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May 10
Cooking meat with beer may protect you from cancer
Beer, when used as a marinade, can help reduce the formation of potentially harmful cancer-causing substances in grilled meats, scientists have found.

Previous studies have shown an association between consumption of grilled meats and a high incidence of colorectal cancer.

Polycyclic aromatic hydrocarbons (PAHs) are substances that can form when meats are cooked at very high temperatures, like on a backyard grill.

High levels of PAHs, which are also in cigarette smoke and car exhaust, are associated with cancers in laboratory animals, although it is uncertain if that is true for people.

Beer, wine or tea marinades can reduce the levels of some potential carcinogens in cooked meat, but little was known about how different beer marinades affect PAH levels, until now.

The researchers, from the University of Vigo in Spain and University of Porto in Portugal, grilled samples of pork marinated for four hours in Pilsner beer, non-alcoholic Pilsner beer or a black beer ale, to well-done on a charcoal grill.

Black beer had the strongest effect, reducing the levels of eight major PAHs by more than half compared with unmarinated pork.

"Thus, the intake of beer marinated meat can be a suitable mitigation strategy," researchers said.

The study appears in American Chemical Society's Journal of Agricultural and Food Chemistry.

May 10
Being forty never too late to start endurance training: Study
A new study suggests that 40 is not too old to start endurance training.

The study of healthy senior men has found that "relatively intensive" endurance exercise confers benefits on the heart irrespective of the age at which they began training.

The benefits were evident and comparable in those who had started training before the age of 30 or after the age of 40. As a result, the investigators said.

The study, which was performed in France, was reported at the EuroPRevent congress 2014 in Amsterdam by David Matelot, from the Inserm 1099 unit in Rennes, France.

The study was performed in 40 healthy men (without cardiovascular risk factors) aged between 55 and 70 years who were divided for assessment according to the level of exercise they took and the ages at which they began. 10 of the men had never exercised for more than 2 hours a week throughout their lives, and 30 had exercised for at least 7 hours a week for over five years, either beginning their programmes before the age of 30 or after the age of 40.

The regular exercise they took was either running or cycling.

"Despite biological changes with age, the heart still seems - even at the age of 40 - amenable to modification by endurance training. Starting at the age of 40 does not seem to impair the cardiac benefits," Matelot said.

"However, endurance training is also beneficial for bone density, for muscle mass, for oxidative stress. And these benefits are known to be greater if training was started early in life," he added.

May 09
Now, implantable device that could keep high blood pressure at bay
Researchers in Germany have created an implantable device that reduces blood pressure by sending electrical signals to the brain.

The device has successfully reduced the blood pressure in rats by 40 percent without any major side effects, and could offer hope for a significant proportion of patients worldwide who do not respond to existing medical treatment for the condition.

The device consists of 24 individual electrodes that are integrated into a micro-machined cuff. It is designed to wrap around the vagal nerve, which extends from the brainstem to the thorax and abdomen, supplying and stimulating various major organs including the heart and major blood vessels.

The device works by picking up signals from specific sensors, known as baroreceptors, which are activated when blood vessels stretch. Some baroreceptors are grouped together in concentrated areas in the aortic arch and report their information to the brainstem via fibres in the vagal nerve. These baroreceptors function to control short-term fluctuations in blood pressure.

The device has been designed to identify only those fibres that influence the blood pressure and avoid those that are responsible for heart rate, the power of heart beat, ventilation and other vital functions.

The results have been published in IOP Publishing's Journal of Neural Engineering.

May 09
Women over 40 most affected by osteoarthritis
Women over the age of 40 are most affected by osteoarthritis and this is corroborated by the fact that they form 60 percent of the patients that undergo total knee replacement, an expert said Thursday.

However, despite this, it has been observed that women delay surgery due to various factors which leaves them with agony and incapacitation, he said.

"Osteoarthritis of the knee is the most common cause of disability. And it is a disease of age that affects more women than men on a 60-40 basis," said Arthritis Foundation of India (AFI) chairman Sushil Sharma.

"General physicians sometimes have advised patients to wait as long as they can before pursuing knee replacements, with the thinking that it is an once-in-a-lifetime surgery that should last an average of 15 to 20 years.

"However, delaying surgery beyond a point can limit the quality of life of patients because how they function before surgery have bearing on their performance afterward," he said.

The Arthritis Foundation of India appealed against the general lack of awareness and negligence towards the healthcare of patients with osteoarthritis.

Today with the advancement in technology there are knees made of newer material like oxidized zirconium that last longer with the replacement lasting for up to 30 years, it said in a release.

May 07
Rwanda plans to eliminate malaria deaths by 2018
The Rwandan government Tuesday launched a $329 million plan to stop malaria deaths in the country by 2018.

The Rwanda Malaria Strategic Plan is a public health campaign to be coordinated by the Rwanda Biomedical Centre geared at eradicating the disease that claimed the lives of more than 400 people last year, according to Xinhua.

The campaign launched in Kigali focuses on encouraging all Rwandans to sleep under an insecticide-treated mosquito net, rapid testing and treatment by community health workers within 24 hours of a patient showing signs of malaria and close monitoring of the disease by health personnel.

Speaking at the launch, Corine Karema, director of the malaria division at the Rwanda Biomedical Centre, insisted that mosquito nets remain the best way to prevent malaria infection.

"With massive distribution of mosquito nets we notice a 50 percent reduction in infections," Karema told reporters.

She explained that free mosquito nets are given to children under five when they visit a health centre for their measles vaccination and to expectant mothers during prenatal checks.

Meanwhile, Sylvia Muteteli, who works on malaria community outreach with Urunana Development Communication said some people shun sleeping under mosquito nets for various reasons ranging from allergies claims to inconvenience to use.

Muteteli said her organisation, which played a role in developing the strategic plan, tries to discourage the reluctance through radio plays to raise awareness on the importance of sleeping under a mosquito net.

She, however, appealed to local leaders to get more involved in the malaria prevention effort.

There will be a concerted effort to have more community leaders involved in awareness on malaria prevention and treatment, according to Karema.

In 2011 only 210,000 malaria cases were reported in Rwanda. This led people to believe malaria was no longer a threat, Alphonse Rukundo, an epidemiologist specialising in malaria said at the launch.

The Rwanda Malaria Strategic Plan will be funded by the government of Rwanda and the US president's Malaria Initiative and Global Fund.

May 07
Poor care causes needless asthma deaths: Report
Many asthma sufferers are dying needlessly because of poor medical care and complacency among doctors and patients, according to a report published Tuesday by British medical experts.

Researchers from the Royal College of Physicians examined 195 asthma deaths, including 28 children, and found at least one major preventable factor in around 70 percent of cases, Xinhua reported.

Asthma sufferers were not managing their disease well because of complacency or lack of knowledge, and medical staff did not recognise life-threatening danger signs, according to the report.

During the final attack of asthma, 45 percent of the 195 people were known to have died without seeking medical assistance or before emergency medical care could be provided. Fifty-seven percent of them were not recorded as being under specialist supervision during the 12 months prior to death.

The experts also found evidence of excessive prescribing of reliever medication, and evidence of inappropriate prescribing of bronchodilator inhalers.

The report called for an end to "complacency" around asthma care, and recommended that better monitoring and improved education for doctors, nurses, patients and carers should be implemented in future.

May 06
Gardening offers much needed health benefits to younger adults
Researchers have said that gardening can not only enhance home and community landscapes and provide low-cost food sources, the level of physical activity required also offers a multitude of health benefits to young adults.

Studies have confirmed that engaging in gardening can lower cholesterol and blood pressure, and increase psychological well-being.

Researchers from Konkuk University and Hongik University in Seoul, South Korea, published a study in HortTechnology that evaluated the intensity of gardening activities for adults in their 20s.

Study's lead author Ki-Cheol Son said that the exercise intensity of physical activity may differ between age groups and fitness levels, and there was not enough data on the metabolic equivalents of gardening tasks in different age groups to develop a garden exercise program for maintaining or improving health conditions.

Fifteen university students in their 20s participated in the study in South Korea. Each subject performed 10 common gardening tasks in a high tunnel and in a nearby grassy area with a vegetable garden and weeds.

The subjects visited the garden plot twice and performed five gardening tasks during each visit; each task lasted for 5 minutes and was followed by a 5-minute rest. Subject wore a portable telemetric calorimeter and respired into the facemask during the gardening tasks and resting periods so researchers could measure their oxygen uptake.

The subjects also wore a heart rate monitor to record heart rate data during the gardening tasks and resting periods via radiotelemetry.

The research team evaluated the data and determined that all 10 gardening tasks were "moderate- to high-intensity" physical activities for the research subjects. Planting transplants, mixing growing medium, watering, harvesting, sowing, hoeing, mulching, raking, and weeding were all classified as "moderate intensity", while digging was a found to be a "high-intensity" activity and was the most intense task in study.

May 06
Smiling can help fight memory loss
A new study has revealed that humor and laughter can help lessen the damage that stress hormone cortisol has on memory and learning ability in the elderly.

According to the researchers at Loma Linda University, there was a significant decrease in cortisol concentrations among both groups who watched a funny video and showed greater improvement in all areas of the memory assessment when compared to controls.

Gurinder Singh Bains said that their findings offer potential clinical and rehabilitative benefits that can be applied to wellness programs for the elderlyand the cognitive components, such as learning ability and delayed recall, become more challenging as people age and are essential to older adults for an improved quality of life.

The researchers said that the less stress one has the better their memory, as humor reduces detrimental stress hormones like cortisol that decrease memory hippocampal neurons, lowers the blood pressure, and increases blood flow and mood state.

The study revealed that the act of laughter-or simply enjoying some humor-increases the release of endorphins and dopamine in the brain, which provides a sense of pleasure and reward and the positive and beneficial neurochemical changes, in turn, make the immune system function better.

May 05
Smoking during pregnancy may raise heart defects risk in babies
Researchers have shown that risk for congenital anomalies is highest among babies born to older women who smoke.

The authors of this study used birth certificate data and hospital discharge records from Washington state to determine if maternal smoking during the first trimester of pregnancy is linked to heart defects and if so, what types of defects.

Lead author Patrick M. Sullivan, MD, FAAP, clinical fellow in pediatric cardiology at Seattle Children's Hospital and a master's student in epidemiology at the University of Washington School of Public Health, said I care for kids with complex congenital heart disease on a daily basis, and I see these kids and their families enduring long hospitalizations and often sustaining serious long-term complications as a result of their disease.

Sullivan said usually, the cause of a heart defect is unknown. I saw this research as an opportunity to study what might be a preventable cause of congenital heart defects.

Using hospital discharge records, researchers identified 14,128 children born with a variety of heart defects from 1989-2011. They matched these cases to 62,274 children without heart defects born in the same year.

Then, they compared the proportion of children with heart defects whose mothers reported smoking during pregnancy to the proportion of children without heart defects whose mothers smoked. Mothers' smoking status, as well as how much they smoked daily, was available from birth certificates.

Newborns whose mothers smoked were at about a 50 to 70 percent greater risk for anomalies of the valve and vessels that carry blood to the lungs (pulmonary valve and pulmonary arteries) and about a 20 percent greater risk for holes in the wall separating the two collecting chambers of the heart (atrial septal defects). All of these defects often require invasive procedures to correct.

May 05
Environmental factors as important as genes in understanding autism
Researchers have said that environmental factors are more important than previously believed in understanding the causes of autism, and equally as important as genes.

The study also shows that children with a brother or sister with autism are 10 times more likely to develop autism; 3 times if they have a half-brother or sister; and 2 if they have a cousin with autism, providing much needed information for parents and clinicians for assessing individual risk.

The study led by researchers at King's College London, Karolinska Institutet in Sweden and Mount Sinai in the US, looked at over 2 million people.

Using Swedish national health registers, the researchers analysed anonymous data from all 2 million children born in Sweden in between 1982 and 2006, 14,516 of which had a diagnosis of ASD. The researchers analysed pairs of family members: identical and non-identical twins, siblings, maternal and paternal half-siblings and cousins.

The study involved two separate measures of autism risk - heritability, which is the proportion of risk in the population that can be attributed to genetic factors; and Relative Recurrent Risk which measures individual risk for people who have a relative with autism.

Environmental factors are split into 'shared environments' which are shared between family members (such as family socio-economic status), and 'non-shared environments' which are unique to the individual (such as birth complications or maternal infections or medication during the pre and perinatal period). In this study, factors which are unique to the individual, or 'non-shared environments' were the major source of environmental risk.

In the other part of the study, the researchers looked at individual risk. In the general population, autism affects approximately 1 in 100 children. The researchers found that children with a brother or sister with autism were 10.3 times more likely to develop autism; 3.3-2.9 times if they had a half-brother or sister with autism; and 2.0 times if they had a cousin with autism.

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