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Feb12
LIPID PROFILE IN FALCIPARUM MALARIA
TITLE-SERUM LIPID PROFILE IN FALCIPARUM MALARIA & IT’S PROGNOSTIC SIGNIFICANCE
AUTHORS—B.K.BARIK, S.GURU, B.N.PATNAIK,P.DAS


INSTITUTE—I M S & SUM HOSPITAL, BHUBANESWAR
MATERIALS & METHODS---

The present study was conducted among 30 cases of complicated & 30 case of uncomplicated malaria admitted to this Hospital during the period from January 2009 to December 2010.
AIM & OBJECTIVE—



To find out changes in Serum lipid profile in Falciparum Malaria & correlate it with prognostic significance

A control group of 45 cases were taken matching the criterias as far as possible from healthy volunteers.

Cases of DM, CKD &Hypertension were excluded from the study.
Contd….

Serum lipid profile(Total cholesterol, Triglyceride, HDL, LDL, VLDL) were estimated on admission, after diagnosis after 8 hours over night fast.
The method used was Dual Precipitation Method.

All lipid parameters ere repeated after 7 days of treatment of all cases.

Besides all clinical examination & other routine laboratory investigations were done.
OBSERVATION
Age & Sex distribution in Cases and Control
DISCUSSION-

In our study cases belonged to younger group with male predominance.

In complicated cases Renal, Hepatic & CNS involvement was predominant.

In complicated cases TG& VLDL was high that decreased after 7 days of treatment comparing uncomplicated cases.

High TG & VLDL was associated with hepatic & renal dysfunction.
CONCLUSION-

Serum TG can be considered most important prognostic indicator with many variations in lipid fractions.

Serum HDL is also good indicator with low sensitivity but high specificity.

Serum TG level returns to baseline after 7 days indicating response assesment


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Feb10
Advantages of Off Pump Surgery
What are the Advantages of Off-Pump Coronary Bypass Surgery (OPCAB)?
An alternative to traditional CABG is off-pump or beating heart surgery, where surgeons don't use the heart-lung machine. The procedure is also called OPCAB (Off-Pump Coronary Artery Bypass). The surgeons sew the bypasses onto the heart while it continues beating. Various types of heart stabilizers are used to restrain the heart one section at a time so the surgeon can operate on it. The chest is opened through a midline sternotomy incision. After the target coronary vessel is exposed and stabilized, it is occluded and opened. A bridging plastic tube -- which allows blood flow during suturing -- may be placed. The bypass graft is then sutured to the coronary artery.
The potential benefits/advantages of off-pump surgery may include the following:

Reduced need for blood transfusions
Reduced risk of bleeding, stroke and kidney failure
Potential for reduced psychomotor and cognitive problems
High-risk patients with additional diseases like lung disease, kidney failure and peripheral vascular disease may benefit from this kind of operation


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Feb06
Facial palsy
Facial palsy is condition in which there is lesion of the facial nerve and the resultant paralysis in the muscles that it supplies. So there will be following features on the side of lesion:

Loss of facial expression.
Drooping of the face- Low eyelid, eyebrow and corner of mouth sag.
Closing the eye is difficult.
Eating is difficult because food collects in the side of the cheek and fluid seeps out of the corner of mouth.
Speaking, whistling and drinking are impaired.
Non-verbal communication is lost as the patient cannot register the pleasure, laughter, surprise, interest and worry.
The patient tends to sit with the hand over the side of face.
*
There is difference between an upper motor neuron lesion and lower motor neuron lesion of the facial palsy.

A unilateral UMN lesion usually spares the forehead as it is also innervated from the other side of the brain (part of facial nucleus supplying the upper face principally the frontalis muscle receive the supranuclear fibers from each hemisphere); however an LMN lesion affects all of one side of the face.

An upper motor neuron lesion causes weakness of lower part only of face on the side opposite the lesion. The frontalis muscle is spared; the normal furrowing of the brow is preserved, and the eye closure and blinking are not affected. The earliest sign is simply slowing of one side of the face, for example on baring the teeth or smiling.
Moreover, in upper motor neuron lesion there relative preservation of spontaneous 'emotional' movement (e.g. smiling) compared with voluntary movement.

A unilateral lower motor neuron lesion causes weakness of all the muscles of facial expression on the same side. The face, especially the angle of the mouth, falls, and dribbling occurs from the corner of the mouth. There is weakness of the frontalis and of eye closure since the upper facial muscles are weak. Corneal exposure and ulceration occurs if the eye does not close during sleep. The platysma muscle is also weak.

Causes of facial weakness:

These are as under:
The common cause of facial weakness is a supranuclear lesion (UMN) e.g. cerebral infarction leading to upper motor neuron facial weakness and hemiparesis.
Lesions at four other levels may be recognized by the associated signs.

PONS. The sixth nerve (abducens) nucleus is encircled by the seventh nerve fibers and is therefore involved in the pontine lesions of the nerve, causing lateral rectus palsy.
If there is accompanying damage to the neighboring centre for the lateral gaze (PPRF) and the cortispinal tract, there is the triple combination of:

LMN facial weakness
Failure of conjugate lateral gaze (towards the lesion)
Contra lateral hemi paresis

Causes include pontine tumors (e.g. glioma), demyelination and vascular lesions.
The facial nucleus is affected unilaterally or bilaterally in poliomyelitis and motor neuron disease; the lateral usually causes the bilateral weakness.

CEREBELLOPONTINE ANGLE. The fifth, sixth and eight nerves are affected with the seventh nerve in lesions in the cerebellopontine angle where they are grouped together. Causes are acoustic neuroma, miningoma and secondary neoplasm.

WITHIN THE PETROUS TEMPORAL BONE. The geniculate ganglion (a sensory ganglion for taste) lies at the genu of the facial nerve. Fibers join the facial nerve in the chorda tympani and carry taste from the anterior two third of the tongue. The (motor) nerve to the stapedius muscle leaves the facial nerve distal to the genu.
Lesions of facial nerve within the petrous temporal bone cause:
Loss of taste on the anterior two third of the tongue
Hyperacusis (an unpleasant loud distortion of noise) due to the paralysis of the stapedius muscle
Causes include:
Bell's palsy
Trauma
Infection of middle ear
Herpes zoster (Ramsay hunt syndrome)
Tumors (e.g. glomus tumor)

WITHIN THE FACE. Branches of the facial nerve pierce the parotid gland and supply the muscle of the facial expression. The nerve can be damaged here by parotid gland tumors, mumps (epidemic parotitis), sarcoidosis and trauma. The nerve is also affected in the polyneuritis (e.g. G.B. Syndrome) usually bilaterally.
Weakness of facial muscles also occurs in primary muscle disease and disease of neuromuscular junction. Weakness is usually bilateral. Causes include:
Dystrophia myotonica
Facio-scapulo humeral dystrophy
Myasthenia gravis

Bell's palsy
This is a common acute, isolated facial nerve palsy believed to be due to viral infection (most probably herpes simplex) that causes swelling of the nerve within the petrous temporal bone.

MANAGEMENT:
Spontaneous recovery occurs toward the end of second week. Thereafter, continuing recovery occur. Fifty percent recover within three months. Continuing recovery may take 12 months to become complete. About 15 percent of patients are left with a severe unsightly residual weakness.

Medical:

Steroids (prednisolone 60mg daily reducing to nil over 10 days.)
Acyclovir for viral infection

If there is severe residual paralysis, cosmetic surgery and/or reinnervation (nerve anastomosis of the lingual to the facial) are some times performed after a year has been elapsed.

Physiotherapy:

During the paralysis:

The selection of the suitable physical agent depends upon the experience or the choice of an experienced physiotherapist. Physiotherapist may choose from a number of physical agents available.

Ultrasound is given over the nerve trunk in front of the tragus of ear and in area between mastoid process and mandible. There is no fear of applying ultrasound while doing the treatment of patient with Bell's palsy. The ultrasound is always applied on the side of lesion in front of the tragus of ear & in area between the mastoid process and mandible where the maximum tenderness of the facial nerve is determined by palpation. It is applied in slow circular motion with a starting dosage of 1 watt per square centimeter for 10 minutes. The dosage may be increased on the subsequent sessions if no remarkable improvement is noted. Let me explain that ultrasound waves cannot traverse the bone. That means ultrasound has zero penetration in the bone. Infact, ultrasound waves are reflected away from the bone. So there is no fear in applying the ultrasound on face. (This is only for LMN lesion type)

Low level laser therapy (infrared 808 nanometer wavelength 400 mill watt power for 5 minutes continuous)

Infra-red: Infra red may be applied to warm the muscles and improve the function, but you must ensure that eyes are protected with linens when you are applying infra-red to face. Timing should be for 10 to 20 minutes at a distance usually between 50 and 75 cm.

Ultraviolet Therapy: Formerly ultraviolet was frequently used to give third or fourth degree erythema doses over the facial nerve trunk and in area between mastoid process and mandible (at the point of emergence of facial nerve on face)to combat the infection and inflammation. The type of lamp used for this type of treatment is the Kromayer lamp. The Kromayer lamp is a water cooled mercury vapor lamp which eliminates the danger of infrared burn. It has the advantage that it can be used in contact with the tissue or with suitable applicator it can be used to irradiate a suitable body cavity.

Testing the dosage can be done with Kromayer lamp in contact with the skin, so very small holes are used, e.g. 0.25 square cm. since exposure time need only be very short. It is often useful if the Kromayer lamp has standard dosage time recorded on it for contact and 10 cm. The front of the Kromayer lamp is cleaned with an appropriate solution and when it has had its full 5 minute warming up period the lamp is ready for use. The front of the lamp is held as close as possible to the skin or the target tissue. At least an E4 dosage is given. Treatment could infact be given at a set distance of, say 4 cm.

Microwave diathermy: As far as micro wave diathermy application is concerned, there is strict contra indication for the use of micro wave diathermy for the treatment of face as micro waves can spread randomly and can damage the lens of eye causing the opacity of the lens. So there is no room for the application of micro wave to face.

Short Wave Diathermy: SWD can be safely applied for the treatment of facial palsy at the point of emergence of nerve on the face. The technique used may be monopolar or bi polar. In bipolar technique using the capacitor field method or induction or cable method, the one facial mask electrode is used as an active electrode for applying the rays to face while the second or indifferent electrode used on some distant part of the body (usually cervical or dorsal spinal area) to complete the circuit. In monopolar electrode method only one electrode is used to direct the rays to the target treatment area site and no second electrode is used at all. The treatment time is between 10 and 30 minutes. Shorter sessions are used for mild conditions. Treatment is given on daily basis to produce the required results.

Electrical Stimulation: The only form of electrical current used on face is interrupted direct current (I.D.C.) whether or not there is reaction of degeneration. This is requested only to preserve the bulk of facial muscles and to prevent their atrophy while waiting them to be in function whenever their re innervations arrives in case of axotomesis or reconduction after neurapraxia if the nerve is not damaged completely. There is no room for the use of faradic current use on the face as it could lead to cause secondary contractures of the face. Moreover, most patients find it intolerable on face due to its unnecessary uncomfortable sensory stimulation. The is due to the reason that the faradic current has a frequency of 50 cycles per second, and so produces the tetanic contraction of the muscles that it stimulates. Although for muscle contraction faradic current is surged to produce alternate contraction and relaxation yet the tetanic type of contraction produced by these 50 pulses delivered in just one second, is not required on face. The face muscles are very thin and delicate and could not tolerate this tetanic type of contraction and may be damaged to produce the secondary contractures. If secondary contractures are produced, all form of electrical stimulation should be abandoned temporarily to avoid further damage to the muscles. The face should be gently stretched and massaged.

Heliotherapy: I have found traditional old lay men to use the convex*lens to focus the sun rays to produce the third or four degree erythema dosages to facial nerve trunk and in area between mandible and mastoid process behind the ear and it frequently give dramatic result with excellent recovery of facial palsy.* The treatment was needed to repeat after one week to repeat the same session of the dosage.* Only three or four sessions of this kind were needed to*do the excellent management of the patient.* Infact, it is one kind of heliotherapy treatment which is available from the natural source of power i.e. the sun.** This is*most common form of physiotherapy medicine that is used by*conventional lay men here in Pakistan with excellent results of the treatment.* Please, note that sun rays are a mixture of infra red rays and ultraviolet rays and visible rays on the electromagnetic spectrum. The thermal effect is produced by the infra red portion of the sun rays while the chemical effect like tanning of skin, effect on photographic film, formation of vita. D is due ultraviolet portion in the sun rays. The visible rays which are near to infra red portion on the electromagnetic spectrum produces effects similar to infra red rays. The visible rays which are near to ultra violet portion on an electromagnetic spectrum produces effects similar to ultraviolet rays. The erythema formation is due to ultraviolet portion of the sun rays. Usually fourth degree erythema dosage is required to produce the required therapeutic results.

Iontophoresis: Zinc, potassium iodide or chloride iontophoresis is given to the affected ear to treat the otitis media if there is infection of the middle ear.

Massage: The patient derives great benefit from the massage. Massage may be taught to the patient.
Stroking in the upward, outward direction. It is given from chin upwards to the temple and from the middle of forehead downwards towards the ear. The technique should be gentle but at the same time stimulating.
Slow finger kneading applied over the paralyzed muscles maintains skin suppleness and muscle elasticity. Small circular finger kneading can be given all over the affected side of the face, care being taken not to stretch the muscles.
Tapotement may be administered in the form of tapping quickly and lightly with the finger tips. It must be done very gently over the forehead and superficial ridges, where only a thin layer of muscle covers the bone.
Frictions are given at the point where the nerve enters the face to soften any inflammatory deposit.
Vibrations performed with the tip of one or two fingers can also be used over nerve trunk at this point or they may be administered by placing the whole flat hand on the affected side of face.
These techniques applied daily for 5 minutes or so help to maintain lymphatic and blood flow and prevent contractures.

During Recovery:

PNF techniques are used for re-education:
Quick stretch can be applied to regain raising of eye brow and the movement of the corner of mouth.
The physiotherapist can produce the movement passively and then ask the patient to hold, and then try to produce the movement.
Icing, brushing, tapping or brisk stroking may be applied along the length of the muscles. e.g. Zygomaticus
Exercises:
Look surprised then frown
Squeeze eyes closed then open wide
Smile, grin, and say 'o'.
Say a, e, i, o, u.
Hold straw in mouth-suck and blow
Whistle

Please, add more suggestions and your own point of view regarding the treatment of facial palsy, mail us - info@bprc.in or visit www.bprc.in


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Feb06
The Prehospital Stroke Scale
Do a quick prehospital assessment when in doubt of a stroke event and save a life. Time is brain.
1.) Facial Droop ( have pt show teeth or smile)
-Normal: both sides of face move equally.
-Abnormal: One side of face does not move as well as the other side.
2.) Arm Drift ( pt closes eyes and extends both arms straight out, with palm up for 10 seconds.
- Normal: both arms move the same or both arms do not move at all ( other findings, such as pronator drift may be helpful)
-Abnormal: one arm does not move or one arm drifts down compared to the other.
3.) Abnormal Speech: ( have the patient say " you cant teach an old dog new tricks" ) may use pts primary language( if pt doesnt speak english) using any complete sentence.
Normal: pt uses correct words with no slurring.
Abnormal: pt slurs word, uses the wrong words or is unable to speak.
Interpretation: According to AHA guidelines, if any one of these three signs is abnormal, the probability of a stroke is 72%


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Feb04
Dr Mahesh Desai of MPUH Nadiad selected for the prestigious 2012 AUA Presidential Citation
Dr Mahesh Desai of MPUH Nadiad selected for the prestigious 2012 AUA Presidential Citation


February 1, 2012

Mahesh Ramanlal Desai, MD
Chairman, Dept of Urology
Muljibhai Patel Urological Hospital
Dr. Virendra Desai Road
Nadiad, Gujarat 387 001
India

Dear Dr. Desai:

It gives me great pleasure to officially select you as a recipient of a 2012 AUA Presidential Citation. I am proud to acknowledge your dedication to residency education in India and fostering progressive international relations with the AUA. The resentation of this honor will be made in conjunction with the 2012 AUA Annual Meeting. The award will be presented during the Awards Dinner on Wednesday, May 23, 2012. There are also many complimentary benefits provided by the AUA to you as a recipient of this prestigious award. Enclosed is a letter from Ms. Liz Asplin, Conventions & Meetings Manager, which outlines the travel, hotel and related details for this function.

Announcement of all AUA awards will be promoted in various AUA publications and on our website.

Congratulations and thank you for your contributions to the field of urology and, specifically, to the AUA.

With warmest regards,

Sushil S. Lacy, MD
President, American Urological Association
SSL/nfw
-------------------------
January 31, 2012

Mahesh Ramanlal Desai, MD
Chairman, Department of Urology
Muljibhai Patel Urological Hospital
Dr. Virendra Desai Road
Nadiad, Gujarat 387 001 India

Dear Dr. Desai:

On behalf of the American Urological Association, congratulations on the prestigious Presidential Citation Award you will receive during the 2012 AUA Annual Meeting in Atlanta, Georgia. My name is Liz Asplin, Convention and Meetings Manager, and I will be your main point of contact for all matters associated with your travel to Atlanta to accept this award.
The Annual Meeting will be held from May 19-23, 2012. As an award winner, several complimentary benefits accompany your award including:

 Round trip, coach airfare for you and your spouse/guest to Atlanta, Georgia

 Two (2) nights complimentary accommodations at an official AUA hotel

 Meeting registration for you and your spouse/guest

 Two (2) AUA Welcoming Reception tickets

The AUA Awards Dinner will be held on Wednesday, May 23, 2012 at The Atrium at 200 Peachtree. A formal invitation to this event, where you will receive your award, will be mailed to you next month.

Congratulations again on your outstanding achievement! Should you have any questions or concerns, please feel free to contact me via phone at 410-689-3739 or via email at asplin@auanet.org. I look forward to working with on your plans for Atlanta, Georgia.

Sincerely,
Elizabeth L. Asplin, CMP
Convention and Meetings Manager


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Jan30
Antioxidants in homeopathy
Agaricus muscarius
Calendula off
Carduus mar
Capsicum
Fucus ves.
Selenium
Curcuma Longa


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Jan30
homeopathy for Infants
Syphylinum or Thuja will quiet a new born infant who is crying continuously.

For cyanotic newborn we have remedies like Borax, Cactus, Digitalis, Lachasis, Laurocer.

Oedema of the feeble delicate newborn effecting eyelids, dorsum of hands and feet, progressing, involving entire cutaneous surface as a result of feeble heart muscle where kidneys are normal, Kali.Carb.is best indicated.

Sulphur 30, single dose helps to clear the rash or small eruptions from the skin of the newborn caused due to infected passage during delivery.

Calcarea Phos. And Lapis alba. are useful in cretinism.

Phytolacca calms down the weeping infant due to difficult dentition.

Borax child is anxious during rocking.

Acid Reflux Prblem(vomiting milk) - Phosphorus 30
Abdominal Pain - Chamomilla 30
Abscess/Boils- Belladonna 30
Acidity- Robnia 30
Adenoids - Calc Iod 30
Anaemia -Nat Mur 30
Asthma - Arsenic alb 30 and Ipeacac 30 alternate 4 hrly
Baby Flu - Eupt Perf 30
Bed Wetting - Cina 200
Cry before urination- Lycopodium 30
Cry from unknown cause- Chamomilla 6 or 30
Chicken pox- Rhus tox 30 4 hrly
Colic- Chamomilla 6
Common Cold- Belladona 30
Convultion- Cuprum met 30
Constipation- Alumina 30
Cough in babies- Bryonia alb 30
Dentition- Calc Phos 30
Diarrhoea- Podyphylum 30
Diarrhoea Green- Ipecac 30, Veratum Alb 30, Chamomilla 30 (teething Dirrhoea)
Dysentry- Aloes 30
Earache - Chamomilla
Eczema- Hydrocotyle a 30
Epilepsy- Oeanthus Croc Q 2 drops thrice in a day
Fever - Aconite Nap 30
Food Allergy- Phosphorus 30
Gastritis - Pulsatilla 30
Hydrocephalus- Hell 30
Hydrocele - Pulsatilla
Jaundice- Merc Sol 30, Chelidonium 30, alternate for a month
Joints pain - Rhus tox 30
Measles- Rhus tox 30
Mouth , Tongue ulceration - Merc Sol 30
Obesity child. - Calc Carb 200 weekly one dose
Teeth decay- Floric Acid 6
Teeth pain- Chamomilla 6
Tetanus- Prevention Ledum Pal 200 one dose after any injury
Thrush- Merc Sol 30
Vomiting- Ipecac 30
vomiting Milk- Aethusa 6
worms - Cina 200

The above medicines are for therapeutic purpose only. It's not an alternative to seeing a homeopath physician in real.


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Jan30
Mumps
homeopathic medicine pilocarpine 6


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Jan30
What is homeopathy?
Homeopathy is a system of medicine that treats diseased individuals on the basis of using medicinal substances capable of producing similar changes in the health of a person as that of the diseased person. The term Homoeopathy is derived from the Greek words - homoios, meaning similar, and pathos, mean suffering. Homoeopathy is based on the principle - like cures like. Dr. Samuel Hahnemann, the founder of homeopathy, himself an allopathic doctor (M.D.). Homeopathy was established it in the late 18th and early 19th century by Dr. Samuel Hahnemann. He realised his own school of medicine (allopathy) wasnt helping the patients and spent years researching on homeopathy. The basic principles of Homeopathy are: -

a. A substance that causes symptoms in a healthy person can be used to treat these symptoms when they occur in an ill person.

b. Diluting the homeopathic medicine increases it collative powers and avoids unwanted side-effects.

c. Homeopathy treats the whole person and not just the illness. The totality of the symptoms is considered: Your complete symptom profile is taken into account, including mental, emotional, and physical aspects.

d. Like cures like: Substances that produce symptoms when given in large doses can clear up those symptoms when the substances are given in micro-doses.
http://www.jorhodeshomeopathy.co.uk/jo-blogs/2008/10/like-cures-like.html

e. A single remedy is given: One homeopathic medicine is chosen to perfectly match the totality of your symptoms.

f. A minimum of doses is given: Only a small stimulus is needed to stimulate your innate healing powers.

More at http://drnancymalik.wordpress.com/article/homeopathy-explained/


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Jan30
How does homoeopathy work?
Homeopathic medicines stimulate your body's homeostatic mechanism so your body heals itself by dealing with the sources of your symptoms. This stimulus assists your system in clearing itself of any expressions of imbalance. The homoeopath gives you a medicine or remedy which matches your symptoms as you experience them, and which takes into account you as a person - your individual characteristics emotionally as well as physically.

Here's an example of how this works. Think of your "natural regulator" as your internal temperature gauge. If you go outside and it is very hot, your body will recognize it is too hot and begin to perspire. Your homeostatic mechanism is producing a symptom - perspiration - in an effort to cool down the body. If you go outside and it is very cold, the symptom is shivering. Your homeostatic mechanism is trying to warm the body up by shivering to produce heat.
Think about the last time you were shivering. You could not control it, and you did not stop until you were warm. It is the same way with homeopathic medicines. If you are ill and your body is showing symptoms, the symptoms will not disappear until the source of the symptoms has disappeared.
Homoeopathic main action is through via media of IMMUNE SYSTEM, and in response to antigenic attack on body very specific antibodies are released which destroys the antigenicity of the organisms and there is no drug resistance as such, because own defense systems comes into action each time there is an attack of organisms.

Homoeopathic action begins as the medicine touches the moist surface of tongue from where it directly goes into circulation of a huge network of nerves which is spread like miles in the body system, nerves are spread like electric wires in the body and from the tongue or olfactory nerves it reaches to a very specific point of weakness in immune system and starts correcting or boosting or strengthening it. Likewise you can imagine how accurate the potency and wavelength of the homoeopathic drug, each of which carries a very specific WAVELENGTH and identity and can enter the weak points of a diseased individual in matter of microseconds when the drug and the disease is matched accurately!!! So wrong medicine does not bring about any cure, and is mere waste of effort.

More details at http://drnancymalik.wordpress.com/article/how-homeopathy-works/


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