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Sep10
OVERWEIGHT-WHAT ISTHIS?HOW TO GET RID OF THIS?
Over Weight is now a main issue of great concern in our day to day life,whether child or adult or a retired person or old every body now is concerned for this.It is a known fact that Overweight is related to bad physique,uglylooking,inferiority complex,a psychological complex leading neropsychiatric disease mixed with anxiety,depression, sleepnessness,bad performance in day to day activities,less concern for education,sports ,l azyness and no interst in personal and physical meeting leading to overeating and viceversa gaining more weight.Beside this aspect of Weight concerns in our middle aged and youngesters,it is of our concern in aged person as it is directly related to Diabetes,Hypertension(High BP)leading cause of more hear attack,Chest pain,Storke and paralysis, Kidney Failure,clogging and blockage of Arteries, changes in vision,sedantry habits,addictions, psychosomatic and sexual diseases beside arthritis,pain over heels and knee joinst and over accidents and skin diseases.

I know each and everyone of us (including me) at some point in our lives are fighting the “battle of the bulge”, hence it is a worth writing on this topic.
Another reason for this writing is the fact that notwithstanding the “magical guaranteed weight loss” as advertised as we regularly see in print or electronic media,internet or socalled practitioners of different types like yoga,acupressure,reki,physical educator,gyms and physical training centres, Exercise centres and instrument sellers and companies of different type of weight reducing machines and devices and beauty ayurvedic,homeo and ingenious and allopathic centres are claiming and attracting every set of people and now senior Doctors are running a camp of Obesity reducing surgeries through laproscopes (Mini Hole surgeries )with a surest gurantee of melting down few KGS in few days.But is it so easy! or so safe without any side effects ? Let me be a party pooper here by saying emphatically…there are no and I mean NO SHORT CUTS.EVERY TIME WE RESORT TO THESE DEVICES EITHER MOST OF THE ARE SHORT LASTING OR WE HAVE TO BEAR SOME SIDE EFEFECTS IF WE ARE NOT VERY MUCH DEDICATED FOR OUR EFFORTS TO REDUCE OVERWEIGHT SERIOUSLY,SO WE GAIN WHAT WE LOOSE IN EARLY DEDICATION.

So let us see why this is such a big problem and what are some of the factors that play a role in weight gain. I would call it weight gain rather than obesity because the term obesity does not include overweight people by definition.

This brings us the fundamental question, when would one be called normal / overweight/ obese or morbidly obese? This classification is based on BMI or Body Mass Index, which is basically a product of a person’s bodyweight divided by a person’s height. A BMI of 18-25 is normal, 25-28 over weight, 28-35 obese and above 35 morbidly obese.

You can calculate your BMI using this online link on any health portal website.


Why does one gain weight? This is a question the answer to which each and everyone wants to know, because if we know the answer to this, very easily we can avoid the causes thereby avoiding weight gain.

Sounds pretty simple, doesn’t it?? Sadly it isn’t that simple.

But to take a common analogy that I give to my patients’ weight gain is like a bank balance, there are only to ways to increase your bank balance (weight) either you earn more (increased intake) or spend less (decreased output).

But sadly I’m sure all of us agree it’s easier to gain weight (except for the lucky few who have genetics on their side), than increase your bank balance. Now once we have the grass root level basic fundamental cause of weight gain let us examine a few reasons as to why and how it actually happens.

INCREASED INTAKE / WRONG INTAKE / IMPROPER INTAKE

As you can see from the heading, it is not only increased intake but also the intake of wrong kinds of food and improper intake, which also contributes to weight gain.

1.Over eating: Though most of us tend not to agree to it, it is often the most common cause for weight gain. Every time you have that extra spoonful, it adds up in the long run. It is said that after a meal one should feel that he can have a little more…. that, is the time one should stop. But more often than not, we stop when we feel full and that is already too much.

2. Fast food: Fast food is fast to make and convenient to eat can be eaten on the move but more often than not is full of fats/cheese & salt.
Anyone who has read science in school knows that fat has more calories (9Kcals/gm) as compared to protein (4Kcals/gm) or carbohydrates (4Kcals/gm). So, the more fats you eat the more calories you are putting in. Carbohydrates are easy to absorb and after your basic energy requirements are met, are converted to fat for storage.

Chips – a favorite amongst most is another common cause. An old saying for them, which holds very true, is “ A minute on your lips & a lifetime on your hips”, hence avoid them.
Increased salt intake causes more water retention in the body and hence is also an important factor for weight gain.

3.Improper timing: The time of a meal also is an important factor. Food should be eaten at least 2 hours before one goes to bed to allow digestion to occur properly. So, siesta’s after a heavy lunch or eating just before going to bed are not such good ideas after all.
There is research also to suggest that, the later in the night one eats, the more chances are that all that food is being converted to fat. So, having “ a midnight snack or munchies” is again not such a great idea.

4.Alcohol: Alcohol has often been blamed for gaining weight but the gain in weight is more related to the increased snacking, which goes along with consumption of alcohol.

5.Fizzy Drinks: These are aerated drinks with empty calories, which are of no use and add up to the over all “Bank Balance of Calories”. Instead, substitute it with fresh fruits or fresh lime, which is much healthier but of course try and avoid excess salt or sugar in them.

DECREASED OUTPUT:

This is now turning out to be an important part of the whole weight gain process, especially so in youngsters and children.

1.Sedentary lifestyles: Now with the comfort levels increasing, activity has reduced. We use the lifts instead of stairs, vacuum cleaners instead of brooms, cars instead of walking, etc. The amount of calories burnt per day is decreasing with more mental activity than physical.
Some amount of physical activity is needed daily to keep the Basal metabolic rate higher so that you can burn more calories. Of course though ideal, considering family and work pressures, it is understandable that a regular gymming schedule is not always possible.
But, one can incorporate small things into the daily schedule to increase the output like taking the stairs instead of the lift, walking to the nearby store instead of driving, morning or evening walks, etc which do not take up too much of your time but help in spending those calories.

2. Children especially should have some regular physical activity in their daily schedule or we are going to be waking up to a generation of overweight youngsters. It is already happening in the west and is a major health hazard. We can see it happening around us in India too.

Real games instead of Video Games, fruits instead of chips or pizza & fruit juices instead of a fizzy drink should be the mantra for the kids.

MEDICAL CONDITIONS FOR WEIGHT GAIN:

There are a few medical conditions that can be a cause for weight gain. These are usually hormonal imbalances. The most common being:

1.Hypothyroidism: Here there is a decreased secretion of “Thyroid Hormone” which is responsible to maintain the Basal Metabolic Rate and hence there is a tendency towards weight gain. This is a treatable condition and after proper tests to find out the hormonal levels, replacement of the hormones causes a reduction in weight.

2. PCOD: Poly Cystic Ovarian Disease or PCOD is another condition associated with weight gain. Here again the hormonal imbalances cause weight gain and the weight gain in turn worsens the PCOD. Medical & surgical options are available for treatment of this condition. A curious thing seen here is that weight reduction helps with the gyneacological condition with normalization of hormones.

3. Adrenal Hormonal Imbalance: This also can cause weight gain because of water retention.

WEIGHT GAIN & DIETING

A lot has been written n said about dieting and weight loss. Every other person is an expert in some sort of a diet. But a recent study has brought the proper perspective, as I have been saying for quite some time now, its not what kind of a diet you follow but the total intake versus the total output.

So whether it’s a low carb diet, a low fat diet or an only protein diet, it doesn’t really matter. What matters is,the total amount of calories going in.

Crash Dieting is a not a way to loose weight at all. You might loose weight initially but you are loosing muscle bulk and replacing it with fat. And most of the food that one eats gets converted to fat directly because of the body’s survival mechanisms. Secondly, with crash dieting there is a tendency to alternate binging with crash dieting and this doesn’t help.

So, what one needs is a proper balanced diet according to the work he or she does, which has all the necessary nutrients.

TREATMENT OPTIONS

I’m sure all of us have heard or read quite a bit on the treatment options. I’m not going to discuss exercise, lifestyle modification and diet control which are essential to all treatments as an adjunct.
For the ease of understanding, I will divide the treatment options according to the BMI.

BMI of 25-28(30) – Overweight Category:

This is the category for which we have the most number of options.

1. Isometric Exercise/ Non Surgical Body Contouring – This is an option where in, with the help of targeted muscle stimulation & Infra red waves, isolated areas of the body are treated to achieve targeted contouring and inch loss. Here the patient comes in twice or thrice a week to the center, where the machine does the work for them and helps to achieve targeted contouring.

Very good for people in whom muscle laxity is a cause for bad body contour especially in the tummy area. Also very good immediately post pregnancy to help reduce the flab and tighten the muscles which have become loose post pregnancy and child birth

2. Ultrasonic Lipolysis: This involves breaking down the fat cells directly with the use of a non-invasive ultrasonic wave. The patient comes in once a month for the treatment, which lasts 45 mins to an hour. The released fat has to be reabsorbed and excreted by the body. It works well for small isolated areas like the saddlebags, lower tummy. This doesn’t work for large areas.

3. Injection Lipolysis or MESOTHERAPY: This involves giving multiple injections in the target areas to help dissolve fat in that area. The injection is usually of a derivative of Soya protein, which helps the cell membranes of the fat cells to break down and release the fat into the body. This is absorbed by the body and excreted.

It requires injections maybe once a month for 4 or 5 times. It works well if given properly and for small areas like the double chin or the saddlebags. Contrary to what people might claim it is not for large areas. Complications in the form or small injections abscess or collections of liquefied fat, which may require drainage, are occasionally seen.

4. LASER Lipolysis: This is a minimally invasive procedure which involves insertion of a small LASER probe in the affected area help break down the fat cells in the track of the probe thereby releasing fat into the body which is reabsorbed and excreted. This is also an office procedure and requires multiple sittings maybe a month apart.

Works well again for isolated areas like double chin, cheek fat, saddlebags, arms, etc. Large volume Lipolysis again is technically possible to a certain extent but not practical. The patient does need to use pressure garments, should have the patience to wait for the results for a few months and of course undergo multiple sittings.

5. Liposuction: This is a surgical procedure where a cannula is inserted under the skin by small 1-1.5 cm incisions in hidden areas to suck out the fat. This again is a procedure for body contouring. Though one does loose weight, he will loose more in inches

There are various techniques like the mechanical, ultrasonic, VASER, power assisted. All these are different methods of suction depending on the type of probe used to breakdown the fat cells.

As regards to the technique there is also the tumescent technique which is the preferred technique nowadays and basically involves infiltrating large volumes of saline along with some drugs to help minimize bleeding and trauma to other structures in the vicinity.

Liposuction can also be classified according to the volumes to be removed. Small, moderate or mega liposuctions. Small volume suction can be done under local anaesthesia. Moderate volumes can be done under local anaesthesia with sedation or general anaesthesia depending on the patient’s comfort level. Mega liposuctions require anaesthesia, hospitalizations and in some rare instances blood transfusions.

Internationally, the accepted volumes of fat that can be safely sucked out at one sitting is @ 8% of body weight in men and @ 9-10% of body weight in women. This is because of the fact that men tend to have an equal amount of fat inside the abdomen, whereas in women most of the fat is extra abdominal and also the fat that men have more fibrous fatty deposits. Hence, women are good candidates for liposuction.

Problems after liposuction are because of the swelling. Here as the fat is physically being sucked out, the effects are noticed immediately, but in a few days swelling sets in and takes around a month before significant changes can be felt. This also depends on the areas targeted and the amount removed. Full healing takes around 3-4 months and during this period the patient needs to wear a pressure garment to help the skin shrink. Some amount of unevenness maybe present which gradually settles with time and massages.

Rarely in smokers, there maybe areas of skin necrosis. Sometimes especially with large volume liposuctions, there maybe some collection of fluid called seroma’s which might require drainage.

BMI of 30-35 – Obese Category:

This category is the so-called “Grey Zone” of weight loss treatments. As these patients are not yet candidates for a Bariatric procedure and the procedures for the overweight category cannot fully help in treating these patients. But increasingly we are seeing patients in this category.

In these patients it has to be a combination of procedures and sometimes multiple sittings are needed to get the desired changes.

More often than not we do large volume liposuction in such cases, maybe one or two sittings with a gap of 6 months in between combined with a proper diet and exercise schedule. The procedure of Liposuction has already been discussed.

BMI of 35 and more – Morbidly obese Category:

These patients have other metabolic problems along with the fact that they are overweight. These are candidates for Bariatric procedures that are procedures aimed at reducing the intake drastically (Gastric banding or Sleeve gastrectomy) or reducing absorption of food (Gastric & Duodenal bypass procedures).

These are major surgeries and have to be done in specialized centers and involve a multidisciplinary approach with the involvement of plastic surgeon, gastroenterologist, psychiatrist, dietician, physical therapists, anesthetists, etc. This itself is a topic by itself.

The aim of this blog was to try and bring things into perspective for a person looking at weight loss or to just get in shape. Ultimately, “ a Stitch in time does save Nine”! So the earlier we wake up to the fact that weight is becoming a problem to all of us, the better it is. If not to reduce, at least try and modify our lifestyle and being about some changes in how we do things, it might help prevent the problem from becoming worse, where a much more drastic and major procedure might be required.

As you must have seen in the course of the blog that, this is not a simple topic and I have not even scraped the surface of the problem. But, the aim is to try and simplify things so one can understand what are the little things we can do to bring about a bigger change.

Whatever said and done, all the procedures are only an adjunct to lifestyle modification to get the full benefits in the long run. Change in dietary habits, maintaining a negative intake output balance, increasing physical activity will all go a long way in helping one keep fit and stay healthy.Simple formula is enought your ouput or expenditure should be more than your input or intake,a strong mind with dedication brings change drasitically but one fact is common in India after heart attack or Kidney failure or Stroke many Obese becomes thin dur to strong dedication and confrmed rigid power of determination to reduce weighrt ,so be positive result must come.


So let us bring about the change… by being the change!!!!
DR.D.R.NAKIPURIA
SILIGURI


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Sep07
Advances in Colorectal Cancer Therapy
While colorectal cancer remains one of the most deadly cancers, researchers are making steady progress against this disease. For people living with advanced colorectal cancer and their loved ones, small improvements make a huge difference. We are seeing many patients with metastatic cancer responding well to treatment and living for a longer time. For decades, medications to colorectal cancer were limited to two drugs: 5-Flurouracil and Leucovorin. But in 2004, doctors began to use targeted therapies also. Avastin and Erbitux are mono-clonal antibodies, new generation cancer drugs that can specifically target cancer tumors. The problem with traditional chemotherapy is that it can't be focused--the drug affects both cancer cells and healthy cells alike. Targeted therapies affect the specific mechanisms that allow cancer cells to grow. As a result, they have fewer side effects. Avastin blocks the effect of a substance in the blood that helps tumors to grow new blood vessels. This substance is called Vascular Endothelial Growth Factor (VEGF). By preventing the creation of new blood vessels, the tumor is starved; thus slowing down the tumor growth. Erbitux blocks the effects of a different growth factor called Epidermal Growth Factor (EGF). But these drugs are only used for metastatic colorectal cancers in combination with 5-Flourouracil, Leucovorin and Camptosar. Another turning point in treating colorectal cancer is Adjuvant and Neoadjuvant therapy. Adjuvant therapy is where chemotherapy and radiation are used after surgery. Neoadjuvant therapy is an approach where the treatment is given before surgery to make the tumor smaller and easier to remove. This is more convenient and it gives better results. It is a trend that is gaining momentum around the world. With more drugs to use for colorectal cancers, doctors are now trying them in new combinations and sequences. While new drugs get most attention, surgery remains the standard treatment for people in the early stage of this cancer. People can have inflated ideas about keyhole surgeries, but it is found that for rectal cancer, laproscopic surgery has not shown to be as effective as open surgery. Although these treatment advances are a cause for enthusiasm, we need to keep it in perspective. There are two ways to look at it. You could say that it's great that over the last decade, we have doubled the life expectancy of a person with metastatic colon cancer. On the other hand, you could say that over the last ten years, all we managed to add was about twelve months. Both statements are true. Although the steps might be frustratingly small, we are still moving forward. They may not be flashy, but hopefully with time and research, all of these smaller steps may add up to something big.


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Sep04
NEW RURAL DOCTORS(BRHC)-HOW ARE THEY SAFE?
In UPA II Government ,some Minister are adamant to bring so much new conception in name of serving poor,rural,farmer and unemployed people of our country forgetting basic infrastructure, fasibilty, econmical viability ,its sustainibilty, acceptance,discimination against rich-poor,urban rural etc., and actual its performance in presence of open corruption,expoitation and tendency to earn money and poser forgetting basic Norm and value of Human life and society.Our present Central Health Minister Mr.Gulab Nami Azad first scapped MCI to grab such agency in Ministry clutch to regulate Medical Education,registration and giving license to run or open New Medical Colleges in INDIA ,an Industry of thousand of crores of Rupees.On May03,2010,Ministry bring "CLINICAL ESTABLISHMENT ACT" to regulate private Hospital and Clinics in name of better service to society and poor persons but Government own Hospital and agencies has been exlcuded from any improvement or screening or any desire or will for improvement as no body can check it whcih serve maximum number of people of our country and almost 90% of our poor people.Government agencies intervention and checking will increas more courruption by Babus and bureaucrats making Private hospitals more and more costly as Government cannot run without them as rich ,havenots,these babus,Politicians,Ministers hardly go to govt.hospitals for their treatment. secondly it is mostly run by Qualified Doctors who treat and cure these patients and if they are not relieved or are not treated well their reputation and complains with in present Laws is enough to deal this but Government wants supervision by Bureaucrats not expert in Medical science by bringing License system upbringing advance rich or MNC Centres to exist and closer of small units making Medical treatment more and more costly.
Similiarly "BACHELOR OF RURAL HEALTH CARE(BRHC) COURSE to produce Rural doctors has been prepared by MINISTER' S MCI on the basis of sending more and more Doctors in Rural areas as no Doctor wants to stay in rural areas,socially this theme may appear popuistic but infact it is faraway from true ,now a days under NRHM Scheme many Doctors are serving Rural areas because of good connectivity and communication facilities in rural areas,secondaly a discrimination between rural and urban people regarding dealing patients should not be done as it will not be accepted by rural people who will not like to get treated by these Rural socalled semieduca,if new medical colleges are open in rural areas where rural students should be admitted,or making compulsory of every physician toserve 02-3 years in rural areas as practised in MBBS course in Maharasthra befor getting final registration or before getting permannat service or promotion or adding more seats in medical colleges and giving it to strictly rural students could save our society from such ill educated doctors who need even a training of more than 4and 1/2 yrs to know better such advancing Medical science and where every body has got right to get best and equal oppurtunity atleast in field of Health and Education.When most of our youths are shifting to urban sides from villages because of lack of infrastructure and less development of Agriculture based Business and factories in rural areas and where farmers are doing day light suicide because of unability to run their livehood from agriculture and these Doctors willremain at rural areas appear only bubble declartaion.
On paper this syllabus is for the three-year course and this rural medical practitioners is ready in MCI premise. It promises to do away with what's "unnecessary" in the four-and-a-half-year MBBS course and prepare "hands-on" doctors at the primary level. The Medical Council of India (MCI), which has prepared the syllabus, has differentiated between BRHC and MBBS doctors by not allowing the former to use the prefix 'Dr' to their name. Instead, they will have BRHC suffixed to their name.
. This new category will be drawn from 10+2 students from rural areas/districts and 25 will be chosen district-wise after an exam. They will be trained at community colleges by practicing or retired doctors from nearby district hospitals. Their practice will be confined to that area and registration will be for one year only. The course will include 10 things: Community medicine, internal medicine, pediatrics, surgery, orthopedics, obstetrics and gynecology, ophthalmology, ENT, radio-diagnosis and dentistry. It will be divided into three phases. In the first, students will study the health problems of the community, basic principles of diagnosis and prevention of common rural aliments such as malaria, anemia, hookworm, kala-az ar, TB and diarrhoea. Phase II w ll involve taking patient history, basic clinical examination and management of diseases. They will be tied up with national health programmes. Phase III will deal with training to prevent basic health problems. The curriculum will do away with many unnecessary aspects in the MBBS course such as in pharmacy and anatomy.
Using "DR" is not trheatening to MBBS or any other practising Doctor as Educated Doctors know they got prestige and recognition respect from Society because of their knowledge not because of "DR"word as many teachers and many other practitioner use ths "DR" word before their name but such anme never disturb theri practice or reputation.
Secondly to produce Doctors without basic knowledge of Anatomy(Structure of Our Body Body parts and Organs ,Physiology(Function of our Body's different organs)Pathology(Basic cause of Disease)and Pharmacy(Knowing details of Medicines and their reaction) is like to fdrive an aircraft without knowledge of Airspacing,to drive car,bus,scooter without knowledge of driving and of road,it will kill all passengers and even persons on the road.
Therefore ,Government should think thrice to bring such populistic looking novice lucrative dreams in to action as instead of improving our society such programmes and course will destroy basic fabric of equality in our society and it will be a discovery of Atomic missiles which may give pride to humanity but may devast and finish whole Humanity if Blast takes place willingly or unwillingly.it is not a prestige issue for IMA or MBBS DOctors but it is a prestige for every citizen who has got a right to have good treatment and care whether he stays in rural or urban area.
dr.D.r.Nakipuria


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Sep03
Realistic Tips for Healthy Weight Loss .....
Being overweight is like three or more people riding a scooter or a two wheeler or three or four extra people are stuffed in a car. Both are going to break down either suddenly or gradually, that's sure. As both are carrying extra weight beyond their strength. Our knees are designed as per our height, to carry certain amount of weight. Weight is generally increased due to overeating & sitting idle or lack of activity. These days it's seen that people are working on computers for hours or watching television & having their food, is also one reason behind overeating. But lack of exercise, I feel is more responsible for being overweight. As exercise or physical activity is the process we burn the calories we acquired from food. But first of all you have to judge yourself & decide that you are going to fight for it. How to do it is not difficult.
There is one very simple method to understand whether one is obese or not. Just recollect out of memory the size of your waist line at the age of 18 or 20. If you don't, take help of your family members. If today, it's increased by around 15% than you can relax. Otherwise you should decide that you have to reduce that flab as soon as possible.
There is no need to press panic button. Here are some realistic tips to loose weight for all those interested in living happy & healthy life-long.
How to control excessive eating?
You have to carefully watch your dietary habits & eating pattern first. As crash dieting has corrosive effect & the lost weight bounces back more ruthlessly. So you have to carefully select the food items & might need to alter some of your habits related to it. We should always keep in mind that we must not loose essential nutrients while following dietary restrictions. So we will not discuss much about stop this or that thing type of restrictions.
- Be sure you are drinking lots of clean water throughout the day. This keeps the hunger suppressed & gives the feeling of fullness. Don't remain hungry as this will cause excessive eating at home. You can drink water if away from home or eating joint as it suppresses hunger for some time. At the time of meals drink a glass of water few minutes before joining the dining table. Sit comfortably & eat without hurry.
- As per Ayurvedic concepts, it suppresses "Jatharagni" (Digestive fire) & induces indigestion & constipation. It should ideally be consumed 20 - 20 minutes after meals for a good digestion. Not drinking water imparts a great effect on our digestive system as it helps essential nutrients to get digested. It is proven fact that drinking water during meals causes indigestion as it dilutes digestive juices & natural process of digesting the food properly. So, please stop drinking water, liquids & cold drinks with your meals or immediately after meals.
- Eat like a cow. Eating three big meals is not a good idea at least after forty. Eat five or six small meals is better option as it helps to keep regular flow of energy & keeps excessive hungry feeling away. Eating this way helps to maintain blood sugar levels within limits. Eat fresh vegetables & fruits with two main meals, with lunch & dinner to be precise. Dinner should be light as heavy will adversely affect your sleep.
- Have fruits between main meals so that you are filled with fibers. Having fruits 10 - 15 minutes before meals is always beneficial as it delays the absorption time & keeps you full for a longer time. Eating more fruits or vegetables is always beneficial as it reduces caloric intake.
- Control your craving for snacks, deserts & cold drinks just before, in between or after meals. You can have small sample quantities of these if it's irresistible, that too in initial stage. Otherwise better you forget these. These are the most serious threats to your weight reduction plans.
- It is a fact that we have 20% extra food always. The fact behind is that: it takes around 20 minutes for brain to register that food is on the way. In younger days we are not harmed as we are very active physically moreover need extra energy to grow. Gradually reduce 10% of your dietary intake & make it 20% within 2 - 3 months. If done slowly, you can do it definitely.
- Do try to be vegetarian, but slowly. Initially it will look difficult. Gradually start having vegetarian diet at least 3 - 4 times a week. You should limit animal protein consumption to control cholesterol levels to reduce possibility of landing into trap of cardiac disorders also. To keep protein intake high, start having legumes - peas, grams, lentils & other pulses. One more thing very simple is to avoid mixing animal proteins with starches like breads & potatoes. I'm sure you will gradually start relishing vegetarian delicacies.
How to add exercise to your lifestyle?
It is also one very important part of to achieving the goal of getting in shape. It's simpler than controlling the dietary habits. Here is how to do it gradually & without a pinch.
- Start walking while on a shopping spree. Leave your car at home if the market is within one kilometer or even if a mile. While in office you can walk & handover the document or message personally to your colleague, subordinate or boss.
- Use stairs instead of lift or escalator. Slowly you can add some exercise through this method.
- Brisk walking has numerous health benefits. One of them is reduction in weight apart from it being useful for joint health, cardiac health & immunity. Start walking at any point of time during the day as an when you are empty stomach since 3-4 hours. Go on tracking on weekends.
One final word:
Always keep in mind a law of nature "Human body has an incredible healing ability to repair, realign & recover naturally". It only needs a chance with serious attention, which we shall give. Wellbeing is always in our hands.


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Sep03
"keyhole"-Minimally invasive double valve repair
MI – DVR(Minimally Invasive Double valve Repair)

Rajendra Vasaiya, Mch, Vihar Shah-MD(anesthesiologist)
Sunil vyas,M.Sc,PGDPT (perfusion technologist)

BACKGROUND: Minimally invasive double valve surgery is relatively lesser known in this part of the globe.. Here we are reporting a case of double valve surgery using minimally invasive approach.


METHODS: A 31yrs old female with post CMV(12yrs back), post MTP(22-days back) status with Hb%=7.3gm was admitted for DVR Gradient across aortic valve=55mm Hg with grade II -AR and MVA=0.8 cm. She had past H/O MTP twice due to her cardiac condition. . A 4 inch size skin incision is made. Sternum is cut with oscillating saw up to the 3rd ICS. Adhesion due to previous surgery were removed, adhesion from Aorta,,PA,&RA are also removed very carefully. Cannulation was carried .through femoral artery and two stage venous cannula in to RA Venous cannula was delivered out from the future drains tube site just below xyphoid. 1st cardioplegia was delivered antigrade in to the aortic root, rest were delivered directly in to the ostea . .Fusion between RCC & NCC up to the mid point was released, partial fusion between RCC & LCC also released. Annulus found to be dilated which was tackle later on after mitral valve correction. Mitral valve was approach through aortic aortic opening, LA was also incise. Complete MV was not seen even through this incision due to previous CMV. Through aortic opening and LA MV and its subvalver apparatus were inspected and decided to go for MV commisurotomy and release of chordal and papillary fusion.Valve is check for any leakage . Now aortic annular dilatation is dealt with reduction annuloplasty using 4-0 teflon pledgated prolien suture.t.
Immediate and late post operative period was smooth and uneventful. Ventilator was removed 3hrs after surgery.On day one blood loss was 120ML.Two units of blood was required post operatively.PCM was given as pain killer.Pnt was shifted to the ward on2nd POD ,and was discharged on 4th POD

REASULT: DVR can be carried out without much of the difficulty using minimally invasive approach. .In this particular patient post operative blood loss was significantly low. Requirement of post operative analgesia is also less. It gives patient a sense of INTACT CHEST.

CONCLUSION: Minimally invasive double valve surgery can be carried out without much difficulty with numerous advantages.


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Sep03
Proximal anastomosis in MIDCAB-An enigma, coronary web mastering-a solution
MIDCAB –proximal anastomosis(an enigma)- coronary web mastering a solution

Rajendra Vasaiya, MCh, Vihar Shah,MD, Sunil Vyas,M.sc.PGDPT

BACKGROUND: Distal anastomosis to the coronary arteries may not cause that much problem due to relatively easy accessibility. Method of Exposing aorta and if due to anatomical and hemodynamic limitation aorta can not be expose what other alternatives site are available is explained.


METHOD: once coronary artery is exposed and stabilized distal anastomosis is a relatively easy task. When question of proximal anastomosis arises, through minithoracotomy(from 4th ICS) , where is the aorta? Aorta is no where in the picture. Due to our traditional mind set we look forward to proximal ascending aorta for proximal anastomosis. Technique of exposing proximal ascending aorta is explained. What are the other alternative site and how to carry out proximal anastomosis with alternative site is also explained. A new concept called coronary web mastering along with arterial loop technique is also shown in detailed.

REASULT: with different technique explained above, we have complete and satisfactory proximal anastomosis. Because of not finding suitable site for proximal anastomosis we have never converted our MIDCAB procedure to conventional sternotomy procedure

CONCLUSION: In MIDCAB CABG proximal anastomosis are real challenging compare to distal anastomosis. Over the last 10 yrs we have gradually evolved various alternative site for proximal anastomosis . Though technically challenging these methods are effective for complete triple vessel revascularization through sternal sparing minimally invasive minithoracotomy approach.


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Sep03
Journey through midcab,Tyro to virtuoso
JOURNEY THROUGH MIDCAB (1997 to 2009)
TYRO TO VIRTUOSO (STUDY OF 159 MIDCAB)

BACKGROUND: - MIDCAB CABG in triple vessel disease is remained dream to many Cardiac surgeons. Difficulties and short comes exist. How to overcome and accomplish a complete and satisfactory revascularization is the most important goal of a Bypass surgery. Technical difficulties and its solution are described.

METHOD: - Since 1997, we started sternal sparing MIDCAB CABG. Till 2009 we have done 159 patients.70 patients were operated for SVD (58 CABG, 12 redo CADG), 32 cases for DVD (29 CABG, 3 redo CABG), 57 cases of TVD (55 CABG, 2 redo CABG). For initial two yrs. it was limited to SVD, mostly CTO of LAD. 1st case of redo CABG was carried out in 1999. Gradually field was expanded to DVD and since last 4 yrs. TVD cases are also incorporated. It also includes 10 cases of endarterectomy. One case with CMV and CABG. Patients’ age range between 32 – 92 yrs. LVEF = 25% (10 – 55%), 3 patients with EF of 10% were offered CABG with stem cells implantation. As much as 4 vessels were grafted. Patients overweight have no contra indication. Additional plural adhesion is also not a contra indication. Among TVD 20% had varying degree of left main disease (50 – 96%). 1 patient weighing 114 kg was also operated.

RESULT: - There was 1 mortality in a redo CABG group. The patient died on 6th POD due to VTVF. One case of TVD shows ST- elevation for 24 hrs, post operatively which subsided later on (peri operative MI). 1 patient required re-exploration due to bleeding from mammary bed. Average requirement of BT was 1.5 bottles per patient. Transfusion requirement usually depends upon pre operative HB level. Average hospital stay was 4 days (36 hrs to 6th POD). No major wound complication is seen. Average incision size is 3.5 inches (2.5- 4.2 in.). Conversion to mid sternotomy was required in 1 patient.

CONCLUSION: - Sternal sparing MIDCAB can be carried out in all but cardiogenic shock group of patients. We found it is particularly advantageous to old debilitating patient more so with farer sex group of patient. It can b learnt only by self indulgence. This method is not described anywhere in known literature. It is little time consuming and requires great deal of skill and patience on part of operator.


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Sep02
GREEN TEA-FROM DARJEELING HIMALAYA OR ASSAM VALLEY
Healthy Greens is the sogan which is heard everywhere because we know this green by absobing noxious carbondioxide excreted by all living animals of world and by giving oxygen to breathe, bringing rains,wood,forest,fetilising our soil, conserving soil,forest and human Eco atmoshphere preserve us and our Earth by keeping intact our Glaciers and ozone layers save us from ultra violet radiation of this Universe leaving no hazard of its decomposition like of man made plastic materials.
In this article,we shall like to discuss the importance of a beverage in the form of "TEA" which is most prevalent in our country as well as almost in every part of world where it is consumed by almost every family twice a day or being offered to every guest coming to home/business centre or any other interaction in our day to day personal or social gathering.
Green Tea which is directly plucked as fresh upcoming triplet Leaf from a Tea Bush or plant (First Flush,i.e.,First sesonable tea in month of April May every year from a Plant after a rest of 03-4 months shrugging off its old leaves completely form Hilly tops of darjeeling or Assam Valleys) are very rich source of Many Anti Oxidants which burns fat of our body reduce bad Cholesterol,Open or dilate our blood vessels ,prevent ,Prostate cancer(Prooved by study in Mice from Dr.Chan in USA)Lung cancer reduce recurrence of Breast,Stomach,Colorectal Cancer prevent Strok,Heart Attack and Diabetes Mellitus.This Green Tea leaves like Black tea leaves are not crushed or withered,steamed and fermented and powdered to form Blak tea or Oolong tea but here leaves are dried and preserved for making tea.
For drinking this tea we have to boil one or two or three cups of Water as per our requirement but small preparation is good and then put some Green leaves inside it (or 3/4 tsf or one tsf Green Tea )as per concentration needed and then allowed to get these leaves shocked into this water for few minutes and then we can add sugar or sugar free tablets and lemon inside it (Not MILK AS IT HAS BEEN PROOVED THAT MILK DILUTES THE BENEFICIARY AFFECT OF THIS GREEN TEA OXIDANTS) and allow it to cool for few minutes and then drink it slowly taking few minutes not very hot and not in just few seconds.the Top variety of Tea Garden,More HILLY terrain where water is less logged and stayed but comes and go under cold temperature with high humidity or tea organic where not fertiliser used to produce it are of best variety but their cost some time is very high thousand rupees per kg .Usually Black Tea should be taken twice a day or two cups a day ,it should be used as food supplement not as Drug .It has been prooved that Caffienated Black Tea is more important as it burns our fat and reduce bad cholesterol LDL markedly.
Tea beside containing "Tanins" which are not very useful contain "CATECHINS" OR EGCG(Epigallo catechins 3 gallate ) compond and Antioxidant which is responsible for dilating Blood Vessels,burning Fat (reducing Atherosclerosis,Reducing Cholesterol thus preventing Hear attack,Strok and Prevent cancers ) like other good Anti oxidant substance like red wine,Grapes,Berries,and Dark Chocolate. But out of all these Tea is more consumed in almost every household of our Human world so this should be more included as our foos supplement.

Green tea was first brewed in China, where it was known as a 'miracle medicine'. In her book, Green Tea: The Natural Secret for a Healthier Life, Nadine Taylor states that green tea has been used as a medicine in China for at least 4,000 years.

Today, research shows us how true that ancient claim was. Green tea, with its medicinal properties, is a boon for the health-conscious and a wonder, even to modern science. The benefits of green tea are many as told earlier above but again summarised below:-------------------------
Inhibits Cancer:----------------
The main ingredient in green tea, Epigallocatechingallate (EGCG) inhibits the growth of cancer. The latest good news about green tea comes from a study done at the Karolinska Institute in Stockholm. A team of researchers headed by Dr Yihai Cao found that green tea can block angiogenesis, the development of new blood vessels that tumors need, in order to grow. In an interview, Dr Caoexplained that the polyphenols in green tea prevent angiogenesis, which also explains why green tea is effective in preventing cancer. According to Dr Hasan Mukhtar, professor and research director of Case Western University, Cleveland, studies have shownthat the risk of stomach cancer goes down as consumption of green tea goes up.
Prevents High Blood Pressure and Heart Disease:----

With the chaos of our daily lives, we can do without the added tension of high blood pressure, which can result in heart problems. Scientific studies show that daily consumption of green tea can prevent high blood pressure. 3 to 4 cups of green tea a day, can substantially reduce an individual's risk of heart disease and stroke.
Restricts Buildup of Cholesterol:---------------

We all know that fat and cholesterol are bad for our health. Bur that doesn't stop us from drooling over a sinfully creamy dessert, does it? Now green tea brings along some great news for food freaks. Experiments demonstrate that green tea restricts the excessive buildup of blood cholesteroJ. It reduces the bad cholesterol (LDL) in the blood and increases the levels of positive cholesterol (HDL), thus reducing the chances of heart disease. For years, researchers were puzzled by what they called the 'French Paradox' … the fact that, despite consuming a diet rich in fat, the French had a very low incidence of heart disease. The answer was found to lie in red wine, which contains resveratrol, a polyphenol that limits the negative effects of smoking and fatty diets. In a 1997 study, researchers from the Universiry of Kansas determined that EGCG, strongly present in green tea, is twice as powerful as resveratrol. Which explains why the rate of heart disease among the Japanese, who are regular drinkers of green tea, is quite low, even though approximately 75 % are smokers.
Lowers the Blood Sugar Level:---------------
Let green tea take care of health worries like blood sugar levels. The extract of green tea has the ability to actually lower blood sugar. It is believed that both the EGCG and polysaccharides in green tea are factors in lowering blood sugar.
Strengthens Immune System:------------------
Today, we live life right in the midst of the madding crowd ... with deadlines and schedules that leave no time for ourselves. With its share of ups and downs, our body needs to be strong enough to fight common diseases like the flu and other infections. Green tea helps to strengthen a weak immune system, guarding us from illnesses and infections that take a long time to heal.
Prevents Ageing:========
Oxygen is very important to us, but it can also be a very harmful agent in the form of active or free radical oxygen. One way to slow the ageing process is to prevent the accumulation of active oxygen in our body. This can be done by antioxidants, which are strongly present in green tea.
Oral Hygiene and Dental Care:------------------
Now you can flash that charming smile without worrying about bacteria and bad breath. Fluoride in green tea protects tooth enamel and EGCG reduces the development of bacteria growing in the plaque. Green tea can also kill other oral bacteria, which cause bad breath. It also stimulates the production of saliva and reduces the harmful acids that form in the mouth.
Boon for Dieters:-----------------
Get yourself in shape with a new slimming potion. Yes, green tea can actually help burn fat. In November 1999, the American Journal of Clinical Nutrition published the results of a study at the University of Geneva, in Switzerland. Researchers found that men who were given a green tea extract burned more calories, since green tea helped to excrete more fat.
So Drink To Your Health:--------------------
People who drink green tea daily, have lower rates of heart disease and cancer and a higher life expectancy. Unlike other antioxidants, those found in green tea cause no toxic side effects. Sounds good enough to put the kettle to boil and give green tea a try?Many more good compounds are found in Green Tea but not seen in same quantity and concentration in Black or White Tea (which is powdered or steamed or fermented tea)are found but their direct contribution on organs and tissue Human health system is yet to be discovered .
Dr.D.R.Nakipuria
Ambika Multi speciality Hospital
29 Agrasen road
P.O.Siliguri-734005
Dist:Darjeeling(W.B.)
09434143550,


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Sep01
BUILDING BETTER BONES
Unhealthy habits put today’s children at extreme riskof osteoprosis . here’s how to protect them , and yourself. Every time a child takes a soft drink, he,s laying the groundwork for a dangerous bone disease. No, fizzy and sugary drinks don’t cause osteoporosis. But because they’re often a substitute for a glass of milk , kids and not getting the calcium and vitamin D they need to build a strong skeleton.Many of them also lead a sedentary lifestyle, so they aren’t getting the bone – building benefits of vigorous exercise either. These children aren’t just in jeopardy for brittle bones and fracture decades down the road: They could be risk of osteoporosis at a younger age than ever before .
"parants should view this seriously”
A body of osteoporosis experts trying to spread awareness about this bone crippling disease . “osteoprosis strats in childhood but has consequences later in life.” The condition causes bones to become riddled with holes, like the frame of house that’s been attacked by termites. That can lead to broken bones, which in turn can cause deformity ,chronic pain or disability osteoprosis can even be fatal : up to 25 percent of older people who suffer a broken hip die within a year.

Osteoporosis isn’t just your grandmother’s health threat. Although it strikes over 50million women in india,it also menaces over 12million men and unaccounted million more have low bone mass. “ It’s a silent disease and doesn’t get detected in most causes until after the patiant’s first fracture” osteoporsis cause loss of height , pain in joints and back , fractures and fear of fracture , and can be very depressin. So it is important that we adopt preventive measures to save millions of people .”

These ‘s a new medical understanding of the best ways to protect ourselves – and our children . “ simple lifestyle change and proper nutrition will help save your bones” “ The sooner you get moving the better.”

Do all children need supplements?
Ideally ,kids and adults should get their daily calcium guota through a healthy diet. Taking milk ?Dairy products of all types will do the trick. Other good sources include sardines, indian carp, leafy-green vegitables like ragi (finger millet), soya , calcium-fortified juices and breakfast cereal. Encourage your children to have two to three servings of these bone –bulider daily. And if they shun milk because they think its fattening , let them know the latest research shows the opposite is true :kids with the highest milk consumption are also the slimmest , while those who drink the most sweetened beverages , unsurprisingly , are the heaviest .
“ if your child is getting insufficient calcium from his diet , go for supplements” or consult with urs paediatric rheumatollogist. There are many supplements now avilable in market, inclide flavoured , chewable 250 and 500mg tablets. There are also liquid preparations to choose from .but be warned ! calcium is best absorbed in small amounts so don’t give more than 500mg at a time .” adult lacking in this bone – bulding mineral can take 1000mg daily preferably500 in the morning and 500 at night .

What ‘ D’ can Do ?
Vitamin D is essential for our body so it can absorb the calcium it gets from food supplements , and helps in forming new bones. Are you getting enough vitamin D? The AIIMS study in northern india also found that over 80 % of the children also had moderate to severe vitamin D deficiency . “This is extremely worrying” there’s growing scientific consensus among experts that the current guidelines of 200 IU (international units) for adults under 50 , and 400 to 600 IU for older people , are to low .
Even a little more can only do good there is growing evidence to suggest that lack of vitamin D can lead to a host of illness es like diabites, prostate , colon and other cancer, in addition to osteoporosis”
Unfortunately vitamin D is found in just a handful of foods like egg yolk and cod liveroil. People can get this vitamin naturally through exposure to the sun . it is ironic that although we have ample sunshine in our country studies show indians tend to be deficient in vitamin D . and this more so in the case of urban indians because they spend more daytime indoors than rural folk. So make it a habit to be outdoors in the sun for 20 to 30 minutes just after sunrise or before sunset.
Studies also show that skin production of the vitamin dwindles in older people even if they’re frequently exposed to sun . suggesting that a supplement might be the best way to safeguard their bone health .

A TEST THAT CAN SAVE YOUR LIFE
Because osteoprosis often causes no symptoms at all until a fall snaps a bone , the only way to tell if you have it is via a bone mineral density test . this prosedure is advised for all women over 50

USE IT OR LOSE IT
As you age , you lose bone faster than you produce it .over the five to seven years after menopause , women can lose up to 20 %of their bone mass due to oestrogen deficiency . paying extra attention to bone health can lessen the damage , however . Men are also affected by age – related skeletal loss, but not as dramatically , since their larger frames provide a higher peak bone mass and their hormones don’t plunge after age 50. Our skeleton needs regular exercise at every age to stay strong, but we’re getting more and more sedentary . “Physical activity is very critical for retaining bone mass”. Children and adult should exercise to keep their bones healthy : 60 minutes of physical activity a day for kids and 30 minutes for adults. A combination of weight – bearing routines (such as walking , jogging, stairs-clinbing, or dancing pluse resistance exercise like weight – lifting)is the ideal recipe for bone health .
For children , jumping is a fun way to bone up. The researcher contrasted elementry school girls who took gym classes to those who also did ten minites of high – impact jumping exercise , three times a week. At the end of the two – year study , the jumping exercise group had a nearly five percent increase in bone mass .other weight –bearing exercise with kid appeal include skipping , tennis , and team sports , such as football “ Its never too late to adopt bone – frendly habits – exersise , get enough sunlight , have adequate calcium . this way , we can keep our bones healthy and prevent osteoporosis”

For more information consult with physician or physiotherapist


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Sep01
AUTOIMMUNE DISEASES-CONNECTIVE TISSUE DIORDERS
When Your body Screams No! or you can say when your protective force (Immune System) is unable to protect you became less or no caring for you or
When your immune system turn on itself, there is a war within the body.it means the proteins in the form of B and T Lyphocytes of your body or mixture of Antigen Antibody complex with complement complex becomes allergent to you ,a protein or an organ is no more tolerated by our body or Immune system and it cecomes hyperactive to it itself or on provocation of some external allergens ,it causes Autoimmune Disease and as it mostly involves connective tissue like muscles,joints,Blood vessels etc it is also called as Connective tissue diorder.
As we know this protective Immune system by making either B lymphocytes or Tlymphocytes protects us when ever an acute (Viral fever,Bacterial infection-skin ulcer,pharyngitis, diarrhoea,jaundice)or Chronic infection (TB,Leprosy)invade or attacks us ,they self contain the offending agent either by killing it immediately or converting a protective Antigen Antibody complex making it is totally unharmful for our body.But here this immune sytem which is broken by HIV infections or make less reactive using Immunusupressants like Steroid,Mycopholate,,Tacrolimus,Cycloserine,like medicine in Asthma,Transplant surgery or treating patients with anti cancer drugs which kill Blood cells or lymphocytes the Sanik of our Immune system or Diabetes or any other chronic infection or old age or child age where our Immune system is less reactive leads to somany opputunistic infections to us or our Body cannot control the infections and infections turns into septicaemia leading to more morbidity and mortality.
But in this order this system or its complex antigen antibody becomes injurious to us and produce a variety of diseases,few of them has been enumerated below.Just like a Police officer attacks you instead of protecting you? Or if, instead of getting the bad guys behind bar to protect you, he decides to put you behind bars?
This is exactly what happens when your body's immune system mistakenly turns on your own healthy organs and attacks them, resulting in autoimmune disorders. When the attack is on a single organ system such diseases are called 'organ-specific' autoimmune diseases (e.g., type 1 diabetes), whereas when the attack is more widespread and affects many organs the diseases are termed as 'systemic' autoimmune diseases (e.g. rheumatoid arthritis). Your immune system may also react to a foreign substance that it normally would ignore (akin to a cop arresting an infant) resulting in an immune reaction commonly termed as an 'allergy'. Here are some major autoimmune disorders and how to cope with them.
LUPUS
Diagnosing this disorder can be complicated as Systemic Lupus Erythematosus (SLE) symptoms tend to vary from patient to patient, are unpredictable, and follow an up and down course.
THE DISORDER
Lupus is a chronic inflammatory disease wherein your body's immune system attacks various organs including the joints, skin, kidneys, blood cells, heart and lungs, making it a potentially life-threatening illness. "While lupus is quite rare (affects 1 in 40,000 people), it is a dramatic disease..
WHO’S AT RISK
“Lupus affects young women between 13 and 40 years. "Environmental factors, family history, exposure to oestrogen and smoking, and viral infections are other common risk factors.”
THE SYMPTOMS
These include arthritis, kidney problems, low platelet and WBC counts, psychosis (manic episodes), rashes on face, especially after-sun exposure, mouth sores, and swelling of the lung and heart lining.Rash bilaterl on cheek is diagnostic when localised to this area is also called DLE otherwise SLE when other organs like muscle ,Joints,Lung, Liver, Kidneys and Blood vessels are affected.
RULE IT OUT
This is difficult to diagnose. Doctors will order blood tests to measure your blood cell count, ESR, kidney and liver functions, and the presence of anti-nuclear antibodies (indicative of an autoimmune disease) as well as urine tests to detect increased protein or red blood cells. A false-positive syphilis test may also be indicative of lupus.
HOW TO GET WELL
“About 10 to 15 years ago, the 5-year mortality rates were 80% . But with improved treatment options, 90% of patients survive for 20 years,.Treatment includes immunosuppresants and immunomodulating agents like steroids. "There are many side effects of steroid use, so it is a matter of balancing the side effects of the drug and the disease symptoms,”.
RHEUMATOID ARTHRITIS
Although joint pain and inflammation are the most visible symptoms, this disorder affects every organ in the body; treating it early and aggressively is the best way to tackle the disease.
THE DISORDER
"The name is a misnomer," . Although classified as an autoimmune musculo-skeletal disorder with most visible symptoms like joint pain/inflammation, rheumatoid arthritis (RA) affects every organ in the body. 'We have outstanding medication to treat RA nowadays." low-dose methotrexate (LDMTX) is the 'central anchor drug' for the treatment of RA.
WHO’S AT RISK
Although the cause is unknown, RA is more common in women. Among the confirmed risk factors are gum disease (periodonitis) and smoking.it affects children too and Juvenile Rheumatoid arthritis is a seriuos as adult one.
THE SYMPTOMS
Early diagnosis is very crucial. "Symptoms to watch out for include: joint pain and swelling, long-lasting early morning stiffness, fever, weight loss and fatigue.”
RULE IT OUT
Diagnosis is arrived at after clinical examination of the patients and blood tests to detect
presence of rheumatoid factor and anti-cyclic citrullinated peptide (anti- CCP) antibodies. A negative result for rheumatoid factor is not indicative of lack of the disease as this factor is detectable in only 75 to 80% patients.
HOW TO GET WELL
There has been a “quiet revolution" in treating RA, a. Besides LDMTX, other drugs prescribed may include non- steroidal anti-inflammatory drugs (NSAIDS), steroids, disease modifying anti-rheumatic drugs (DMARDS), and immunosuppresants.
EXPART SPEAK
“An exciting new discovery is that smoking is a trigger for autoimmune genes to become active”
MULTIPLE SCLEROSIS
This condition is characterised by relapses (when new symptoms appear) and remissions (when symptoms improve on their own).
THE DISORDER
Multiple sclerosis (MS) is a disease in which your body's immune system destroys the protective covering on your nerves. This interferes with the communication between your brain and the rest of your body. This ultimately causes irreversible damage to the nerves themselves, which interferes with the functions that are controlled by the nervous system vision, speech, walking etc.
WHO’S AT RISK
“Women are 1.5 to 2 times more likely to get the disease.it manifests itself in younger people between 20 and 30 years of age.”Asian people are less at risk; it typically affects North Europeans." Genetics, infections, and the presence of other autoimmune conditions are also risk factors.
THE SYMPTOMS
These include loss of vision in one eye, weakness/paralysis of legs, arms, head and neck muscles weakness, tremors, fatigue, and difficulty in swallowing or speaking.
RULE IT OUT
The availability of the MRI has revolutionised diagnosis and treatment. "You can spot lesions in the brain very early in the disease" . Other tests include electrical tests that document the velocity of impulses from various parts of the body to the brain and a spinal tap.
HOW TO GET WELL
In many cases, minor symptoms resolve themselves without any treatment. Treatments to control symptoms include immuno-modulating drugs like interferon and glatiramer which slow down the appearance of symptoms and steroids and mitoxantrone to suppress the immune system. However, interferons are very expensive (Rs 25,000 to 30,000 a month) and therefore not accessible to many. Currently, many drugs are in trial and the outlook is optimistic.
TYPE 1 DIABETES
Although most common in children, this form of diabetes (also known as juvenile onset diabetes) is not easily recognised.
THE DISORDER
Type 1 diabetes is a condition where your pancreas produces very little or no insulin, the hormone needed to process sugar to produce energy.
WHO’S AT RISK
Risk factors include family history, genetics, geographical location, exposure to certain viruses, as well as dietary factors like low Vitamin D levels. This disorder is commonly seen in young children (peak age of onset is 12 or 13 years) and in women.
THE SYMPTOMS
“Onset is more dramatic, and if not diagnosed, this condition can potentially be fatal.In a lot of cases, the diagnosis is made when the child presents acute complications. Stay vigilant for symptoms like weight loss, excessive urination, hunger, blurred vision, fatigue, etc.
RULE IT OUT
Diagnosis is primarily done based on patient history and age. Abnormal blood sugar levels show up in a random blood sugar test and a glycated haemoglobin (A1C) test. Specific blood tests to confirm diagnosis include checking for the presence of GAD antibody, islet cell antibody, and insulin auto-antibodies.
HOW TO GET WELL
Life-long treatment with insulin is the only option available currently. Patients are also advised to eat right, exercise, and diligently monitor their blood glucose levels.
THYROIDITIS
This autoimmune disorder is characterised by chronic inflammation of the thyroid gland leading to either hypothyroidism or hyperthyroidism.
THE DISORDER
Thyroiditis is a condition wherein the immune cells attack the thyroid gland causing inflammation. This chronic inflammation leads to thyroid cell damage. Depending on the rapidity of the damage, a patient can develop hypothyroidism or hyperthyroidism.
WHO’S AT RISK
Various factors including heredity, gender (women are more susceptible), age (middleaged women), and viral infections playa role. "There is a 50% concurrence in
identical twins indicating that the trigger is 50% genetic and 50% environmental.
THE SYMPTOMS
Generalised symptoms may include fever, weight loss, puffiness and joint pain. Typical hypothyroidism symptoms include constipation, weight gain, lethargy and dry skin. Typical hyperthyroidism symptoms include cardiac problems, weight loss, diarrhoea and tremors.
RULE IT OUT
Thyroid function tests and blood tests are normally done.
HOW TO GET WELL
Hypothyroidism is treated with synthetic thyroid hormones. Treatment for hyperthyroidism includes drugs to reduce the effect of excessive thyroid hormones. For example, beta blockers may be prescribed to reduce the impact on the heart. Surgery or radiotherapy to destroy the thyroid gland is also an option.
What are allergies?
Allergies are another form of immune system error which occur when your immune system reacts to a foreign substance (allergen) such as pollen, dust, food, or any other allergen that it would otherwise typically ignore. The resulting symptoms can range from minor irritation to a potentially life-threateninq emergency.
Common allergens
• Dust, pollen, mould
• Penicllin-based antibiotics
• Insect bites (bees, wasps)
• Eggs, nuts, dairy products, wheat
RULE IT OUT
• Skin test
• Blood tests
HOW TO GET WELL
Avoid the allergen
Take steroids, antihistamines, decongestants to relieve symptoms
Purified allergen shots
Epinephrine shots in emergencies
CATARACT
HERE LENS PROTEIN OF OUR EYE IN OLD AGE BECOMES REATIVE LEADING TO OPACITY OF lENS LEADING TO LOSS OF NEAR AND DISTANT VISION AND GRADUALLY COMPLETE LOSS OF VISION REQUIRING REMOVAL OF LENS BY CUTTING OR IN PIECEMEAL BY PHACOSURGERYAND PUTTING EXTERNAL GLASSES OR INTRAOCCULAR LENS IMPLANT .
ANKYLOSING ARTHRITIS
Backed with HLAB 27 gene in blood here both Sacroiliac joints gets stiff and rigid and gradually whole spine like a bamboo,affects more male than female ,anti steoid analgesic and physiotherapy is only help.
Psoriatic Arthritis
here a skin infection leading to multiple presentation starting from a bullae to keratineous hypersclrosis with most debilitating incurable skin disease needing stroid and immunosupressants for control with joint and muscleinvolvements need physiotherapy.
Sjogren's syndrome
here all saliva producing glands and lacrimal glands are involved ,patient doesnot have tear or salive in mouth leading to dryness of eye demanding repeated infections and severe xerostomia where digestion of food and deglutation becomes very problematic.
SCLREDEMA
Here mouth and skin of patients becomes thickened as antigen antibody comples settles at subcutaneous tissue leading to a very small stoma of mouth and skins become dry,unstrchable producing ulcers and gradually lung,oesophagus is involved leading to sever respiratory distress and severe dysphagia.
INFLAMMATORY BOWEL DISEASE
here multiple ulcers develops in large colon and lower part of small gut producing severe diarrhoea with pus and mucus in early stage which becomes fatal gradually and can develop internal fistulae or cancer too.
Good pasture Syndrome
here antigen antibody comples settles at nephrons and damaging them leading to renal failure.
therefore these are few Autoimmune Diorders enlisted beside this now a days Antiphospholod Syndrome where Cardiolipin Antibodies appear agains Phoshpholipid of cell wall and produce arteritis,still birth and miscarriage in pregant mother and involves Liver,Kidey,Muscles and joints in adult leading to Heart and lung failure.
More and more research will establish new and new facts more diseases likeAlzehmier and Psychosomatic diseases are also previewd in this category as more research will define Immune system more clearly and its complex agents and factors will be discovered more and more our understanding of Immune system will establish when we shall see that many cancers too will be attributed due to its falacy,so this subject is very vast and this century will establish its more clearly to us and more treatment inform of Gene and Stem cell therapy will come beside good immunosupressants medicines.


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