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Category : Hormones
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Solitary median maxillary central incisor, a clinical predictor of hypoplastic anterior pituitary, ectopic neurohypophysis and growth hormone deficiency
Clinical evaluation of a 5-year-old boy seeking medical
advice for micropenis was detected to have solitary
median maxillary central incisor (SMMCI), short stature[height: 95.2 cm; < 3rd percentile; standard deviation score
(SDS): – 2.57; target height SDS: – 0.63], small face, low set
ears, depressed nasal bridge, prominent forehead and
stretched penile length of 2 cm . He was born
at term of breech delivery with an uneventful perinatal
history. Investigations were significant for delayed bone
age (3.5 years; Greulich-Pyle), low insulin like growth
factor-1 (IGF-1) (41 ng/mL; normal, 50 – 286), GH deficiency
(post clonidine 100 μ g peak growth hormone: 1.2 ng/mL;
normal > 10 ng/mL), hypoplastic anterior pituitary (white
arrow; partial empty sella), stalk agenesis and ectopic
neurohypophysis (EN) located in tuber cinereum (black
arrow) on MRI. Optic nerve, olfactory bulbs,
corpus callosum and septum pellucidum were normal. GH
replacement resulted in an 11 cm height gain in 1 year.

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A Bearded Indian Female: A Rare Presentation of Cushing's Syndrome
A 16-year-old Indian girl presented with increased facial
hair growth, weight gain, amenorrhea and generalized
weakness for the last 3 months. On examination she was
found to have severe hirsutism, her modified Ferriman-
Gallwey score was 24/36, she had broad purple striae on
abdomen, hypertension and proximal myopathy. On
investigations, the patient was found to have ACTH
dependent Cushing's syndrome.

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Mauriac syndrome: A rare complication of type 1 diabetes mellitus
Mauriac syndrome is characterized by dwarfi sm, obesity
and hepatomegaly in patients with insulin-dependent
diabetes mellitus. It is associated with poor control of
type 1 diabetes mellitus (T1DM) in adolescents, and may
present as obesity, hepatomegaly, cushingoid facies and
elevated transaminases.[1] It is typically associated with
growth failure and delayed pubertal maturation, which
should alert the physician over insuffi cient management of
diabetes mellitus and the related development of Mauriac
syndrome, although these can be reversed with good
glycemic control.[2]

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Restoration of sinus rhythm following levothyroxine treatment in a case of primary hypothyroidism presenting with atrial fi brillation and pericardial effusion
A 72-year-old man presented with palpitation, dyspnea, and chest discomfort. Initial investigations revealed atrial fi brillation (AF)
and pericardial effusion, further investigations unraveled primary hypothyroidism (thyroid stimulating hormone) of 34.7 IU/ml and
total thyroxine (T4) of 5.57 g/dl). Treatment with levothyroxine led to resolution of symptoms, AF, and pericardial effusion.

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Acromegaly presenting as hirsuitism: Uncommon sinister aetiology of a common clinical sign
Hirsuitism though not uncommon (24%), is not considered to be a prominent feature of acromegaly because of its lack of specificity
and occurrence. Hirsuitism is very common in women of reproductive age (5-7%) and has been classically associated with polycystic
ovarian syndrome (PCOS). Twenty-eight year lady with 3 year duration of hirsuitism (Modified Ferriman Gallwey score-24/36 ),
features of insulin resistance (acanthosis), subtle features of acromegaloidism (woody nose and bulbous lips) was diagnosed to have
acromegaly in view of elevated IGF-1 (1344 ng/ml; normal: 116-358 ng/ml), basal (45.1 ng/ml) and post glucose growth hormone
(39.94 ng/ml) and MRI brain showing pituitary macroadenoma. Very high serum androstenedione (>10 ng/ml; normal 0.5-3.5 ng/ml),
elevated testosterone (0.91 ng/ml, normal <0.8) and normal dehydroepiandrosterone sulphate (DHEAS) (284 mcg/dl, normal 35-430
mcg/dl) along with polycystic ovaries on ultrasonography lead to diagnosis of associated PCOS. She was also diagnosed to have
diabetes. This case presentation intends to highlight that hirsuitism may rarely be the only prominent feature of acromegaly. A lookout
for subtle features of acromegaly in all patients with hirsuitism and going for biochemical evaluation (even at the risk of investigating
many patients of insulin resistance and acromegloidism) may help us pick up more patients of acromegaly at an earlier stage thus
help in reducing disease morbidity.

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Thyroid Gland Removal
What is a thyroidectomy?
A thyroidectomy is surgery to remove all or part of the thyroid gland.The thyroid gland is a small gland in the lower front of your neck. It takes iodine from the food you eat to make hormones. The hormones control the process of turning the food you eat into energy.
When is it used?
You may need to have part or all of your thyroid gland removed if: You have a lump in your thyroid gland that could be cancer. If cancer is found, removal of the gland can keep the cancer from spreading.Your thyroid gland is overactive and making too much thyroid hormone (a problem called hyperthyroidism).Instead of this procedure, other treatments may include:If you have a lump, you may choose to have repeat exams over many months or years and then have surgery if the lump grows. If you have cancer in your thyroid gland, there is some risk that the cancer will spread to other parts of your body.If you have an overactive thyroid gland, medicine and radioactive iodine treatments can usually control the problem. You may need surgery if these treatments do not control your thyroid gland.You may choose not to have treatment. Ask Dr. B C Shah about your choices for treatment and the risks.
How do I prepare for this procedure?
Make plans for your care and recovery after you have the procedure. Find someone to give you a ride home after the procedure. Allow for time to rest and try to find other people to help with your day-to-day tasks while you recover.Follow your provider's instructions about not smoking before and after the procedure. Smokers may have more breathing problems during the procedure and heal more slowly. It is best to quit 6 to 8 weeks before surgery.Some medicines (like aspirin) may increase your risk of bleeding during or after the procedure. Ask Dr. B C Shah if you need to avoid taking any medicine or supplements before the procedure.You may or may not need to take your regular medicines the day of the procedure, depending on what they are and when you need to take them. Tell Dr. B C Shah about all medicines and supplements that you take.Your provider will tell you when to stop eating and drinking before the procedure. This helps to keep you from vomiting during the procedure. Follow any other instructions your healthcare provider gives you.Ask any questions you have before the procedure. You should understand what your healthcare provider is going to do.
What happens during the procedure?
This procedure will be done at the hospital.You will be given general anesthesia to keep you from feeling pain. General anesthesia relaxes your muscles and you will be asleep. Dr. B C Shah will make a cut in your neck just above the collarbone. He or she will then remove all or part of the gland. Lab tests will be done right away during the procedure to check for cancer. Based on the test results, the provider may end the operation or may remove another part or all of the thyroid gland. The cut in your neck will then be closed. Rarely, thyroid cancer spreads to lymph nodes. If this has happened, you will need further treatment.The procedure will take 1 to 3 hours.
What happens after the procedure?
You may be in the hospital for 1 or 2 days. If all or a large part of the thyroid gland was removed, you will need to take thyroid hormone medicine for the rest of your life. If you have cancer, you may need to take radioactive iodine medicine to destroy any remaining thyroid tissue and cancerous cells. Ask Dr. B C Shah:how long it will take to recoverwhat activities you should avoid and when you can return to your normal activitieshow to take care of yourself at home what symptoms or problems you should watch for and what to do if you have them. Make sure you know when you should come back for a checkup.
What are the risks of this procedure?
Dr. B C Shah will explain the procedure and any risks. Some possible risks include:Anesthesia has some risks. Discuss these risks with your healthcare provider.You may have infection or bleeding.The nerves that control your speech may be injured. Damage to the nerves could make your voice hoarse. The damage may be temporary or lifelong.The parathyroid glands may be injured when all of the thyroid gland is removed. The hormones made by the parathyroid glands control the amount of calcium and phosphorus in the blood. You need to have the right levels of calcium and phosphorus in your blood so your nerves and muscles work well. If the parathyroid glands cannot function after the operation, you may need to take calcium pills or hormones.If thyroid cancer is found, it can return to the neck or other parts of the body. Fortunately, removal of the thyroid gland usually keeps this from happening.There is risk with every treatment or procedure. Ask your healthcare provider how these risks apply to you. Be sure to discuss any other questions or concerns that you may have.

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Endocrine Surgery
1)Dorairajan N, Pradeep PV: Vignette Thyroid Surgery: A glimpse into the past. International Surgery 2012
2)Pradeep PV, Jayasree B. Thyroglossal cyst in pediatric population: Apparent differences from adult thyroglossal cyst. Ann Saudi Medicine. Manuscript no: ASM-2012-0125 (In Press)
3)Pradeep PV, Vissa S. Follicular neoplasm involving one lobe of thyroid: is hemithyroidectomy the adequate initial procedure? Ir J Med Sci. 2012 Apr 11
4)Pradeep PV, Jayashree B, Skandha S Harshita.A closer look at laryngeal nerves during thyroid surgery: A descriptive study of 584 nerves. Anatomy Research International {Manuscript ID: 490390-2012 In Press}
5)Pradeep PV, Jayasree B, Ramalingam K. Post total thyroidectomy hypocalcemia in benign goiters: A novel multifactorial scoring system to enable its prediction to facilitate early discharge. JPGM 2012 (In Press)
6)Pradeep PV, Ramalingam K. Familial isolated hyperparathyroidism: Role of Intraoperative PTH assay. Indian J Surgery 2011. Manuscript ID: IJOS-D-10-00418. (Online 1st 12/03/12;
7)Pradeep PV, Matta R. An Unusual Dermoid Cyst of the Neck presenting as Mass in the Lateral Neck. World J Endocr Surg 2012;4(1):26-28
8)Hegde KV, Suneetha P, Pradeep PV, Kumar P. Asymptomatic Thymic Cyst Appearing in the Neck on Valsalva: Unusual Presentation of a Rare Disease. J Clin Imaging Sci 2012;2:11
9)Pradeep PV, Vydehi B. Local recurrence as a first sign of parathyroid malignancy! Need to redefine the criteria for diagnosis of parathyroid carcinoma. Indian J Endocrinol & Metab 2012. (Manuscript ID: IJEM 85-12 In Press)
10)Ragavan M, Renu Kumar T, Pradeep PV, Sattar A. ‘Umbrella sign’ in computerized tomogram to differentiate giant greater omental cyst from ascites. Tropical Gastroenterology October - December, 2013 Volume 34, Issue 4
11)Pradeep PV. State of the art: Surgery for endemic goiter. Langenbecks Arch Surg. 2012 Mar;397(3):491-2
12)Pradeep PV, Jayasree B. Post total thyroidectomy hypocalcemia a multifactorial approach to enable its prediction to enable early discharge. Thyroid 2011;21(S1) A72. (abstract)
13)Pradeep PV, Jayashree B, Renu Kumar T. Reversal of cardiomegaly and cardiac function in Hyperthyroidism. World J Endocr Surg 2011;3(2):101
14)Pradeep PV, Vijayabhasker G. Surveillance and Intervention after thyroid lobectomy. Ann Surg Oncol. 2011 Dec;18 Suppl 3:S308
15)Pradeep PV, Ajith K Benede, Jayashree B, Skandha SH. Harlequin syndrome in a Toxic Goiter: A rare association. Case Report Med 2011;2011:293076. Epub 2011 Jul12
16)Pradeep PV, Jayashree B, Mishra A, Mishra SK. Systematic review of primary hyperparathyroidism in India: the past, present and future trends. Int J Endocrinology 2011;2011:921814: Epub 2011 May 26 doi:10.1155/2011/921814
17)Pradeep PV, Jayashree B. Ectopic thyroid with Hashimotos thyroiditis presenting with goitrous hypothyroidism: Case Report. Eur J Pediatr Surg. 2011 May 3; PMID:21544779
18)P.V. Pradeep, M. Ragavan, Jayashree B, Skanda H Harshita, Ramakrishna BA. Surgery in Hashimoto’s thyroiditis: indications, complications and associated cancers - our experience (Original article) JPGM 2011;57(2):120-22
19)Pradeep PV, Jayashree B. Soap bubble type of calcification in Thyroid: Radiological surprise. Otolaryngol-Head & Neck Surg 2011;144(4):642-43
20)Ragavan M, Haripriya U, Pradeep PV, Sarvavinothini J. Prune belly syndrome with pouch colon a rare association- Case Report and review of literature. Pediatric Health, Medicine and Therapeutics Journal 2011;2:1-4
21)Pradeep PV, Sattar V, Krishnachaithanya V, Ragavan M. Huge Thyromegaly: Challenges in the management. ANZ J Surg. 2011 May;81(5):398-400
22) Kumar T.R., Pradeep PV., Ragavan M. Bilobar Thyroid Agenesis presenting with Adenomatous Isthmus and Hypothyroidism in a 13 year old girl: A Case report. Journal of Pediatric Sciences. 2010;2(2):e21
23)P.V. Pradeep, M. Ragavan, T. Renu Kumar, B.A. Ramakrishna. Diffuse lipomatosis of thyroid with hyperthyroidism: A rare association. J Postgrad Med. 2010 Jan-Mar;56(1):35-6
24)P.V. Pradeep, G.V. Chanukya, M. Ragavan, T. Renu Kumar, B.A. Ramakrishna. Surgery in Hashimoto’s thyroiditis: indications, complications and associated cancers - our experience World J Surg (2009) 33:S227
25)Pradeep PV, Kuldeep S. Central Lymph Node Metastasis: Is It a Reliable Indicator of Node Involvement in Papillary Thyroid Carcinoma? World J Surg. 2010;34(9):2251
26)Pradeep PV, Tiwari P, Mishra A, Agarwal G, Agarwal A, Verma AK, Mishra SK. Pulmonary function profile in patients with benign goiters without symptoms of respiratory compromise and the early effect of thyroidectomy. J Postgrad Med. 2008 Apr-Jun;54(2):98-101.
27)Pradeep PV, Mishra A, Agarwal G, Agarwal A, Verma AK, Mishra SK. Long-term outcome after parathyroidectomy in patients with advanced primary hyperparathyroidism and associated vitamin D deficiency. World J Surg. 2008 May;32(5):829-35.
28)Pradeep PV, Agarwal A, Jain M, Gupta SK. Myasthenia gravis and autonomously functioning thyroid nodule - a rare association. Indian J Med Sci. 2007 Jun;61(6):357-9.
29)Pradeep PV, Agarwal A, Baxi M, Agarwal G, Mishra SK, Gupta SK. Safety and efficacy of Surgical Management of Hyperthyroidism: 15 yr experience from a tertiary care center in a developing country. World J Surg. 2007 Feb;31(2):306-12; discussion 313.
30)Pradeep PV, Mishra A K, Agarwal V , Bhargav PRK , Gupta SK , Agarwal A. Adrenal cysts: an institutional experience: World J Surgery 2006, Vol 30 No: 10; 1817-1820
31)Agarwal V, Agarwal A, AK Verma, Bhargava PRK, PV Pradeep Pheochromocytoma, stroke and myocardial infarction in a 43 year male with good functional recovery; a rare clinical sequele. Indian J Urol. June 2006;22:156-158.
32)Pradeep PV, Sashidharan PK, Akbar MA Cushings syndrome due to a pancreatic islet cell tumour. J Assoc Physicians India1996 Nov;44(11):840.
33)Agarwal G, Pradeep PV, Aggarwal V, Yip CH, Cheung PS. Spectrum of breast cancer in asian women. World J Surg. 2007 May;31(5):1031-40.
34)Arshad F , Pradeep PV, Mishra A, Agarwal G, Mishra SK. We read with interest the article by Brauckhoff et al., in the December 2004 issue of the World Journal of Surgery. World J Surg. 2005 Dec;29(12):1693; author reply 1694.
35) PV Pradeep, Mishra A, Mishra SK. Re: "Islet hyperplasia in adults: challenge to preoperatively diagnose non-insulinoma pancreatogenic hypoglycemia syndrome". World J Surg. 2007 Feb;31(2):442-3; author reply 444-5
36)Bhargav PRK, Pradeep PV, Agarwal V, Verma AK, Mishra A, Agarwal A, Mishra SK. The value of clinical characteristics and breast imaging studies in predicting a histopathologic diagnosis of cancer or high-risk lesion in patients with spontaneous nipple discharge. Am J Surg. 2007 Jan;193(1):141-2
37)Pradeep PV , Agarwal V , Bhargav PRK , Mishra A . “Short stay thyroid surgery” Br J Surg 2005; 92:58-59. Correspondence
38) Bhargav PRK, Pradeep PV, Mishra A. Clinical and biological features in the prognosis of Adrenocortical Cancer: Poor outcome of cortisol secreting tumors in a series of 202 consecutive patients. J Clin Endocrinol Metab 2006; 91: 2650-2655. Correspondence.
39)P.V. Pradeep, Mishra SK, Vaidyanathan S, Nair CG, Ramalingam K, Basnet R. Telementoring in Endocrine Surgery: Preliminary Indian Experience. Telemedicine and e-Health Feb 2006;12 (1) 73-77
40)Pradeep PV, Mishra A, Mohanty BN, Mahapatra KC, Agarwal G, Mishra SK. Reinforcement of Endocrine Surgery Training: Impact of Telemedicine Technology in a Developing Country Context. World J Surg. 2007 31(8) 1665-1671
41)Kapoor L, Basnet R, Pradeep PV, Mishra A, Mishra SK. Integrating telemedicine in surgical applications. CSI communications 2007; 30 (11):17-20
42) Pradeep PV, Mishra A, Kapoor L, Daman R, Mishra SK. Applications of Tele-Health technology in Endocrine Surgery: Indian Experience. Proceedings of the Third IASTED International Conference, May31-June 1st, Montreal, Quebec, Canada. ISBN 978-0-88986-667-6.
43)Pradeep PV, Anjali Mishra, Lily Kapoor, Rajesh Basnet, Gaurav Agarwal, Amit Agarwal, AK Verma, SK Mishra. Surgical sub-specialty growth in Developing country: Impact of Telemedicine technology; A Case study with Endocrine Surgery. Proceedings of 2006, 8th International conference on e-health networking, Application and Services. Healthcom2006 (ISBN:1- 4244-9704-5 pp 34-39 ©2006IEEE)
44)PV Pradeep, SK Mishra. Current concepts in the management of Primary Hyperparathyroidism. Annals of Endocrine Surgery 2006, 9(1): 14-17
45)PV Pradeep, SK Mishra. Preoperative preparation and surgical techniques in adrenal diseases. Annals of Endocrine Surgery 2006, 9(1): 34-38
46)R Riju, PV Pradeep, G Unnikrishnan, C G Nair. Follicular Carcinoma thyroid with macroangioinvasion – A case report. Thyroid care and Research,2(2) May 2005
47)PV Pradeep, P Jacob, RC George, S Vaidyanathan, A Nambiar, AV Susheelan: Concurrent medullary and papillary carcinoma of thyroid: A rare combination. Thyroid Research and Practice 2006 Vol 3, No:1, 20-23.

Book Chapter:

1.SK Mishra, Mishra A, Pradeep PV. Telementoring in Endocrine Surgery Chapter 12,Telesurgery Book, Edited by Kumar S/ Marescaux J (In publication) Springer-Verlag GmbH, Heidelberg/Germany. ISBN no. 978-3-540-72998-3
2.Mishra SK, Pradeep PV, Mishra A (2009). Telementoring in India: Experience with Endocrine Surgery. TeleHealth in the Developing World.1st Edition, London, Royal Society of Medicine Press. ISBN 978-1-85315-784-4(Book Chapter).
1)Pradeep PV (Chief Editor): Rogangal Engane Thadayam (How to prevent diseases) 2011; Jyothy Publishers Thrissur, Kerala. (In Malayalam)

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Juvenile diabetes is one of the most common chronic conditions to affect children all over the world and each day, over 200 children are diagnosed with type 1 diabetes. Although Diabetes is a metabolic disorder, it can have psychosocial effect, if not handled in the right manner. As a long term condition that affects day-to-day living, diabetes can be particularly stressful on the child and parents. Newly detected Diabetes impacts all aspects of a child's life and its management requires the parents to tackle challenges at multiple levels physical, psychological, social and educational. If not effectively addressed, a spectrum of psychological issues ranging from lack of confidence to severe depression may result. However with proper training, learning about diabetes and making small changes in life style as a family, you can live a fairly normal life.As Diabetes affect all most organs of our Body ,it is decribed as Diabetes=flow or excess urine,(diuresis or called as POLYURIA),Mellitus= sweet as urine becomes sweet as sugar is excreted in it once our Blood Sugar level cross 180 mg% our kidney cannot absorb all sugar passing through it as sugar is lost person becomes weak(disabled) and need more food or hungry(POLYPHAGIA) and as with sugar more water or urine is also passed so person becomes more thirsty(POLYPEPSIA),these symptoms are very much seen in Juvenile Diabetes or young children then in Maturity Onset diabetes Mellitus (MODS) which affects mostly above 40 yrs of aged persons and mainly present with Metabolic Syndrome.Diabetes thickened intima of our Arteries because of Atherosclerosis as a result micro vessels or Arterioles becomes thickened and Hypertension develops which causes Kidney changes and chronic Renal Failure,Angina,Ischaemic Heart Disease,heart failure,Blocks etc,cerebro Vascular Accident, Ischaemia in Limbs,Ulcers and infections because of excess sugar in blood as well as inert and less responsive protective pain Nerve Fibres.Pain, Parasthesia,Numbness,Paresis due to radiculopathy are common in Diabetic patient,Ulcers and ischaemia of toes and fingers are serious because of single end arteries .patient also notice Sexual Dysfunction often not asked by doctor to patient and all these leads to depression and many psycho neurotic changes in patient and family members and parent leading to total social unjustment and belief in life leading to suicidal tendency due to despairness and loss of hope in life.

In this article, we examine the need for counseling and the various counseling options that a parent has to help a child and themselves deal with such issues.Becuase we belif that Diabetes is harmful but not invinsible,we can easily control it with modern medicines and change in life style with regular precautions and these children will live a normal life rather a better intelligent life ,only love,assurance and encouragement and help from parents and society is needed.
Counseling the diabetic child
A child diagnosed with diabetes is suddenly thrust into the unenviable position of dealing ith a chronic condition. Starting from dietary restrictions to insulin injections, the child has to come to terms with the all-pervasive impact of this condition. As a result, the child ay suffer from stress. Resentment, fear of being mocked at by peers, a fear of being branded as a 'sick' or 'ill' person, and anger at parental control on diet and activities are ome of the feelings that a child may experience. If allowed to build up, such feelings can have a debilitating effect on the child's mental and physiological health.
Parents can do a lot towards helping the child cope with diabetes. In fact, the attitude of parents plays a great role in forming the child's response to the condition. Paying enough attention to the psychological needs of the child can be as important as providing medication. By following these simple do's and don'ts, parents can empower the child as he/she work on responding to the condition.
Do not be over-protective. Many parents confuse precaution with apprehension and cross the fine line between being protective and over-protective. Understand that diabetes need not stop your child from leading a healthy, active life. Do not deter the child from participating in active sports and games in the mistaken belief that your child has to be protected.
2. Do listen and watch out for cues to your child's state of mind. Loss of appetite, sudden loss of interest in studies, reluctance to go to school, a listless attitude are some signs that your child needs help in coping with the condition.
3. Do not refer to the condition as a disease.It only helps to firm up an opinion that diabetes is to be feared and dreaded.
4. Do discuss the condition, its causes, treatment and precautions to be followed. An understanding about the physiological conditions and changes associated with diabetes will alleviate your child's fears about this condition and will equip him/her with the requisite knowledge to tackle it.
5. Do not express worries about the child's future, especially within earshot of the child.
6. Do not treat the child differently from his/ her siblings. This will only make your child more conscious about his/her condition.
7. Do take every opportunity to stress that diabetes is treatable.
8. Do focus on success stories of fellow diabetics from your child's area of interest - for example, successful cricketers, or athletes who are diabetics. Your child will profit from such role models.
9. Letting some one know about the fact that your child is diabetic should occur as naturally as divulging any other personal fact about yourself. If someone were to notice your child taking a shot and wondered what it was or why it was so, that would be a reason to explain! Don't express being diabetic as a negative thing or something that defines a person. Let it come naturally but definitely don't hide it. Be short, precise and positive while telling about it.
10. Be realistic in the goals set of your child.
11. Do set a personal example. Follow a healthy regimen of diet and exercise yourself to make it easy for your child to adhere to his.
12. Be understanding during the instance that your child deviates from the prescribed routine – your child is still a child and there may be occasions when he she feels the need to bypass the routine.

Counseling partners and caretakers
Juvenile diabetes impacts the entire family, not just the affected child. The parents of a diabetic child are also subject to stress, although for different reasons. In the case of parents, possible stressors are a fear of societal ridicule, apprehension about a girl child's marital prospects, worry about the child's longevity and future and sometimes guilt on not being able to protect the child from this condition. Counselling of parents and caretakers can go a long way in helping them tackle the emotional impact of this condition. While child counselling sessions help to assure the child, reinstate confidence and also infuse the belief that diabetes is a manageable condition, parental counseling seeks to allay the parents' fear regarding their child's future.

External sources of counselling
Depending on the extent of the psychological impact, counselling of the child is therefore not just desirable but even required. Although parents may be able to provide suchadvice, external help and counseling can effectively supplement the efforts of parents.

There are various counseling options available.
These are :
Family physician: The family physician is often the first line of support. The family physician will have an intimate knowledge of the child, his/her interests, and temperament. Further, the family physician enjoys the trust of the parents and the child alike. A talk with the family physician may be a timely confidence-booster.

Friends and family: Advice from friends and family, especially fellow-patients can also be very effective. A family member or friend who is successful and happy, despite such a diagnosis can be a very effective role model.

Online and offline support groups: Online support groups for both children and parents alike, provide a global network of support and also resources that the parents and child can tap into. Online support groups overcome the barriers of distance and allow parents to communicate, share and get answers to mutual concerns on bringing up a diabetic child.
Professional counseling: Where the emotional impact is deeper, professional counseling is not just desirable but required. Where thepsychological impact has resulted in mild or severe Depression,advice from a psychiatric professional is mandatory.
Like MODS this Diabetes is too curable but here oral Medicines like Glipizide,Tolbutamide, Chlopropamide, Gliclazide,Glimperide etc.which stimulate Insulin production from Beta cell of Pnacreas does not work as Beta cells are absent in these children's pancreas,even Peripheral receptors stimulator like Metformin or Pio or Rosigliatazone or Repaglinide or Netaglinide or acrabose,Vobiglose,Majlitol,Vidagliptine or Sitagliptine does nor work.
Sole therapy is Injectable Insulin which may be porcine or Bovine Soluble insulin three times a day (used as cheap but leads to resistance and more lipidostophy ,now a days Human or recombinant tech E.Coli produced soluble Insulin three times or Protamin or Zinc insulin Suspension as Lente or UltraLente Insulin in various mixture proportion with Soluble Insulin 1-2 times used as subcutaneous injections at thigh or at belly part.Now a days prtamine fine preparation as Lispro Insulin and once used Insulin Glargin is used.Insulin Detemir or Expenta Injections are too used.Genetherapy and Stem cells are also coming with Pancreatic Beta cell transplant is also practised in developed rich countries.Insulin pump and Nasal Insulin spray is now also used in our country.

Dealing with diabetes is not just about taking medication, it is about dealing with its invisible and intangible effects. Counselling is one of themost potent tools that parents have to successflly manage the psychological consequences of this condition.
For stories on successful role models for children and more tips to young people on self management, coping and living with diabetes should be written and available to children sothat they never give away rather becomes more courageous to face it with change in life style,control over food and regular medicines and prevention of getting infected with infections and avoiding trauma to toes and nails with every care for any dental or any other minor sugical intervention.Such precautions will allow to lead the Child to lead a normal life with normal development ,activities,education and Social upbringing.

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Our body makes it all the time and it plays a major role .It is not exclusively a female hormone nor is it only a sex hormone. It is infact the precursor to the sex hormone , estrogen and testosterone.It regulates blood sugar, develops intelligence, builds bone and brain activities. It is secreted primarily by the ovaries in females and testes in males.There are no great quantitative differences between men and women ( atleast outside the luteal phase).It was not until 1943 that progesterone was made from plant steroid diosgenin .Once it was established that it could be made like this, biochemists began converting it into other hormones like cortisone, testosterone, estrogen and ofcourse the unnatural progestins and progestogens that masquerades as natural progesterone. There is a misconception that the difference between the natural one (made out of plant ) and the altered is just in their spelling. There is much confusion in the minds of many and even the medical field about this.This is not meant as a condemnation. They are just a busy bunch and it is a specialized subject. It is just as a caution to not take everything you hear about these hormones at their face value. Progesterone has a unique molecular structure whereas progestin and progestogens have their structure altered but the latter may look similar to the real thing.Just as ivy and spinach are both green and leafy.(Ivy quiche anyone?) need any other proof? The fact is progestin behave in radically different ways in our body than progesterone. The only similarity is their ability to maintain the endometrial lining.This also means that they can be patented and sold for exhorbitant prices. progestins are potentially toxic because of their altered molecular structure. Some of the side effects are increased risk of abortion and congenital abnormalities if taken by pregnant women, fluid retention, migraine, asthma, epilepsy, cardiac and renal dysfunction, depression, breast tenderness, nausea, insomnia, cancer, and a drop in progesterone levels.There are long term side effects on adrenal glands, liver , ovaries and in uterine function The key messsage is natural progesterone is just like what your body makes and is a unique substance with unique properties that cannot be faked !

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Bioidentical Hormone Replacement Therapy
Press Release Mumbai

“Our Hormones do not decline because we age, but we age because our hormones decline.”


New research findings increasingly support the belief that extending the lifespan of the human cell would translate into healthier organs, glowing skin and a sharper mind. Anti-Aging medicine is gradually taking centre stage the world over as the wonder cure for a variety of diseases including cancer, obesity, diabetes and heart diseases, among others. It is also believed by researchers that Anti-Aging medicines can not only help to enhance the immune system, increase sexual energy, improve skin tone & texture, increase energy levels and make one look and feel younger, but also extend life.

To keep the Indian doctors updated with the latest practices and procedures in anti-aging medicine, IndoMedicon 2010 will hold a two day conference and certification course on Anti-Aging, Aesthetic & Regenerative Medicine in Mumbai on June 19th & 20th, 2010. The conference will be addressed by Belgium based Dr. Thierry Hertoghe and the US based Dr. Anoop Chaturvedi, the two leading exponents of Anti-Aging medicine in the world.

The conference cum certification course will cover such diverse topics as Scientific overviews, How to incorporate Antiaging in the current practice of a doctor, Status of detoxification programs in current Antiaging and Aesthetic practice, Hormonal Imbalances: Cause for premature aging, Nutraceuticals for Antiaging and Aesthetics among other topics.

“A lot remains to be learned about this process, but the promise is more than enticing,” says Dr. Deepak Chaturvedi, President, INDOMEDICON 2010. But, he adds, anti-aging medicine at its current level also can help treat a variety of illness including obesity, menopause, andropause, memory lapses, wrinkles, sagging skin, loss of focus, fatigue, decreased libido, loss of muscle tone and endurance, age spots, and other conditions commonly associated with aging.

Explaining the concept of anti-aging, he says, “Aging, while inevitable, is a modifiable process. And, contrary to popular perception, anti-aging is not a war against aging but a science that, through proper implementation, delays and prevents the process of aging and one that treats age related disorders. It is about maintaining optimum functional levels and quality of life to modulate the aging process.”

“In medical terms, Anti-aging or Regenerative Medicine is the study of body’s endogenous mechanism of self repair and optimization of reparative system with exogenous interventions and technology. It is a specialty and a field of scientific research, which is aimed at early detection, prevention, treatment and reversal of age related decline in the quality of life,” concludes Dr. Chaturvedi.

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