Antibiotic-Resistant Infections Doubled Since 2007 in Europe

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The way antibiotic resistance is growing even in developed countries ,it wanrs us to take immediate steps to control it by using antibiotics only when it is needed not to use it in every prescription as practised now.More than 33,000 people died from antibiotic-resistant bacterial infections in the European Union and European Economic Area (EU/EEA) during 2015, a study has found. The estimated burden of these infections has doubled since 2007 and was similar to the combined burden of influenza, tuberculosis, and HIV.

                        Most of the estimated burden was in hospitals and other healthcare settings, suggesting an "urgent need to address antimicrobial resistance as a patient safety issue and the need for alternative treatment options for patients with such infections who have comorbidities or are otherwise vulnerable (eg, because of their poor immune system or age)," the authors explain.

Alessandro Cassini, MD, from the European Centre for Disease Prevention and Control, Solna, Sweden, and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands, and colleagues published their findings online November 5 in The Lancet."Strategies to prevent and control antibiotic-resistant bacteria require coordination at EU/EEA and global levels. However, our study showed that the contribution of various antibiotic-resistant bacteria to the overall burden varies greatly between countries, thus highlighting the need for prevention and control strategies tailored to the need of each EU/EEA country," the researchers write.

 
                  The investigators estimated the incidence of infections with 16 antibiotic resistance-bacterium combinations from European Antimicrobial Resistance Surveillance Network 2015 data. They used systematic literature reviews to develop disease outcome models for five types of infection and used Monte Carlo simulations on 2400 disease models to provide estimates of disability-adjusted life-years (DALYs).The researchers estimate there were 671,689 (95% uncertainty interval [UI], 583,148 - 763,966) infections with antibiotic-resistant bacteria in 2015.Of those, 63.5% were linked to healthcare, causing 72.4% (23,976 of 33,110) of attributable deaths and 74.9% (127 of 180) of DALYs per 100,000 population.

"                This finding suggests that the health effects of infections with antibiotic-resistant bacteria predominantly occur in hospitals and other healthcare settings," the researchers write.