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Feb 06
Red wine, peanuts may help prevent age-related memory loss
A new study has recently revealed that compound found in grapes, red wine and peanuts may help prevent age-related memory loss.

Ashok K Shetty, Ph.D., a professor in the Department of Molecular and Cellular Medicine and Director of Neurosciences at the Institute for Regenerative Medicine, has been studying the potential benefit of resveratrol, an antioxidant that is found in the skin of red grapes, as well as in red wine, peanuts and some berries.

Resveratrol has been widely touted for its potential to prevent heart disease, but Shetty and a team that includes other researchers from the health science center believe it also has positive effects on the hippocampus, an area of the brain that was critical to functions such as memory, learning and mood.

Resveratrol might even be able to help people afflicted with severe neurodegenerative conditions such as Alzheimer's disease.

The study is published in the Scientific Reports.

Feb 05
Whole grains, polyunsaturated fats help keep lung diseases at bay
If you want to keep your lungs healthy and disease free, consume diet rich in whole grains, polyunsaturated fats and nuts, and low in red and processed meat, refined grains and sugary drinks, claims a study.

Eating a diet rich is associated with a lower risk of chronic lung disease (chronic obstructive pulmonary disease or COPD), such as emphysema and bronchitis, which block the airways and restrict oxygen flow around the body. It is currently ranked the third leading cause of death worldwide.

A team of researchers based in France and the USA, set out to investigate the association between the Alternate Healthy Eating Index 2010 (AHEI-2010) - a measure of diet quality based on current scientific knowledge - and the risk of COPD.

They analyzed data for more than 120,000 US men and women taking part in the Nurses' Health Study from 1984 to 2000 and the Health Professionals Follow-up Study from 1986 to 1998.

The AHEI-2010 diet score is based on 11 components, with a higher score reflecting high intakes of vegetables, whole grains, polyunsaturated fats, nuts, and long chain omega-3 fats - moderate intake of alcohol - and low intakes of red and processed meats, refined grains, and sugar sweetened drinks.

Over the study period, 723 cases of newly diagnosed COPD occurred in women and 167 in men.

After adjusting for 12 factors such as age, physical activity, body mass index, smoking and ethnicity, the risk of newly diagnosed COPD was one third lower in participants who ate the healthiest AHEI-2010 diet compared with those who ate the least healthy diet. The findings were similar in ex-smokers and current smokers - and in both women and men.

By contrast, the AHEI-2010 diet score was completely unrelated to incident asthma.

Authors said that, it was a novel finding that supports the importance of diet in the pathogenesis of COPD. Although efforts to prevent COPD should continue to focus on smoking cessation, these prospective findings support the importance of a healthy diet in multi-interventional programs to prevent COPD.

The study is published in The BMJ.

Feb 04
Slimy snail facials latest beauty regimen for perfect skin
Snail facial has come out to be the latest beauty craze among the ladies across Thailand, it has been revealed.

Two Frenchmen opened the first such spa in Chiang Mai, Thailand, with just 100 of the garden creatures initially but now they have upgraded it with 30,000 snails on their organic farm, the Daily Express reported.

In this treatment around 30,000 snails are being used that helps to get a youthful glow and heals all the burns, acne, stretch marks, scars and wrinkles.

Luc Champeyroux, a co-founder said that they take care of the snails as their own family or babies, and always keep them in good condition.

This slimy skin regime could be under threat as public health inspectors descended on the Thai spa to investigate whether the treatment was safe or are they harmful, but the results are yet to be disclosed.

Feb 03
Ebola vaccine trial on volunteers begins in Liberia
The actual trial of Ebola vaccine has begun in the Liberian capital Monday on the first batch of volunteers.

The vaccination trial, which started following a launch event featuring musicians, is a product of a partnership set up by the governments of Liberia and United States.

Guests clapped, danced along and nodded as musicians sang lyrics that explain the purpose and intent of the Ebola vaccination trial.

Liberians have not shown much excitement about the vaccines amid conspiracy theories.

Liberian Vice President Joseph Nyumah Boakai launched the vaccines in the presence of top US Embassy and World Health Organization officials on Sunday.

The vaccines are "very important for Liberia and for the world," Boakai was quoted as saying to AP.

Boakai urged Liberians "to take courage because it is going to work."

The vaccines contain a bit of Ebola virus that helps trigger an immune response against the virus, according to a document from PREVAIL, the acronym for Partnership for Research on Ebola Vaccines in Liberia, as the US-Liberia collaboration is called.

According to the BBC, scientists aim to vaccinate around 30,000 volunteers and health care workers in the country starting Monday.

The Ebola outbreak in West Africa has killed nearly 9,000 people with 3,600 succumbing to the disease in Liberia alone since it was identified in March.

Feb 02
Key to preventing blindness and stroke devastation discovered
A team of scientists has discovered key to preventing blindness and stroke devastation.

Researchers at LSU Health New Orleans discovered gene interactions that determine whether cells live or die in such conditions as age-related macular degeneration and ischemic stroke. These common molecular mechanisms in vision and brain integrity can prevent blindness and also promote recovery from a stroke.

Researcher Nicolas Bazan said that studying the eye and the brain might hold the key to creating therapeutic solutions for blindness, stroke and other seemingly unrelated conditions associated with the central nervous system. The eye is a window to the brain.

Bazan added that during the last few years, his laboratory has been immersed in studying gene regulation and they have uncovered a novel control that makes definitive decisions about whether a retina or brain cell will survive or die when threatened with disease onset. The gene mechanism that they discovered is the interplay of two genes turned on by the messenger Neuroprotectin D1 (NPD1), which is made from the essential fatty acid, docosahexaenoic acid (DHA).

The research team worked with human RPE cells and an experimental model of ischemic stroke and discovered novel mechanisms in cells with the ability to activate pathways that crosstalk one to another and then assemble consolidated responses that decide cell fate.

The researchers found that the powerful messenger, NPD1, is produced on-demand in the brain and retina and that it elicits a network of positive signals essential for the well-being of vision and cognition.

They showed that NDP1 bioactivity governs key gene interactions decisive in cell survival when threatened by disease or injury and demonstrated that not only does NPD1 protect photoreceptors, but it also promotes remarkable neurological recovery from the most frequent form of stroke in humans.

The paper is published online in Cell Death and Differentiation, a Nature journal.

Jan 31
Better diet and nutrition critical in maintaining mental health
Scientists claim that a good diet and proper nutrition is essential in maintaining mental health.

A new international study led by the University of Melbourne and Deakin University has stated that as with a range of medical conditions, psychiatry and public health should now recognise and embrace diet and nutrition as key determinants of mental health.

Lead author, Dr Jerome Sarris said that while the determinants of mental health were complex, the emerging and compelling evidence for nutrition as a key factor in the high prevalence and incidence of mental disorders suggested that nutrition was as important to psychiatry as it is to cardiology, endocrinology and gastroenterology.

In the last few years, significant links have been established between nutritional quality and mental health. Scientifically rigorous studies have made important contributions to our understanding of the role of nutrition in mental health, he added.

Findings of the review revealed that in addition to dietary improvement, evidence now supports the contention that nutrient-based prescription has the potential to assist in the management of mental disorders at the individual and population level.

Studies show that many of these nutrients have a clear link to brain health, including omega-3s, B vitamins (particularly folate and B12), choline, iron, zinc, magnesium, S-adenosyl methionine (SAMe), vitamin D, and amino acids.

"While we advocate for these to be consumed in the diet where possible, additional select prescription of these as nutraceuticals (nutrient supplements) may also be justified," Dr Sarris said.

It was time for clinicians to consider diet and additional nutrients as part of the treating package to manage the enormous burden of mental ill health, he said.

The study is published in The Lancet Psychiatry today.

Jan 30
How green tea rids you of oral cancer
Green tea consists of an ingredient , which may help kill oral cancer cells, without touching the healthy cells, says a new research.

Associate professor Joshua Lambert at Penn State said that earlier studies had shown that epigallocatechin-3-gallate-EGCG-a compound found in green tea, killed oral cancer cells without harming normal cells, but researchers did not understand the reasons for its ability to target the cancer cells. The current study shows that EGCG may trigger a process in the mitochondria that leads to cell death.

The researchers studied normal human oral cells side-by-side with human oral cancer cells to determine how EGCG was affecting cancer cells differently than normal cells.

They grew the normal and cancer cells on petri dishes and then exposed them to EGCG, the major polyphenol found in green tea, at concentrations typically found in the saliva after chewing green-tea chewing gum. At various times, the researchers would collect the cells and check for oxidative stress and signs of antioxidant response.

The researchers said that a protein called sirtuin 3 -- SIRT3 -- was critical to the process, so the idea that EGCG might selectively affect the activity of sirtuin 3 in cancer cells-to turn it off-and in normal cells-to turn it on-was probably applicable in multiple kinds of cancers, Lambert said.

The study builds on earlier research on how EGCG affected oral cancer, a disease that is expected to kill more than 8,000 people in the United States this year.

He said the next step would be to study the mechanism in animals. If those tests and human trials are successful, the researchers then hope to create anti-cancer treatments that are as effective as current treatments without the harmful side effects.

Lambert said chemotherapy drugs just targeted rapidly dividing cells, so cancer divides rapidly, but so did the cells in your hair follicles and cells in your intestines, leading to a lot of side effects. But green tea consumption didn't have such side effects.

The study is published in the online issue of Molecular Nutrition and Food Research.

Jan 29
Beetroot juice boosts exercise function in heart patients
A small yet significant study shows that beetroot juice improves exercise function in chronic obstructive pulmonary disease (COPD) patients.

The new research by Wake Forest University looked at a small group of COPD patients who drank beetroot juice as compared to a placebo drink before exercise.

"The intent of this study was to determine if acute ingestion of beetroot juice, which is rich with nitrates, prior to exercising could improve the exercise capacity of COPD patients," said Michael Berry, chair of Wake Forest's department of health and exercise science.

COPD makes it difficult for patients to breathe and worsens over time.

In turn, they tend to limit their activities, become more sedentary, and lose fitness and physical function.

The findings showed overall that those patients who drank beetroot juice were able to extend their exercise time and had reduced exercise diastolic and resting systolic blood pressures.

"This is the first study to demonstrate beneficial effects of dietary nitrite supplementation on exercise performance and blood pressure in patients with COPD," he added. One of the benefits of exercise is that if you get positive results, you are more likely to continue doing it.

"If beetroot juice positively impacts those results, it could motivate COPD patients to continue to be physically active and improve their health," he added.

The research appeared in the journal Nitric Oxide: Biology and Chemistry.

Jan 28
Flexible work schedules of employees improve health, sleep
A new study has examined that people who have flexible work schedules have better health and they sleep properly than their counterparts.

Orfeu M. Buxton, associate professor of biobehavioral health, Penn State, said that in the absence of sufficient sleep, they are not as attentive or alert, they process information more slowly, miss or misinterpret social and emotional cues and decision making is impaired.

The researchers followed 474 employees as part of a Work, Family and Health Network study conducted at an information technology company, with about half of the employees serving as the control while the other half experienced the study intervention. Both employees and their supervisors participated.

The intervention was designed to reduce conflicts between work and personal life, and focused on two main cultural shifts: allowing employees to decide on when and where they worked and training supervisors to support their employees' personal lives. Those who were assigned to the intervention were encouraged to be completely flexible about when and where they would work at the office, from home or elsewhere while still working the same number of hours as the control group. All of the participants wore a sleep-monitoring watch, a device that tracks movement to monitor periods of sleep.

At 12 months, the researchers found that employees who participated in the intervention experienced an average of eight minutes more sleep per night, which is nearly an hour more sleep per week, than the control group. Intervention participants' perceptions of their sleep sufficiency also improved.

Buxton added that work can be a calling and inspirational, as well as a paycheck, but work should not be detrimental to healthIt is possible to mitigate some of the deleterious effects of work by reducing work-family conflict and improving sleep.

Jan 27
Chewing gum enhances oral health
Chewing gum can enhance oral health by removing 100 million bacteria from your mouth in just 10 minutes, suggests a new study.

Researchers at the University of Groningen in the Netherlands found that chewing gum can trap and remove bacteria from the oral cavity.

In the study, five biomedical engineering students were recruited to chew two different standard types of spearmint gum for various lengths of time ranging from 30 seconds to 10 minutes.

Afterwards, the gum was spit into a cup filled with sterile water to be analysed, 'Medical Daily' reported.

There were were about 100 million bacteria detected on each piece of chewed up gum, with the number increasing as chewing time increased.

However, after 30 seconds of chewing, the gum starts to lose its adhesiveness, meaning it traps fewer bacteria overall.

"Trapped bacteria were clearly visualised in chewed gum using scanning-electron-microscopy," researchers said in the paper published in the journal PLOS ONE.

Previous research has shown that using a new, clean toothbrush without any toothpaste can remove around 100 million colony-forming units (CFUs) per brush, which would put chewing of gum on par with the mechanical action of a toothbrush.

"Chewing gum however, does not necessarily remove bacteria from the same sites of the dentition as does brushing or flossing, therefore its results may be noticeable on a more long-term than those of brushing or flossing," researchers said.

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