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Apr 14
Confirmed: Smoking ruins your taste buds
Well there are umpteen number of reasons why you shouldn't smoke. Adding to that, there is another one now which says that smoking totally ruins your taste buds. Your taste buds being affected, you won't be able to completely enjoy the food/drinks that you really like.

It happens so that smokers' ability to taste is impaired by toxic chemicals found in tobacco, even after they have quit smoking. So they do not enjoy their coffee despite the strong, bitter taste of caffeine which can be easily detected.

Scientists tested how well 451 volunteers could recognise the four basic flavours of sweet, sour, bitter and salty, as well as the intensity of each taste as a part of this study.

Researchers found that whether the volunteers smoked or not did not affect whether they could recognise salty, sweet or sour tastes -- but it did have an effect where the bitter taste of caffeine was concerned.

One in five smokers and one in four ex-smokers could not correctly recognise the taste.However, 13 percent of non-smokers also failed the taste test.

According to the researchers ,the build-up of tobacco in the body could stop taste buds renewing themselves and so harm a person's ability to recognise certain tastes, even after they have stopped smoking.

Apr 14
189,000 kids get anti-polio vaccine in Syria
A total of 189,000 children, aged below five, have been vaccinated against polio for the past week in the the central province of Homs, as part of a national government campaign in the war-torn country, state media reported.

The national vaccination campaign, the fifth one since last year, started Sunday. It has provided children under the age of five with free vaccines in 50 towns of Homs and some of its hotspot suburbs, Xinhua quoted citing data from the health department of Homs.

The World Health Organisation (WHO) said recently that the recent polio outbreak in Syria is the first since 1999.

Preliminary evidence indicates that the poliovirus is of Pakistani origin and is similar to the strain detected in Egypt, the West Bank and Gaza Strip over the last 12 months.

Polio is a highly infectious disease caused by a virus that invades the nervous system. It can cause complete paralysis in a matter of hours. The virus enters the body through the mouth and multiplies in the intestine.

According to WHO, the health situation in Syria has been deteriorating due to shortage of medicines and medical workers, destruction of health facilities and difficult access to health care.

Apr 11
Consuming high-fat diet increases breast cancer risk
A new study has revealed that consuming a high-fat diet is associated with increased risk of certain types of breast cancer.

According to the researchers, high total and saturated fat intake were associated with greater risk of estrogen receptor- and progesterone receptor-positive (ER+PR+) breast cancer (BC), and human epidermal growth factor 2 receptor-negative (HER2-) disease.

Published data from epidemiological and case-control studies on the association between high fat intake and BC risk have been conflicting, which may be attributable to difficulties obtaining accurate information on fat intake and because of limited heterogeneity of intake within a specific geographic area from which the study cohorts live.

Furthermore, BC is now classified clinically into subtypes by ER, PR, and HER2 expression status and each subtype has its own prognosis and set of risk factors, which may also contribute to the inconsistencies in the published reports on this relationship.

Sabina Sieri, Ph.D., from the Epidemiology and Prevention Unit of the Department of Preventive and Predictive Medicine at Fondazione IRCCS Istituto Nazionale Dei Tumori in Milan Italy, and colleagues prospectively analyzed data from 10,062 BC patients from the EPIC study with 11.5 years of follow-up.

The authors report high total and saturated fat intake were associated with greater risk of ER+PR+ BC. High saturated fat intake was also associated with greater risk of HER2- disease.

The authors conclude, "a high-fat diet increases BC risk and, most conspicuously, that high saturated fat intake increases risk of receptor-positive disease, suggesting saturated fat involvement in the etiology of receptor-positive BC."

The study is published in the Journal of the National Cancer Institute.

Apr 11
Merck's hepatitis C drugs show 98% cure rate in trial
Offering new hopes to millions of people infected with Hepatitis C, a two-drug combination by Merck & Co to treat the infectious liver disease has showed a cure rate of 98% in a mid-stage trial.

The results of the 12-week study called C-Worthy were presented on Thursday at the annual meeting of the European Association for the Study of the Liver (EASL) in London.

In the study, 44 patients were treated with MK-5172 and MK-8742 once a day for 12 weeks, where 43 of them achieved sustained virologic response (SVR), which is considered cured or a 98% cure.

Merck also said that when the two drugs were given to some patients along with ribavirin, an older virus-fighting drug, it showed a 94% cure rate.

Gilead Sciences Inc, AbbVie and Bristol-Myers Squibb Co are also developing a new generation of all-oral hepatitis C treatments that in previous trials have demonstrated cure rates in excess of 90%.

The drug maker said after analysing the results of the study, it has begun to initiate a phase 3 trial.

Apr 08
New drug may help prevent advanced breast cancer from progressing
It could be a groundbreaking treatment option for women with Breast cancer.Scientists have revealed that a new drug can help prevent advanced breast cancer from progressing.

The drug, palbociclib could cut in half the risk that the cancer would worsen.

The principal investigator Dr. Richard S. Finn, remarked that the magnitude of benefit they are seeing is not something commonly seen in cancer medicine studies.

The drug, palbociclib, developed by pharmaceutical giant, Pfizer, appears to prolong survival, though not by a statistically significant amount.

Finn added that a statistically significant survival benefit should not have been expected at this point because only 61 of the 165 patients in the trial had died.

Apr 08
Drink green tea to boost your brain power
Researchers have reporting first evidence that green tea extract enhances the cognitive functions, in particular the working memory.

In the new study, the researcher teams of Prof. Christoph Beglinger from the University Hospital of Basel and Prof. Stefan Borgwardt from the Psychiatric University Clinics found that green tea extract increases the brain's effective connectivity, meaning the causal influence that one brain area exerts over another.

This effect on connectivity also led to improvement in actual cognitive performance: Subjects tested significantly better for working memory tasks after the admission of green tea extract.

For the study healthy male volunteers received a soft drink containing several grams of green tea extract before they solved working memory tasks. The scientists then analyzed how this affected the brain activity of the men using magnetic resonance imaging (MRI).

The MRI showed increased connectivity between the parietal and the frontal cortex of the brain. These neuronal findings correlated positively with improvement in task performance of the participants. "Our findings suggest that green tea might increase the short-term synaptic plasticity of the brain," says Borgwardt.

The study has been published in the journal Psychopharmacology.

Apr 07
E-cigarettes next big smoking poison, warns study
The fast spreading e-cigarettes are undoing the anti-smoking efforts of the last three decades, health experts warn.

Also, the number of people being poisoned by e-cigarettes in the US has gone up manifold in the last few years, according to official reports.

The number of calls to poison centres in the US relating to e-cigarettes has risen from one per month in September 2010 to 215 per month in February 2014.

The figures, from the Centres for Disease Control and Prevention (CDC), also show the number of calls per month relating to conventional cigarettes did not increase in the same way.

The CDC statistics show that more than half of the calls relate to children under the age of five.

Poisoning related to e-cigarettes involves the liquid containing nicotine used in the devices.

"This report raises another red flag about e-cigarettes -- the liquid nicotine used in e-cigarettes can be hazardous," CDC director Tom Frieden said in a statement.

E-cigarette liquids come in candy and fruit flavours that are appealing to children.

"The most recent National Youth Tobacco Survey showed e-cigarette use is growing fast, and now this report shows e-cigarette related poisonings are also increasing rapidly," Tim McAfee, director of CDC's office on smoking and health, was quoted as saying.

The study comes close on the heels of news that the Welsh government might include e-cigarettes under the smoking ban.

Apr 07
The weed that causes cancer may well kill it
Tobacco has been associated with and much maligned for causing cancers. Researchers have now found that the tobacco plant's defence mechanism could well work in humans to destroy invading cancer cells.

A molecule called NaD1 is found in the flower of the tobacco plant that fights off fungi and bacteria.

This compound also has the ability to identify and destroy cancer, the team discovered.

"This is a welcome discovery whatever the origin," Mark Hulett from La Trobe Institute for Molecular Science in Melbourne was quoted as saying.

The molecule, found in nicotiana sylvestris (flowering tobacco) plant, forms a pincer-like structure that grips onto lipids present in the membrane of cancer cells.

It then effectively rips them open, causing the cell to expel its contents and explode.

According to researchers, this universal defence process could also potentially be harnessed for the development of antibiotic treatment for microbial infections.

The pre-clinical work is being conducted by the Melbourne biotechnology company Hexima.

"The preliminary trials have looked promising," said Hulett.

The study was published in the journal eLife.

Apr 05
'United effort needed against vector-borne diseases in South Asia'
Vector-borne diseases like dengue and malaria still have a significant impact on the socio-economic status of countries in south Asia, the WHO said Thursday, calling for a united effort against them.

"These diseases are still killing thousands of people in the WHO southeast Asia Region," a World Health Organization release said.

Forty percent of the global population at risk of malaria lives in the WHO southeast Asia region, home to a quarter of the world's population, it said.

"These are deadly but preventable diseases. The solution lies in a united and sustained effort from all of us," said WHO regional director Poonam Khetrapal Singh.

"This region recently defeated polio, it is time for us to show the same resolve to defeat malaria, dengue and other vector-borne diseases," she added.

Vector-borne diseases account for 17 percent of the estimated global burden of all infectious diseases with malaria being endemic in 10 of the 11 countries of the region, including India.

"With mass drug administration with effective coverage, there is no reason why diseases like lymphatic filariasis cannot be eliminated from the region," said Singh.

"Countries must prioritize vector-borne diseases in their national development agendas. Communities need to be empowered to fight this battle and protect themselves. Preventing and controlling vector-borne diseases is everyone's responsibility," she said.

Apr 05
Ebola claims more lives in Liberia
The deadly Ebola virus has claimed two more lives in Liberia, Minister of Health and Social Welfare Walter Gwenigale said Thursday, taking the death toll to seven in the West African nation.

Gwenigale told a regular press conference in Morovia, the country's capital city, that the two people included a woman who got infected as a result of taking care of her sister who contracted the virus in Lofa county. The woman died Wednesday night, Xinhua reported.

The minister told reporters that after contracting the virus, the woman travelled from Lofa to Chicken-soup Factory in Gardnersville and was later taken to Firestone by the taxi driver where she later died and that her child who is currently sick is being quarantined.

Gwenigale said the other one of the two newly deceased is a 25-year-old man who died at the Tapita Hospital in Nimba county few minutes after he was taken there for treatment.

He said though his death is not proven to be Ebola from standard laboratory test, the ministry concluded that he died of the deadly virus having considered the different signs and symptoms that go along with the virus and observed that they were exactly the same that affected him before he died.

He said Ebola is real and is present in Liberia and that no one Liberian should take it as a joking matter.

Ebola virus is considered one of the most aggressive virus known to date in part because of its rapidity to kill, which can be within one week from exposure or three to four days from the first symptoms become apparent. This leaves very little time for any treatment to act and save a sick individual.

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