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Jul 04
Being a vegan helps lose weight: Study
If you are looking for a size zero figure, then following a vegan diet that includes no animal products could offer better results than other weight-loss plans, says a study.

"Vegetarian diets are more effective than non-vegetarian diets for weight loss," said researcher Ru-Yi Huang of E-Da Hospital in Taiwan.

The study reviewed the results of twelve diet trials, involving 1,151 dieters who followed a specific eating regime for between nine and 74 weeks.

Overall, individuals assigned to the vegetarian diet groups lost significantly more weight (around 2.02 kg) than dieters who ate meat and other animal products.

Vegetarians who followed a vegan diet lost even more weight. Comparatively, they lost around 2.52 kg more than non-vegetarian dieters. Vegetarians who consumed dairy products and eggs lost around 1.48 kg more than those on a non-vegetarian diet.

According to Huang, the abundant intake of whole grains, fruits and vegetables might play a role in the favourable results seen in vegetarian diets.

Whole-grain products and vegetables generally have low glycaemic index values and do not cause blood sugar levels to spike. Fruits are rich in fiber, anti-oxidants, minerals and protective chemicals that naturally occur in plants.

Whole-grain products contain soluble fiber. Such so-called good fiber helps to delay the speed by which food leaves the stomach and ensures good digestion.

The researchers found that people following vegetarian diets that prescribe a lower than normal intake of calories (so-called energy restriction) also shed more kilograms than those without any such limitations being placed on their eating habits.

The findings appeared in the Journal of General Internal Medicine.

Jul 03
'Too much' available food to be blamed for obesity crisis
It's the abundance of food that's been causing an obesity epidemic, claims a new research.

Of the 56 out of 69 countries surveyed, average body weight had increased as a result of available food supply, with only countries hit by famine, natural disasters or civil war not in the list.

Researchers from the University of Auckland, New Zealand, and the National Institutes of Health in the US, said that it was major factor in the growing obesity epidemic throughout the world, the Telegraph reported.

In Britian, researchers found that each person had 3428 calories available to them each day, which was 70 per cent more than required by women, and 37 per cent more than men's recommended daily intake.

It has risen by 212 calories since 1993.

Lead author Stefanie Vandevijvere said their study showed that oversupply of available calories possibly leads to overconsumption of those calories, resulting in the weight gain seen in most countries.

Scientists also found that the increases were far in excess of what was required to explain the weight gain experienced by each country, suggesting that food waste had also increased substantially.

Weight gain has been stated as a risk factor for many major health problems, like diabetes, heart disease, stroke and even some cancers.

The study highlights the need for the governments to implement policies to make food healthier.

Dr Francesco Branca, director of the Department of Nutrition for Health and Development at WHO, countries need to look at how they guide the food system, and work across sectors including agriculture, the food production, distribution and retail industries, health, social welfare and education.

The study is published in the Bulletin of the World Health Organisation.

Jul 02
Eat nuts to keep obesity at bay
A new study has linked tree nuts to lower body weight and risk of obesity.

Researchers compared risk factors for heart disease and metabolic syndrome of tree nut consumers versus those who did not consume tree nuts. Tree nut (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) consumption was associated with lower body mass index, systolic blood pressure, insulin resistance and higher levels of high-density lipoprotein-cholesterol (good cholesterol).

In addition, tree nut consumers were 25 percent less likely to be obese and 21 percent less likely to have an elevated waist circumference than those who did not consume tree nuts.

Research has shown that nuts can help reduce the risk of cardiovascular disease and metabolic syndrome (MetS). The latter is a cluster of risk factors for cardiovascular disease and type 2 diabetes and includes elevated blood lipids, blood pressure, blood sugar, insulin resistance and abdominal obesity.

Maureen Ternus, Executive Director of the International Tree Nut Council Nutrition Research & Education Foundation (INC NREF), said that just 1.5 ounces of nuts per day (about 1/3 cup) can give you many of the important vitamins, minerals and energy you need throughout the day.

The study is published in Nutrition Journal.

Jun 30
Depressed? Go for red grapes and wine
A new study has found that red grapes and wine can help ease depression.

University of South Carolina School of Medicine's study found that resveratrol, a natural anti-inflammatory agent found in the skin of red grapes, can prevent inflammation as well as depression-related behaviors in rodents exposed to a social stress.

Susan K. Wood said that the research is very relevant to today's society because it investigates potential treatments for people with an increased susceptibility to depression and related disorders that arise due to social stress.

Wood added they hope their findings will encourage scientists who are running clinical trials to test the effectiveness of natural anti-inflammatory agents on depression, which is currently an understudied area.

Resveratrol appears to knock down inflammation throughout the body, said researcher Julie Finnell, adding that they found that administering resveratrol blocks the inflammation normally seen in animals undergoing the bullying stress and brings it to control levels.

In addition to being naturally present in the skin of red grapes and in red wine, resveratrol is also sold as supplement. Studies have shown that the natural agent might be responsible for red wine's ability to prevent blood vessel damage and reduce LDL cholesterol, and experiments using high doses of resveratrol in animals have suggested it might help protect from obesity and diabetes.

Jun 29
Beat post-race sniffles with tart cherry juice
A new study has suggested that tart cherry juice can reduce post-race respiratory tract symptoms after a marathon.

The study found that Montmorency tart cherry juice reduced upper respiratory tract symptoms associated with marathon running in study participants. Post-race sniffles are a common problem among endurance athletes.

The team, led by Glyn Howatson at Northumbria University and Lygeri Dimitriou at Middlesex University, found that marathon runners, who consumed the tart cherry juice had lower markers for inflammation than a placebo group at 24 and 48 hours post-marathon and had no reported incidences of upper respiratory tract symptoms (URTS) up to 48 hours after the race. For the runners who did not drink the tart cherry juice, 50 percent suffered from URTS.

Howatson said that many athletes can suffer from colds and sore throats following strenuous bouts of exercise, like marathon running and triathlons. This is the first study to provide encouraging evidence of the potential role of Montmorency tart cherries in reducing symptoms associated with the development of exercise-induced respiratory problems.

He added that researchers should be looking at all the potential ways they can help athletes recover from strenuous exercise, and protection of the respiratory system is another dimension.

The authors conclude that the results of this pilot study offer an important new opportunity for research, building on the existing body of evidence providing support for the use of Montmorencytart cherry juice in exercise recovery. They suggest future work should examine the prevalence of URTS beyond 48 hours post-marathon.

The study appears in International Society of Sports Nutrition Journal.

Jun 27
Kiwi blackcurrants good for brain
New Zealand blackcurrants are good for keeping us mentally young and agile, finds a study.

The berries help in managing the mental decline associated with aging populations and also helps people with brain disorders such as Parkinson's disease or depression.

"This study is the first to look at the effects of berry consumption on the cognitive performance of healthy young adults," said Arjan Scheepens, the plant and food research scientist who led the study.

The juice from a specific New Zealand blackcurrant cultivar, 'Blackadder' also reduced the activity of a family of enzymes called monoamine oxidases which regulate serotonin and dopamine concentrations in the brain.

These chemicals are known to affect mood and cognition and are the focus for treatments of both neuro-degenerative symptoms associated with Parkinson's disease and mood disorders, including stress and anxiety.

"This research has shown that New Zealand-grown blackcurrants not only increase mental performance but also reduce the activity of monoamine oxidases," Scheepens said.

"One of the key trends in the food industry is the development of ingredients and foods that have beneficial effects on human health," said professor Roger Hurst, science group leader food and wellness at plant & food research.

The study was published in the Journal of Functional Foods.

Jun 26
Coffee Helps Reduce Risk Of Stroke, Heart Disease
New research suggests that drinking at least three cups of coffee a day can help reduce mortality risk, particularly from stroke and heart disease.

"It is important to acknowledge factors which might have a protective effect against cardiovascular disease mortality," researcher Doutor Antonio Vaz Carneiro, said in a news release. "Moderate coffee consumption could play a significant role in reducing cardiovascular disease mortality risk which would impact health outcomes and healthcare spending across Europe."

The research was based on two 2014 meta-analyses suggesting an association between coffee consumption and reduced cardiovascular disease (CVD) risk. The findings suggested that drinking anywhere between three to four cups of coffee per day is associated with an approximate 25 percent reduced risk of developing type 2 diabetes when compared to consuming none or less than two cups a day.

However, it's important to note how the study's results differed basted on varying populations, suggesting that lower or higher amounts of coffee may benefit certain groups over others. (For instance, two cups a day may provide the greatest protection for a Japanese population while three cups a day is better for populations in the United States and the United Kingdom.)

"It is important to acknowledge factors which might have a protective effect against CVD mortality. Moderate coffee consumption could play a significant role in reducing CVD mortality risk which would impact health outcomes and healthcare spending across Europe," added Professor Doutor Antonio Vaz Carneiro of the Faculdade de Medicine da Universidade de Lisboa, Portugal.

The exact link between coffee consumption and lessened cardiovascular disease mortality risk is unclear at this time. However, areas of interest regarding new research and the topic include anti-inflammatory and antioxidant properties on coffee and the known association between coffee consumption and type 2 diabetes risk reduction as well as CVD mortality rate.

The study results highlight research presented at a Satellite Symposium held during the European Association for Cardiovascular Prevention & Rehabilitation 2015 congress in Lisbon, Portugal, on the subject of "Coffee and CVD Mortality."

Jun 25
Prescription Pill Makes You Forget To Be Addicted To Drugs
Addiction is more complex than a chemical need for a particular substance - it's a conjunction of circumstantial and social cues that remind an addict that they need to take a hit. Now researchers from the University of Texas at Austin have found that a blood pressure medication that's already on the market can help decrease the potency of some of the non-chemical drivers of addiction, according to a study published this week in Molecular Psychiatry.

Studies over the past few decades have shown that a lot of addiction comes down to classical conditioning; just like Pavlov's dogs that salivated because the bell was associated with food, recovering addicts can be pushed back to their substance of choice depending on the people, places, sights, and sounds around them that are associated with their addiction.

In the study, researchers trained rats to associate either a white or black room with a dose of alcohol or cocaine. After they were conditioned, rats always chose the color room associated with their addicted substance. The researchers wanted see if they could break the cycle by giving the rats a drug called isradipine, which blocks the transmission of calcium ions to cells in the body. While isradipine is primarily prescribed to lower blood pressure, other studies have indicated that it may also make the brain more plastic and able to be rewired.

Immediately after taking isradipine, the rats made the same conditioned choice to return to the room associated with the drug. But in the days that followed, they didn't express a strong preference for either room. "The isradipine erased memories that led them to associate a certain room with cocaine or alcohol," Hitoshi Morikawa, a neuroscience professor at UT Austin and an author of the study, said in a press release.

Though there are already treatments on the market that dampen the euphoria of taking a drug, Morikawa says isradipine could be much more effective. And because isradipine is already on the market, FDA approval of the drug to treat addiction could be fast-tracked. However, the researchers do not yet know if the drug is as effective treating addicted humans as it is treating rats.

Jun 24
Inexpensive generic heart disease drugs may treat Ebola
New York: Generic drugs used to treat heart diseases also have the potential to bolster the immune systems of patients with Ebola virus and some other life-threatening illnesses, research has found.

Unlike other medications in development for Ebola, which attack the virus, statins and angiotensin receptor blockers typically used for heart disease work on the host response, or a person's biological reaction to the virus, said lead study author David Fedson, retired professor of medicine at the University of Virginia in the US.

The statin/angiotensin receptor blocker combination was found to help improve survival in 100 Ebola patients treated in Sierra Leone, Fedson said.

"This approach to Ebola treatment has two advantages," Fedson said.

First, it uses inexpensive generic drugs that are widely available in any country with a basic healthcare system, and most physicians who treat patients with cardiovascular diseases are familiar with these medications.

Second, because this strategy targets the host response to infection, these drugs might be used to treat patients with any form of acute infectious disease in which a failure to overcome endothelial dysfunction could lead to multi-organ failure and death, Fedson noted.

In a pilot study, patients were given the drugs atorvastatin (40 mg/day) and irbesartan (150 mg/day) at several hospitals in West Africa.

The researchers found rapid clinical improvement in most patients.

Specifically, the drugs stabilise or restore the integrity of endothelial cells lining the blood vessels.

Endothelial cell dysfunction has been a central feature of human Ebola virus disease, leading to severe fluid and mineral losses, Fedson explained.

The findings appeared in mBio, the online open-access journal of the American Society for Microbiology.

Jun 23
Experimental drug shows promise to treat Alzheimer's
An experimental drug has been found to protect Alzheimer's-inflicted mice from memory deterioration, despite a high-glycemic-index (GI) diet meant to boost blood sugar levels.

The experimental drug from the US-based Eli Lilly and Company mimics the hunger-signalling hormone ghrelin.

"The present results suggest that ghrelin might improve cognition in Alzheimer's disease via a central nervous system mechanism involving insulin signalling," authors of the study published in the journal Scientific Reports wrote.

"With chronic diseases like diabetes and Alzheimer's, you need to do a long-term study," said examiner Inga Kadish, assistant professor at University of Alabama School of Medicine at Birmingham.

"So we did an experiment with the worst-case scenario, a high-GI diet. Alzheimer's disease has 10 or 20 risk factors and some of the strongest risk factors are diabetes or metabolic syndrome."

In contrast to short-term administration of the "ghrelin agonista drug -- which impairs insulin sensitivity and glucose tolerance, which are signs of metabolic syndrome and diabetes -- the researchers found that the long-term ghrelin agonist treatment did not impair insulin signalling and glucose tolerance in Alzheimer's disease mice fed with a high GI diet.

In the study, the Alzheimer's disease-model mice showed a deterioration in spatial learning as they turned older -- in other words, they got lost when trying to swim to a platform hidden just beneath the water surface that they previously were trained to find in a four-foot-wide pool.

The test mice fed with the ghrelin agonist and the high-GI diet showed long-term cognitive enhancement in this water maze test as compared to the mice fed with a normal diet or high-GI diet only.

The test mice also showed more activity, reduced body weight and fat mass. They also showed a beneficial impact of the long-term ghrelin agonist treatment on insulin signalling pathways in hippocampal brain tissue.

Alzheimer's patients show significant shrinkage of the hippocampus, a part of the brain cortex that has a key role in forming new memories.

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