according to the National Center for Complementary and Integrative Health. However, there is conflicting evidence about whether the treatment actually helps people, the researchers wrote in their study.

In the new study, the researchers found that spinal manipulation therapy (SMT) provided relief for some patients with lower back pain, but not for others. [5 Surprising Facts About Pain]

"The big finding is that both sides have been right all along," said Greg Kawchuk, a professor of rehabilitation medicine at the University of Alberta and co-author of the study. It's not a matter of whether the treatment works or doesn't work, but rather, figuring out the best way to care for each patient, he said.

In the study, 32 people with lower back pain received two spinal manipulation treatments over the course of a week. They told researchers how much pain they felt, and the researchers also looked at objective measures of improvement, including measurements of muscle activity, disc hydration and spinal stiffness. A control group of 16 people underwent similar physical examinations, but did not receive treatment. A third group, of 59 people who did not have back pain, was also included, to provide another comparison.

Among the participants who underwent the spinal manipulation treatments, 15 said that they felt better, and the researchers found that their physical measurements all improved as well, Kawchuk told Live Science. For example, their measurements of disc hydration and spinal stiffness were nearing those of the people without any back pain at the end of the study, he said.

The people who said they did not feel any better did not have those physical changes, Kawchuk said.

It's unclear why the treatment worked for some patients but not others, but one idea is that the people who felt that the treatment worked have different spinal characteristics, Kawchuk said. The researchers need to do a much larger study to see whether that may be the case, he added.

The new study "is the beginning of an attempt to understand why some patients respond to SMT and others do not," said Dr. Allyson Shrikhande, a rehabilitation physician at Lenox Hill Hospital in New York City, who was not involved with the study.

Previous studies have looked at how SMT can affect people's pain levels and degree of disability, but they didn't include the physical measurements, Shrikhande told Live Science in an email.

She added that it would have also been beneficial if the researchers had examined how the treatment affected patient's hamstring flexibility, because this can significantly affect people's bodies.

For the people who were not helped by the spinal manipulation treatments, it's not all bad news.

Future research will be aimed at figuring out what does work for these people, such as massage or surgery, Kawchuk said. The ultimate goal is to be able to match patients with the treatments that work best for them, he said.

"Back pain is not one problem - it's a group of problems," so there won't be one treatment that works for everyone, Kawchuk said.

The study was published on Aug. 31 in the journal Spine.

Sep 07
Novel genes found in gut disease under age five
Researchers analysing the complicated genetic influences in inflammatory bowel disease (IBD) have discovered new gene variants associated with an often-severe type of the disease that affects children under the age of five.

"As we continue to understand the specific functions of these genes in this type of childhood-onset disease, we are working to design more effective therapies," said study leader Judith Kelsen from The Children's Hospital of Philadelphia (CHOP), US.

Inflammatory bowel disease (IBD) is a painful, chronic inflammation of the gastrointestinal tract.

In fact, very early-onset IBD (VEO-IBD), diagnosed under age five, is often more severe than IBD that starts later in childhood.

"There has been extensive research in the genes contributing to adult-onset IBD and in children aged 10 and older but relatively little research has been performed in the very-early onset subtype of the disease," Kelsen said.

The study team analysed DNA from 125 children with VEO-IBD, all of them under age four, along with DNA from 19 of their parents.

A control group of 210 participants included 145 healthy individuals, 45 patients with pediatric IBD and 20 with adult-onset Crohn's disease (one of the two major types of IBD).

The researchers found rare and novel variants in genes that regulate B-cells and T-cells -- immune cells with important roles in immunodeficiency disorders.

They also discovered rare variants in the IL10RA gene, a member of a key immune function pathway.

The findings were published online in the journal Gastroenterology.

Sep 04
Blueberry extract could treat gum infection
Scientists have discovered that wild blueberry extracts help prevent dental plaque formation and treat severe gum diseases.

The findings could lead to reduced use of antibiotics to treat the serious gum infection disease called periodontitis.

The researchers from Laval University in Quebec City, Canada, said they were developing an oral device that could slowly release the blueberry extract after deep cleaning to help treat periodontitis.

Gum disease is a common condition among adults that occurs when bacteria form biofilms or plaques on teeth, and consequently the gums become inflamed.

Many people have had some degree of gum inflammation, or gingivitis, caused by dental plaque. The gums get red and swollen, and they bleed easily.

If left unchecked, the condition can progress to periodontitis. The plaque hardens into tartar, and the infection can spread below the gum line and destroy the tissue supporting the teeth.

To treat this condition, dentists scrape off the tartar and sometimes have to resort to conventional antibiotics.

But recently researchers have started looking at natural antibacterial compounds to treat gum disease.

Daniel Grenier and colleagues from Laval University wanted to see if blueberry polyphenols, which work against foodborne pathogens, could also help fight Fusobacterium nucleatum, one of the main species of bacteria associated with periodontitis.

In the lab, the researchers tested extracts from the wild blueberry against F. nucleatum.

The polyphenol-rich extracts successfully inhibited the growth of F. nucleatum, as well as its ability to form biofilms.

It also blocked a molecular pathway involved in inflammation, a key part of gum disease.

The findings were reported in the Journal of Agricultural and Food Chemistry.

Sep 03
Vitamin A linked to alcoholic liver disease development
Counteracting alcohol's effect on vitamin A levels in the liver may lead to novel treatments for alcoholic liver disease, suggests new research.

In particular, the research found that chronic alcohol consumption has a dramatic effect on the way the body handles vitamin A.

Long-term drinking lowers vitamin A levels in the liver, which is the main site of alcohol breakdown and vitamin A storage, while raising vitamin A levels in many other tissues.

"We hope this study will lead to a broader understanding and appreciation of the fact that excessive consumption of alcohol has a negative effect on vitamin A function in the body," said one of the researchers Robin Clugston from Columbia University Medical Center in New York, New York.

"Ultimately, we hope that vitamin A will be seen as a broad target for alcohol in multiple tissues of the body and that our understanding of alcohol-induced disease will be linked together by its effects on vitamin A," Clugston noted.

Clugston and colleagues conducted multiple experiments using several groups of mice including those who received alcohol-containing food and alcohol-free food.

They analysed the liver and other organs (kidney, spleen, heart, lung, white adipose, brown adipose and blood), from both groups of mice and measured tissue vitamin A levels.

The alcohol-fed mice had distinct changes in how their body handled vitamin A. In general, vitamin A levels were lower in the liver and higher in other tissues.

This strongly suggests that vitamin A in the liver is reduced by excessive alcohol consumption and that these findings are important in the development of alcoholic liver disease.

The findings appeared in the FASEB Journal.

Sep 02
Vehicular air pollution increases heart attack risk
Even short term exposure to particulate matter and nitric dioxide (NO2) air pollution, that originate predominantly from the combustion of fossil fuels such as emissions from industrial plants or vehicles increases risk of severe heart attacks, research has found.

The study investigated the effect of short term exposure to air pollution on the risk of ST-segment elevation myocardial infarction (STEMI), a deadly type of heart attack caused by a prolonged blockage of blood supply in the heart.

"The association between STEMI and air pollution was observed within one day of exposure," said researcher Jean-Francois Argacha, cardiologist at University Hospital Brussels in Belgium.

"This was despite the fact that concentrations of air pollutants were within the European air quality standard," Argacha noted.

The researchers used a statistical model to evaluate real-time exposure to air pollution in each part of Belgium with adjustments for population density.

The researchers looked at records of hospitalisations for STEMI in Belgium between 2009 and 2013.

They found that 10 micrograms per cubic metre increases in ambient PM2.5 concentrations were associated with a 2.8 percent increase in STEMI while 10 micrograms per cubic metre rises in NO2 were associated with a 5.1 percent increased risk.

These associations were only observed in men.

"It is possible that only men were affected because of the under representation of women in our study population (less than 25 percent)," Argacha said.

The findings were presented at European Society of Cardiology (ESC) Congress 2015 in London this week.

Sep 01
Develop close friendships to stay fit
Developing close friendships early in life may help children stay physically fit later in their adulthood, suggests new research.

"These results indicate that remaining close to -- as opposed to separating oneself -- from the peer pack in adolescence has long-term implications for adult physical health," said one of the researchers Joseph Allen from University of Virginia in the US.

"In this study, it was a robust predictor of increased long-term physical health quality," Allen noted.

The findings indicate that adolescent relationship qualities may come to influence adult health through decreased levels of later anxiety and depressive symptoms.

The researchers recruited a diverse group of 171 seventh- and eighth-graders and followed them from ages 13 through 27 years old.

From ages 13 through 17, the participants' best friend filled out a questionnaire assessing the overall quality of the friendship, including the degree of trust, communication, and alienation in the relationship.

Friends also provided information about how much participants' focused on fitting in with their peers.

Participants' health quality was then assessed annually at ages 25, 26, and 27 years old with questions about their overall health, anxiety and depression symptoms, and body mass index.

Results indicated that both high-quality close friendships and a drive to fit in with peers in adolescence were associated with better health at age 27.

The study was published in the journal Psychological Science.

Aug 31
Eating raw oysters ups risk of norovirus infection
Eating raw oysters and shellfish may increase the risk of getting infected by human norovirus that causes stomach pain, diarrhoea, nausea and vomiting, a study says.

Oysters not only transmit human norovirus but also serve as a major reservoir for these pathogens, the findings show.

"More than 80 percent of human norovirus genotypes were detected in oyster samples or oyster-related outbreaks," said author Yongjie Wang, professor at the Shanghai Ocean University in Shanghai.

"The results highlight oysters' important role in the persistence of norovirus in the environment, and its transmission to humans. They demonstrate the need for surveillance of human norovirus in oyster samples," Wang said.

In earlier research, the examiners found that 90 percent of human norovirus sequences in China came from coastal regions.

The current research said the same is true all over the world, except in tropical regions.

Oysters's status as vectors for human norovirus transmission is likely abetted by their presence in coastal waters, which are frequently contaminated by human waste, Wang said.

Previous research says noroviruses can persist for weeks in oyster tissues, and commercial depuration fails to expunge them.

Wang advised people who eat oysters and other shellfish to eat them fully cooked.

The findings appeared in the journal Applied and Environmental Microbiology.

Aug 28
Nutrition more important for healthy heart than checking calories, claims Indian scientist
Washington D.C: Researchers have suggested that shifting focus from calorie counting to nutritional value of foods is good for the heart and could curb the chances of obesity.

Aseem Malhotra, a scientist, and other doctors have asserted that simple dietary changes could rapidly improve health outcomes at the population level.

Regular consumption of sugary drinks is associated with a significantly increased risk of type 2 diabetes whereas regular consumption of a handful of nuts (30 g of walnuts, 15 g of almonds and 15 g hazelnuts) or four tablespoons of extra virgin olive oil (around 500 calories) is associated with a significantly reduced risk of heart attack and stroke.

According to the Action for Health in Diabetes trial, low calorie diet on top of increased physical activity in patients with type 2 diabetes was not associated with a reduced risk of cardiovascular death despite significant weight loss and a monitoring period of 13.5 years.

Researchers insisted that shifting the focus away from calories and emphasizing a dietary pattern that focuses on food quality rather than quantity would help to rapidly reduce obesity and cardiovascular risk besides other related diseases.

They stated evidence has shown that poor diet was consistently responsible for more disease and death than physical inactivity, smoking and alcohol put together, and concluded that it was time to stop counting calories and time to instead promote good nutrition and dietary changes that could rapidly and substantially reduce cardiovascular mortality.

The study is published in the Journal Open Heart.

Aug 25
Some people are truly happier single, study says
Generally speaking, sociologists find that people in relationships tend to be happier and more satisfied than single people. But a new study makes clear that for some, being single is the way to be.

It all depends on how individuals deal with conflict in relationships-those who hate it and try to avoid it at all costs report being just as happy when they're single as people in committed relationships, the New Zealand researchers write at EurekaAlert.

In researcher-speak, such people have high "avoidance social goals," and when they're in relationships, they often end up being miserable. "It's a well-documented finding that single people tend to be less happy compared to those in a relationship, but that may not be true for everyone," says lead researcher Yuthika Girme of the University of Auckland.

Her survey involved more than 4,000 people age 18 to 94. The results show that "you can never say one size fits all," a George Mason professor not involved with the study tells HealthDay.

But before singles start exulting in I-told-you-sos, he adds that people who can't deal with conflict tend to be a little neurotic and might benefit from counseling.

Such studies are important as the number of single people rises, notes Discovery, which says 51% of adult Americans fall in the bucket. It cites previous research showing that people who have a strong fear of being alone often end up in lousy relationships, too.

"Taken together, these studies suggest that not everyone is cut out for relationships," writes Talal al-Khatib. "The single life isn't so bad after all." (Another study finds that for those with depression, having happy friends helps.)

Aug 24
Instant oatmeal breakfast curbs appetite at lunch
Having a hearty portion of instant oatmeal for breakfast enhances satiety and feelings of fullness, thereby helping you eat less at lunch, new research has found.

A bowl of instant oatmeal helps curb food intake at lunch better than a leading oat-based, cold cereal -- even when each bowl provided the same number of calories, the findings showed.

The researchers found that a 250-calorie instant oatmeal serving (with an additional 113 calories of skim milk) enhanced satiety and feelings of fullness, reduced the desire to eat and led to lower caloric intake at lunch, compared to a 250-calorie serving of cold, oat-based cereal, also served with an additional 113 calories of skim milk.

"The satiety benefits of instant oatmeal alone were important findings," said lead author Candida Rebello from Louisiana State University in the US.

"When we took it a step further and evaluated the intake four hours post-breakfast, we found that after consuming instant oatmeal, the participants chose to eat significantly less at lunch compared to those who ate the oat-based, cold cereal," Rebello noted.

After an analysis of the types of fibre in each cereal, the researchers suspected that the higher level of the polysaccharides beta-glucan in the instant oatmeal contributed to its satiating effect over the oat-based, cold cereal.

The processing of the cold cereal might lead to changes in the oat fibre that reduced its ability to enhance satiety, the researchers noted.

Researchers presented the participants with a lunch meal of their choice - turkey, ham, roast beef or vegetable patty sandwiches and a calorie-free or calorie-containing beverage, alongside potato crisps and cookies.

The lunches offered ranged from 2,600 to 2,800 calories and participants were told to "eat to satisfaction".

The researchers found that total calorie intake was significantly lower following consumption of instant oatmeal compared to the cold cereal, as were fat and protein intake.

The findings were reported in the Journal of the American College of Nutrition.

Browse Archive