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Apr18

SOY SAUCE MOLECULE HAS GOT ANTI HIV VIRUS ACTIVITY AND MAY PROOVE BETTER THAN TENOFOVIR TO KILL HIV / AIDS VIRUS

PROF.DRRAM ,HIV/AIDS,SEX Diseases,Deaddiction & Hepatitis Expert 
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For HIV patients being treated with anti-AIDS medications, resistance to drug therapy regimens is commonplace. Often, patients develop resistance to first-line drug therapies, such as Tenofovir, and are forced to adopt more potent medications. Virologists now are testing the next generation of medications that stop HIV from spreading, and are using a molecule related to flavor enhancers found in soy sauce, to develop compounds that are more potent than Tenofovir.
n 2001, a Japanese soy sauce company inadvertently discovered the EFdA molecule while trying to enhance the flavor of their product. The flavor enhancer is part of the family of compounds called "nucleoside analogues" which is very similar to existing drugs for the treatment of HIV and other viruses. EFdA samples were sent for further testing, which confirmed EFdA's potential usefulness against HIV and started more than a decade of research.
In their latest study, Sarafianos and his colleagues, including researchers from the University of Pittsburgh and the National Institutes of Health, helped define how EFdA from SOY SAUCE works on a molecular level and kill hiv virus.
Sarafianos said. "EFdA works extremely well on HIV that is not resistant to anti-AIDS drugs, it also works even better on HIV that's become resistant to Tenofovir."



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