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Jan26
Female sexual Dysfunctions
A sexual problem is anything that interferes with a woman’s satisfaction with sexual activity. When this happens, it is often referred by health professionals as female sexual dysfunction (FSD).
To understand why sexual problems occur, it is important to understand the sexual response cycle. This cycle is the same in both men and women, although at different rates and, obviously, with different physical changes.
Sexual response cycle: The cycle has 4 steps.
1. Desire (excitement phase) – Desire is a sexual “charge” that increases interest in and responsiveness to sexual activity. You feel “in the mood.” Your heartbeat and breathing quicken, and your skin becomes reddened (flushes).
2. Arousal (plateau phase) – Sexual stimulation–touch, vision, hearing, taste, smell, or imagination–brings about further physical changes. Fluids are secreted within the vagina, moistening the vagina, labia, and vulva. These fluids provide lubrication for intercourse. The vagina expands, and the clitoris enlarges. The nipples become hardened or erect.
3. Orgasm (climax) – At the peak of arousal, the muscles surrounding the vagina contract rhythmically, causing a pleasurable sensation. This is often referred to as the sexual climax.
4. Resolution – The vagina, clitoris, and surrounding areas return to their unaroused states. You feel content, relaxed, and possibly sleepy.
Every woman progresses through the cycle at her own rate, which is normal for her. A sexual problem may occur if any of these stages does not occur.
A. Sexual problems
The types of sexual problems in women correspond to the stages of the sexual response cycle. Inability to achieve any of the stages can interfere with sexual satisfaction and thus create a problem. Any of these can be very distressing for a woman, because everyone deserves a satisfying sex life. They can be distressing for her partner, too, and can lead to problems in the relationship.
Lack of sexual desire: – Lack of interest in sex, or desire for sex, is a common problem in both men and women, but especially in women. Lack of desire stops the sexual response cycle before it starts. Lack of desire is temporary in some people and an ongoing problem in others.
Difficulties becoming sexually aroused or achieving orgasm: – Inability to become sexually aroused is sometimes related to lack of desire. In other cases, the woman feels sexual desire but cannot become aroused. Orgasm may be delayed or does not occur at all (anorgasmia). This can be very distressing for a woman who feels desire and becomes aroused. It can create a vicious cycle in which the woman loses interest in sex because she does not have an orgasm.
Pain during intercourse: – Pain during intercourse (dyspareunia) is not uncommon. Like other sexual problems, it can cause a woman to lose interest in sex. A number of conditions may cause pain and / or discomfort during sexual intercourse. These conditions include:
1. Vaginal Infection: Certain vaginal infections such as vaginal yeast infections and trichomoniasis are often present without noticeable symptoms. However during sexual intercourse, the rubbing motion of the penis against the vagina and genitalia sometimes causes the symptoms of these vaginal infections to intensify causing stinging and burning. Genital herpes sores are another frequent cause of pain during sex.
2. Vaginal Irritation: Many products contain irritants which can cause vaginal irritation leading to discomfort or pain during vaginal sexual intercourse. These include: Any contraceptive foams, creams, or jellies, Allergic reactions to condoms, diaphragms, or latex gloves, Vaginal deodorant sprays, Scented tampons, Deodorant soaps, Laundry detergents in sensitive individuals, Excessive vaginal douching
3. Vaginal Dryness: Vaginal dryness often causes painful sexual intercourse. Normal vaginal lubrication is present for most women; however, during certain times the vagina may be dry and make vaginal penetration painful.
4. Vaginal Tightness: Occasionally this happens when you feel tense, or are not fully relaxed when penetration occurs. Difficulty in penetrating a tight vagina can happen even when vaginal lubrication is not a problem. Often, the first few times you engage in sexual intercourse, the vagina may be tight due to an unstretched hymen and cause pain at the time of penetration.

Sometimes a more severe condition called vaginismus is responsible for vaginal tightness; women with vaginismus experience strong, involuntary muscle spasms of the vaginal muscles during sexual intercourse or vaginal penetration by any object including fingers and tampons.
5. Pain of the Clitoris: The clitoris is the most sensitive part of the female genitalia. Gentle touching or rubbing of the clitoris is extremely pleasurable for some women, while for others it is unbearably painful. Clitoral pain may also occur due to poor hygiene; vaginal secretions may collect under the clitoral hood and if not carefully washed away may lead to pain.
6. Pelvic Pain: Occasionally a women will experience pelvic pain upon deep, thrusting penetration. Many conditions may cause this pain including:
• Tears in the ligaments that support the uterus (causes include problems during childbirth, inappropriately performed abortion, previous violent sexual intercourse or rape)
• Cervical, uterine, or tubal infections such as pelvic inflammatory disease (PID)
• Pelvic adhesions (often the result of previous pelvic surgery or PID)
• Endometriosis
• Ovarian cysts
• Uterine Fibroid Tumors
B. Psychological Factors
Impact of events during childhood and adolescence
Most studies that have assessed the impact of childhood experiences on female sexual dysfunction are methodologically flawed. They rely on retrospective recall, which is particularly problematic when emotional responses to the event as well as the actual occurrence of the event are being reported. However, there have been some probative links between childhood sexual abuse and having a later sexual dysfunction.
Relationship factors
A substantial body of research has explored the role of interpersonal factors in sexual dysfunction among women, particularly in relation to orgasmic response. These studies have largely focused on the impact of the quality of the relationship on the sexual functioning of the partners. Some studies have evaluated the role of specific relationship variables, whereas others have examined overall relationship satisfaction. Some studies have explored events; others have focused on attitudes as an empirical measure of relationship functioning. Subject populations have varied from distressed couples to sexually dysfunctional clients to those in satisfied relationships. Some major areas are relationship conflicts; extra-marital affairs; current physical, verbal or sexual abuse; sexual libido, desire or practices different from partner and poor sexual communication.
Individual factors
There has been little investigation of the impact of individual factors on sexual dysfunction in women. Such factors include stress, levels of fatigue, gender identity, health, extra marital relationship, financial, family or job problems, family illness or death, depression and other individual attributes and experiences that may alter sexual desire or response.
Physical factors
The female sexual dysfunction may occur due to physical factors have ranged from 30% to 40%. The disorders most likely to result in sexual dysfunction are those that lead to problems in circulatory or neurological function. These factors have been more extensively explored in men than in women. Physical etiologies such as neurological and cardiovascular illnesses have been directly implicated in both premature and retarded ejaculation as well as in erectile disorder, but the contribution of physiological factors to female sexual dysfunction is not so clear. However, recent literature does suggest that there may be an impairment in the arousal phase among diabetic women. Given that diabetic women show a significant variability in their response to this medical disorder, it is not surprising that the disease’s influence on arousal is also highly variable. In fact, the lack of a clear association between medical disorders and sexual functioning suggests that psychological factors play a significant part in the impact of these disorders on sexual functioning.
Other factors
• Changes related to menopause
• Communication problems with partner
• Damage to nerves due to surgery or trauma
• Fear of pain, infection, or being pregnant
• Feelings of guilt and shame about sex
• Lack of appropriate stimulation
• Lack of lubrication
• Medication
Medications
A. Medications that cause disorders of desire

Psychoactive medications
Antipsychotics
Barbiturates
Benzodiazepines
Selective serotonin reuptake inhibitors
Lithium
Tricyclic antidepressants

Cardiovascular and antihypertensive medications
Antilipid medications
Beta blockers
Clonidine (Catapres)
Digoxin
Spironolactone (Aldactone)

Hormonal preparations
Danazol (Danocrine)
GnRh agonists (e.g., Lupron, Synarel)
Oral contraceptives
Others
Histamine H2-receptor blockers and promotility agents
Indomethacin (Indocin)
Ketoconazole (Nizoral)
Phenytoin sodium (Dilantin)

B. Medications that cause disorders of arousal
Anticholinergics
Antihistamines
Antihypertensives
Psychoactive medications
Benzodiazepines
Selective serotonin reuptake inhibitors
Monoamine oxidase inhibitors
Tricyclic antidepressants
C. Medications that cause orgasmic dysfunction
Methyldopa (Aldomet)
Amphetamines and related anorexic drugs
Antipsychotics
Benzodiazepines
Selective serotonin reuptake inhibitors
Narcotics
Trazadone (Desyrel)
Tricyclic antidepressants

Diagnostic features
The DSM-IV (American Psychiatric Association) diagnostic criteria for female sexual arousal disorders are outlined here:
A. Persistent or recurrent inability to attain, or to maintain until completion of the sexual activity, an adequate lubrication-swelling response of sexual excitement.
B. The disturbance causes marked distress or interpersonal difficulty.
C. The sexual dysfunction is not better accounted for by another Axis I disorder (except another sexual dysfunction) and is not due exclusively to the direct physiological effects of a substance (e.g., a drug of abuse, a medication) or a general medical condition.

Treatment
A. Provide education
Provide information and education (e.g., about normal anatomy, sexual function, normal changes of aging, pregnancy, and menopause). Provide booklets, encourage reading; discuss sexual issues when a medical condition is diagnosed, a new medication is started, and during pre- and postoperative periods; give permission for sexual experimentation.
B. Enhance stimulation and eliminate routine
Encourage use of erotic materials (videos, books); suggest masturbation to maximize familiarity with pleasurable sensations; encourage communication during sexual activity; recommend use of vibrators, discuss varying positions, times of day or placesetc.
C. Provide distraction techniques
Encourage erotic or nonerotic fantasy; recommend pelvic muscle contraction and relaxation (similar to Kegel’s exercise) exercise with intercourse; recommend use of background music, videos or television.
D. Encourage noncoital behaviors
Recommend sensual massage, sensate-focus exercises (sensual massage with no involvement of sexual areas, where one partner provides the massage and the receiving partner provides feedback as to what feels good; aimed to promote comfort and communication between partners, oral or noncoital stimulation, with or without orgasm.
E. Minimize dyspareunia
Treat the causes of dyspareunia. Ask the patient to use jelly in case of vaginal dryness.

Homeopathic Medication
Dyspareunia : Arg. Nit, Sepia, Nat. mur, Lyss, Platina, Calc phos, Thuja, Acid nit.
Vaginismus : Cact, Plb, Bell, Canth, Puls, Silicia, Lyco, Nat mur, Ignatia, Ferrum.
Aversion to sex: Asar, Caust, Nat mur, Sepia
Anorgasmia : Berberis, Caust, Phos, Ferrum, Sepia
Diminished sexual desire : Caust, Nat mur, Ferrum, Sepia, Acid phos, Graph, Lyco
Dryness of vagina : Nat mur, sepia, Graph, Lycop, Ferrum

Dr. SUNEETH MATHEW BHMS, M.Sc(Psy), M.Phil(Clinical Psy), PG Dip in Criminology & Forensic Science.
Reader, Dept of Practice of Medicine, Hahnemann Homeopathic Medical College, Rasipuram, Salem.
Consultant, Dept of Psychosexual medicine, V-Care Multispecialty Homeopathy, Coimbatore, Baluserry, Mananthavadi and Ideal Speciality Institute, Perambra.
Cell: 09486382600 URL: www.holykings.info


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Jan23
Spirometry for obstructive & restrictive lung disease
Respiratory system performs functions of ventilation (V), perfusion (Q), and diffusion (DL). All respiratory function tests are based on the measurement of these functions. Spirometry measures the echanical function of the lung, chest wall, and respiratory muscles by assessing the total
volume of air exhaled from a full lung (total lung capacity [TLC]) to an empty lung (residual volume). This volume, the forced vital capacity (FVC) and the forced expiratory volume in the first second of the forceful exhalation (FEV1), should be reproducible to within 0.15 L upon
repeat efforts unless the largest value for either parameter is less than 1 L. Flow-volume loop recording is one of the dynamic ventilatory function tests. This is a safe, simple and reproducible. It is performed routinely in general practice. The shape of the flow-volume loop can differentiate between normal or abnormal lung function. Abnormalities like obstructive or restrictive lung conditions can be differentiated. Although these tests cannot give a pathological
diagnosis and assesses the mechanical functional impairment of various respiratory conditions, but they support other respiratory function tests. Moreover, they are important prognostic indicators of disease process and are commonly used to monitor drug therapy. This review explains the interpretation of flow volume curves in health and disease which will provide an
easy guide for both clinicians and physiologists.
Keywords: Spirometry, FEV1, FVC, Obstructive lung disease, Restrictive lung disease


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Jan18
Ozonucleolysis
Ozonucleolysis for slipped/prolapsed Disc

Dr (Maj) Pankaj N Surange
MBBS, MD, FIP
Interventional pain and spine specialist
09871985514

Ozone may be a wonder molecule to the clinicians though its potentials yet to be fully explored. It has role in controlling bacterial, fungal & viral infections including AIDS, treating non-healing ulcers, Rheumatoid and other kinds of arthritis, different kind of skin diseases and many others.

What is ozone?

Ozone is a tri-atomic Oxygen molecule, O3, with a different molecular structure than Oxygen. Its name is derived from the Greek word ozein meaning “to smell”. At room temperature, Ozone is a colorless gas with a characteristic odor (similar smell after thunderstorms, at high altitudes or near the sea etc). At ground level its concentration 0.03 - 0.04 ppm. Ozone in the atmosphere is produced by action of UV rays and thunderstorm on the atmospheric Oxygen; but Medical Ozone is produced from pure medical grade oxygen with the help of high voltage electrical discharge. Medical ozone is a mixture of oxygen and ozone of different concentration. Medical ozone is always freshly prepared on site (in a special generator) for immediate administration. A trained physician according to the medical indication and the patient’s condition determines the exact dose of ozone.

Safety and efficacy of Ozone therapy

Treating patients with ozone is not a new procedure. The first ozone generators were developed by Werner von Siemens in Germany in 1857, and 1870 saw the first report on ozone being used therapeutically to purify blood, by C. Lender in Germany.
During World War 1, ozone was used to treat wounds, trench foot, gangrene and the effects of poison gas. Dr. Albert Wolff of Berlin also used ozone for colon cancer, cervical cancer and decubitus ulcers in 1915. Today, after 125 years of usage, ozone therapy is a recognized modality in many nations: Germany, France, Italy, Russia, Romania, Czech Republic, Poland, Hungary, Bulgaria, Israel, Cuba, Japan, Mexico, and in five US states. It was also used extensively to treat war wounds during World War-II.
It was not popularized before, as ozone resistant materials were not used to produce ozone generators. Also the exact concentration of ozone was unknown. Former Ozone generators are either UV light Ozone generators or plasma type Ozone generators. Here, it was very difficult to know the precise concentration of ozone. Now with the present Corona-discharge Ozone generators, it is possible to know the exact concentration of Ozone. Also, by changing the current or the oxygen flow, Ozone concentration can be precisely modified.
Ozone has been found to be an extremely safe medical therapy, free from side effects. In a 1980 study done by the German Medical Society for Ozone Therapy, 644 therapists were polled regarding their 384,775 patients, comprising a total of 5,579,238 ozone treatments administered. There were only 40 cases of side effects noted out of this number that represents the incredibly low rate of .000007%. Ozone Therapy has been described as the safest known medical therapy.

Indications of Ozone therapy

Among the various diseases presented with pain the following has been treated with very good results; e.g. rheumatoid arthritis, systemic lupus erythemoatosis, scleroderma, polymyositis/fibromyositis, ankylosing spondylitis, osteo-arthritis, Reiter syndrome, psoriasis, synovitis, gout, chrondrocalcinosis, pyrophosphate arthropathy, calcific peri-arthritis, calcific tendinitis, calcinosis and inter-vertebral disc prolapse. In my Pain Clinic I have been treating osteo-arthritis of knee, trigger point injections for fibromyalgia/ Myofascial pain, and inter-vertebral disc prolapse or slipped disc successfully.

How Ozone should be administered?

There are different methods like injections of ozone/oxygen mixture; insufflations through rectum; treating with ozonated water (drinking, dressing wound/ulcers etc.); auto-transfusion of ozonated blood, application of ozonated oil and so on depending on type and site of disease. But for treatment of different pain we use injection of different concentrations of ozone gas only. Ozone molecule is not stable. It has a half-life of 20 minutes only. So, within 20 minutes only half of the original ozone remains, the rest becomes oxygen. Increase in temperature decreases its half-life. For injection it is always freshly prepared on site for immediate administration. Only Ozone resistant syringes can be used for injecting it. The contraindications for treatment with ozone are only a few. They are active bleeding from any site, pregnancy, and active hyperthyroidism.

Mechanism of action

The mechanisms of action of ozone are many. Most of its actions are due to the active oxygen atom liberated from breaking down of ozone molecule. Besides its action as bactericidal, fungicidal, viricidal agent, it activates cellular metabolism, modulates the immune system & increases and activates body's own antioxidants and radical scavengers. In the treatment of pain different other mechanism acts. There is enhancement of circulation. Ozone reduces or eliminates clumping and red cell. Its flexibility is restored, along with oxygen carrying ability (due to the stimulation of 2,3-diphosphoglycerate). Oxygenation of the tissues increases as the arterial partial pressure increases and viscosity decreases. Ozone also oxidizes the plaque in arteries, allowing the removal of the breakdown products, unclogging the blood vessels. All these leads to an increase in the amount of oxygen released to the diseased tissues. There is also reduced formation of inflammatory mediators like different prostaglandins and so there is an anti-inflammatory action.

Ozone in PIVD/Slipped disc

In case of prolapsed inter-vertebral disc (or, slipped disc) different other mechanism acts. Inter-vertebral disc is filled with nucleus pulposus which is a jelly like material which holds water (90% of disc material is water). When ozone is injected into the disc the proteo-glycan bridges in the jelly-like material are broken down and they no longer capable of holding water. As a result disc shrinks and mummified which is equivalent to surgical discectomy and so the procedure is called ozone discectomy or ozonucleolysis. It has been published in ANESTHESIA AND PAIN journals that up to 85% of disc operation can be avoided with these non-surgical interventions. Success rate is about 88% which is comparable to surgical discectomy (50% to 90%). Complications are remarkably low and much less than surgery.

Future

Ozone is gradually gaining popularity in various medical fields especially in pain management. Newer modification in techniques and administration of ozone, more and more publication of scientific materials in the medical journals and animal studies have made it more acceptable to the medical community and gradually it is becoming more popular.


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Jan15
Properties of Chloroquine
Properties of Chloroquine
A few years back, I had written to the Departments of Medicine and Pharmacology, Post-Graduate Institute of Medical Education and Research, Chandigarh, that Chloroquine is anti-viral despite being anti-malaria. The anti-viral properties of Chloroquine, I had emphasized, needed further evaluation and thorough research. There is no doubt that the anti-malaria properties of Chloroquine are pronounced throughout the world, along with its disease modifying properties.
The anti-viral properties of Chloroquine need to be exploited for the benefit of people, especially during the outbreak of viral fever in Chandigarh. Chloroquine, in usual dosage, may be distributed among the residents. It should be swallowed in a single dose before the onset of fever or before the outbreak of viral fever. Moreover, Chloroquine in recommended prophylactic dose doesn’t have any side-effect. It is effective in controlling malaria also.
In my independent findings of Chloroquine during my studies and experience of clinical practice during the past 23 years, I found enthusiastic results of anti-viral properties of this wonderful medicine. This is very much encouraging.
Suffice it to mention that the use of Chloroquine helps prevent the spread of viral fever as a prophylactic drug but not as a therapeutic drug. This needs to be noted. Once there is fever, it takes its own time to subside.
Dr Tejinder M. Aggrwal, National Integrated Medical Association, Chandigarh

25th September, 2002 - The Tribune, Chandigarh

Dr Tejinder M. Aggrwal, MBBS, GAMS
Phoenix Hospital & Diagnostic Centre
SCO 8, Sector 16, Panchkula 134109
Ph: 0172-5054321, 5011333
Fax: 0172-5011334
M: 0-931-610-1112


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Jan14
website on stricture urethra
I have started a special website on Stricture Urethra – www.stricturecure.com . Almost all my patients X-rays (RGU’s & MCU’s) both pre-op, post-op, & follow up results have been uploaded. Once it is fully constructed it will be a unique one with the following attributes :

1. Patients will be able to see their own data, X-rays, & follow up Investigations etc after they log in with a unique ID.
2. A person suffering from stricture urethra will be able to identify himself with all such patients who have the same type of stricture as himself & see their surgical outcome(anonymity being maintained).
3. Any patient/doctor can post/upload the RGU & MCU Images and get expert opinion as to the type of management/surgery required.
4. This is a first of its kind site dedicated to stricture urethra disease.

With Warm regards,
This is my small effort towards Copenhagen, Nopenhagen, Hopanhegen …….. . Our processing is technology driven. We have lowered the use of paper & X-ray films by over 75% thus reducing our carbon footprints.


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Jan06
Adverse effect of Rosuvastatin
REVERSE EFFECT OF ROSUVASTATIN

I have put more than 100 patients on Rosuvastatin (10mg) to treat mixed dyslipidemia and had good results after six months of treatment with diet control and exercise is as follows:
Cholesterol level fell up to 10-15%,
TG level decreased by 5-6%,
LDL Cholesterol decreased upto 10-12% and
HDL level elevated upto 6-8%
Except in 4 patients who had similar results, but their TG level elevated to 60-70% with similar diet control and exercise.
When these patients were put on Fenofibrates (160mg ) with Statin their TG level remarkably improved.


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Jan01
Risk Free Treament For Chronic Psoriatic Patients Found
Risk Free Treament For Chronic Psoriatic Patients Found
Psorcure Treatment Plan for Psoriasis can help patients avoid the side effects of using conventional treatments such as Steroids, Calcipotriol and Methotrexate and Biologics, a study concludes.

(PRWEB) September 8, 2005 -- A recently concluded study puts Psorcure Treatment Plan as a better option in psoriasis management. During the study period it managed the flare-ups effectively after clearing the skin from psoriasis and none of patient under study developed any major side effect symptoms which are generally associated with the use of conventional psoriasis treatments.

It is well known that there are major side effects associated with conventional treatment methods for psoriasis, yet patients are not properly educated about them.

Objective of Study

Conventional Treatments for Psoriasis include use of Steroids, Calcipotriol and methotrexate. Biologics are recently developed treatments. All the four treatment methods are associated with risks of major side effects.

Hyperglycemia (high blood sugar) and glucosuria (high sugar in the urine), Cushing's Syndrome (muscular weakness), High Blood Pressure, Depression, Skin inability to fight infection, Thinning of skin, HPA Axis Suppression are some of the known major risks associated with the long term use or excessive use of tropical steroids.

Dry skin, high blood calcium levels, peeling, rash, red or inflamed skin or hair follicles, skin discoloration, skin wasting, worsening of psoriasis on rebound are the known major risks associated with Calcipotriol.

Methotrexate increases the risk of Liver Disease, Kidney Disease, Diabetes, Asthma, Infection, A stomach Ulcer.

Recently Food and Drug Administration warned doctors about more potential side effects that could be caused by the psoriasis drug Raptiva (Biologic Treatment). The risk includes immune-mediated hemolytic anemia, causing a loss of red blood cells, and serious infections and reduced platelet count, a condition known as thrombocytopenia.

The objective of this study was to see the effectiveness of Psorcure Treatment Plan in managing rebounds and aggravated flare ups and to observe development of major side effects generally associated with conventional treatments for psoriasis.

Study Methodology

30 willing patients were included in this study and were observed for 3 years.

They were monitored during the treatment for effectiveness and after the treatment period for side effects.

Following tests were taken before and after the treatment period to evaluate the effectiveness of treatment.

1..PASSI Score.
2..Skin Biopsy

Following tests and examinations were made at regular intervals during the entire period of study to evaluate the safety of treatment.

Thyroid Profile Test (T3, T4, TSH)
Blood Sugar Test
HDL/LDL ratio
Red Blood Cells and Platelet counts
SGOT and SGPT for Liver
Blood Urea and Serum Creatinine for Kidney

Clinical observations were made and recorded during the study period for following

Nausea/Vomiting, Diarrhea, Alopecia, Blood Pressure, Change in weight, Hair Loss, Dizziness, Depression

Effectiveness of Treatment

The main treatment period was 3-6 months (average 4 months) and it was followed by maintenance treatment for 3 months.

3 patients left the treatment or did not allow us to take biopsy and other tests after the treatment.

In all 27 patients were tested and examined and their results are taken into our study.

Every patient responded to this treatment.

Following changes in skin were observed through skin biopsy.

1.Marked reduction in parakeratosis
2.Marked reduction in Acanthosis
3.Diminished height of rete ridges

Average reduction of 98% in PASSI score was observed.

Rebound or Flare ups

During the entire study period, no patient got any rebound or significant flare up. We recorded 3 years long remission period which indicates the strength of Psorcure Treatment Plan in managing the flare ups and also confirms that this treatment plan does not suppress the immunity level of patients. These results were further confirmed by counting T cells of patients which were found in the normal range during the treatment and even 6 months after the treatment.

It is to be noted here that to get quick results all the conventional treatment methods function with suppressing immunity levels which results in major flare up or rebound as and when patient terminates the conventional treatment method. There is a major difference in the functioning of Psorcure Treatment Plan which restore the immunity levels. The fact that no patient reported any infection during study period is also significant in this regard.

Side Effects

No major side effect was noticed during the study period.

All the results of pathological tests were within normal range through out the study period.The fluctuation range of various tests was +/- 2% during the study period.

The following were significant changes observed during the study period.

Patients were energetic and cheerful in general in contrast to depressed conditions observed at the start of this treatment.

Mean serum creatinine at the start of treatment was 1.0 which was reduced to 0.8 at the end of treatment period. The reduction indicates improved functioning of kidney. The result requires further study taking a group of patients with >1.2 mean serum creatinine. If results are confirmed again, this might lead to a treatment for kidney patients.

There was marked improvement in hair loss and hair thinness for scalp psoriasis patients .Many patients reported re growth of hair on bald patches.

Improvements were noticed in HDL/LDL ratio.

Some obese patients saw reduction in their weights.

Conclusion

Psorcure Treatment Plan is faster in clearing the skin from psoriasis and restoration of immunity levels with better management of flare ups and rebounds and no significant side effect are some of the major benefits which one can draw from this treatment plan.

Psorcure Treatment Plan

The treatment plan developed by Dr. S Dhawan is a combination of

External Applications

Internal Medications

Dietary Management

Specially designed Yoga Exercises.

All the applications and medications are totally herbal and are prepared as per WHO guidelines for herbal Medicines. Accordingly no synthetic or chemically defined active substance have been added in finished product like (steroids and methotrexate ) and all the herbal Medicines contain only active ingredients present in plants. All the medicines, its constituents, the formulation, and the herbs used in Psorcure Treatment Plan are approved by Director of Ayurveda and siddha, Ministry of Health and family Welfare ,Government of India


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Jan01
Theory by Lead Researcher Gives New Hope for Permanent Cure of Psoriatic Conditions
Theory by Lead Researcher
Theory by Lead Researcher Gives New Hope for Permanent Cure of Psoriatic Conditions

(PRWEB) July 25, 2005 -- Defective bone marrow is the critical link for the psoriatic conditions, claims the lead researcher Dr. S Dhawan in his latest article titled, "Chronic Psoriasis – causes and treatment A new hope for permanent cure.

" Bone marrow is the production center of T Cells and in Psoriatic conditions these T Cells attack our own skin cells as if they are antigen presenting cells (APC) or alien toxins. This over burden leads to accelerated cell formation. The defective bone marrow changes the behavior of T Cells.

According to Ayurvedic texts, nature has given us a very efficient and powerful system of energy generation in our body. The process of this energy generation system (EGS) starts when we intake food, liquids etc. and it ends at formation of immunity (called Ojja in aurvedic text books).

The entire process got 8 stages.

1. In the digestion process, food gets converted into Rasa Dhatu.
2.From rasa dhatu develops RAKATA(Blood).
3. From rakta develops MASA(muscles).
4. From masa develops MEDA(fat).
5. From meda develops ASTHI(Bones).
6. From asthi develops MAJJA(Bone marrow).
7. From majja develops SHUKRA(semen).
8. From Semen develops the OJJA (Immunity)
Ayurvedic texts has mentioned that it takes 90 days for food to get converted into Shukra (Semen), and another 60 days from Shukra to Ojja (Immunity). Where any of the above stages are not functioning properly (for example leakage in intestine) or food as input is contaminated or contains opposite properties or is not digested properly in the first place, it produces all kind of problems in the body. For example instead of producing Rasa Dhatu during digestion process, the system will produces Ama Rasa (toxins or macro globules) . With this every other stage also gets contaminated. For example next stage produces Ama Rakta then Ama Masa, Ama Meda, Ama Asthi, Ama Majja, Ama Shukra and finally Ama Oaj. Improper digestion leads to ama majja (defective bone marrow ). Bone marrow is the production center for T cells. (Can you see the chain and main cause for psoriasis?). The validation study conducted in our clinic also confirms the results of this theory. A total of 968 patients were taken for this validation study. The distribution pattern was wide and dispersed with regard to age, gender and type of psoriatic conditions. All the patients were studied with regard to formation of psoriatic conditions, their food habits, working conditions and family conditions. Following conclusions were drawn from this study.

#1. A total of 80% of patients had problem of indigestion/constipation

In 25% of patients indigestion/constipation was the major trigger for flare-ups and severe psoriatic conditions. This is #2 trigger after stress (35% of patients).

18% of patients had the family history of Psoriasis but severity of psoriasis has no relation with family history.

Medical Research on the Intestine/Psoriasis Connection:

It is interesting to note here that scientists have long recognized that toxins leaking from the intestines are involved in psoriasis. The technical term for leaky intestines is called "intestinal permeability." Several researchers have written on this subject in the medical journals. Psoriasis is an autoimmune disorder and production of Ama Oaj is an indication of immunodeficiency. To cure any psoriatic patient permanently it is important to control all the stages of energy generation system of body so that all the 7 Dhatus from food (rakat,masa,meda,asthi,majja,shukra and oaj ) are produced in their purest form. By curing Ama majja (defective bone marrow) we are treating the patients at immunity levels. By producing pure Ojja, we are making patients immune to psoriasis triggers. "12 years back when I took psoriasis as my subject for research," says Dr. S Dhawan in his article, "I was also caught into the dilemma of following perception which most of the scientific community carries around the world."

"Psoriasis is a skin disease which appears in 2-4% of the population. The cause of this chronic skin disease is unknown. Research has proven that psoriasis is an auto-immune disease, and not long ago the psoriasis gene(s) were found. The disease, or the tendency to get it, is inherited. It is possible to have psoriasis without any visible symptoms. This makes research on it quite complicated."

Being the firm believer of Ayurveda and its treatments methods, I took Ayurveda and its text books as the basis of my research work. During the 10 years of my research I delicately correlated the information gathered by the scientific community on symptoms and triggers for various psoriasis ailments and symptoms and causes given in ayurvedic text books. Finally I was able to form a complete chain leading to psoriatic conditions. I developed treatment method based on this theory and treating my patients for the last three years.

Treatment Method

We can divide our treatment method primarily into 3 major segments

Working on Hyperkeratosis (fast cell division) – External Treatment
Working on APC(Antigen Presenting cells ) – Internal Treatment
Working on Major triggers – Stress, Indigestion/constipation

This treatment method is totally herbal based with no known side effects. Various studies have been conducted which confirmed the strength of medicinal formulations administered under this treatment method The effectiveness or efficacy of this treatment method is evident from the vary fact that there are more that 1500 patients treated with this method during the last 3 years and none has reported reappearance of psoriatic conditions after the completion of treatment period. This success story is growing every day with more patients getting cured permanently.


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Jan01
New hope for chronic psoriasis patients
New Hope for Chronic Psoriatic Patients
Psorcure Oil can treat chronic psoriasis disease with no re-occurrence of lesions – a major breakthrough in Psoriasis Treatment.

Clinical trial showed that Psorcure Oil is much more effective than calcipotriol in stopping the lesions to reappear after the treatment.

Psorcure Oil is part of treatment plan developed by Dr S Dhawan to cure Psoriatic patients permanently. Psorcure Oil is a specially formulated extracts of herbs optimized to treat psoriatic patients.

To reduce scales in Psoriatic Patients, most of the Dermatologists recommend and prefer to use the Vitamin D3 analog (calcipotriol) as an external application. This application also helps inhibiting T cell proliferation.

A 6 week clinic trial was conducted to compare the effectiveness of Psorcure Oil and Calcipotriol. For this purpose 25 chronic plaque psoriatic patients were selected from the list of volunteers who offered themselves for this trial. The selection was made based on redness; scales level and PASI score to maintain the uniformity in severity of patients selected for trial. Average PASI score was determined separately for left side and right side of every patient’s body. The score was 20.1 and 20.3 respectively.

Patients mix was widely distributed. Out of 25 patients, 14 patients were male and 11 were females. All the patients were in the age group of 6years to 65 years.

Every patient was tested for Biochemical and Hematological investigations before and after trial period. The investigations include Whole blood count, Total calcium and phosphate, alkaline phosphate, Total proteins and creatanin levels.

Trial Methodology

During the trial period, every patient was given calcipotriol ointment to apply on the right side of the body and psorcure oil to apply on the left side of the body. After application of Oil, left part of body for every patient was exposed to sun light for 15 minutes as part of treatment.

During the trial period no patient was allowed to take any other treatment, application, calcium supplements or any other oral or topical psoriatic therapy. Further no internal medication was given to any of the patients during trial period.

Trial Results

Out of 25 patients 3 patients defaulted, 2 patients developed worsened with calcipotriol and one patient developed rashes with psorcure oil.

The PASI score after 6 weeks trial period

Calcipotriol group 3.8 (A reduction of 87% in PASI Score)

Psorcure Oil Group 2.8 (A reduction of 90% in PASI Score)

After the end of 3 months observation period

Calcipotriol group Lesions reappeared in 50% of cases

Psorcure Oil Group Lesions reappeared in only 5% of cases.

Conclusion

Psorcure Oil is more effective for longer remission periods and relief. In combination with other medicines it helps curing psoriasis permanently.

Dr. S Dhawan has dedicated his life for the research and treatment of psoriasis. During his long research he formed a theory on the causes of psoriasis and based on this theory he developed a herbal based specially formulated treatment plan to cure psoriatic conditions. Any one can read his theory at http://clinicpsoriasis.com/ayurvedic-science.asp

He has treated more than 1500 patients with his new treatment plan during the last 3 years. He monitors the conditions of all his patients even after completion of treatment period. Not even a single patient has reported any major reappearance of psoriatic conditions after getting cured. You can see complete analysis of his patient’s register at http://clinicpsoriasis.com/patient-analysis.asp

An observation period of 3 years is not enough to claim that my treatment provides total cure, says Dr. S Dhawan, but no major reappearance of psoriasis in any of my patients under my treatment is the longest remission period observed ever under any treatment plan available in the world. This in itself is a remarkable achievement in psoriasis treatment quest.

Dr. Dhawan is available for free consultation at www.vedawave.com


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Dec21
diabetic retinopathy (IJO-98)
Diabetes mellitus is on the increase and seems to be emerging as a major public health problem for our country. Interestingly, for every patient who is known to have diabetes, another has the disease but is unaware of it. It is a multisystem disorder, including cardiovascular disease, renal failure, peripheral neuropathy, and retinopathy which may lead to blindness. The relationship of diabetes mellitus and retinopathy is most interesting. It has been reported in the literature from the developed world that 20 years after the onset of diabetes, nearly all patients with type I diabetes (insulin-dependent) and more than 60% of those with type II diabetes (non-insulin dependent) will have some degree of retinopathy. However, this also depends on the degree of metabolic control of diabetes.

Diabetic retinopathy is a leading cause of blindness amongst the working class (<55 years old) in the industrialized countries. The emerging scenario in the developing world suggests that diabetes and blindness secondary to diabetic retinopathy may soon be a major problem in this part of the world as well. Unfortunately, India has no figures for diabetic retinopathy as a cause for blindness as no proper survey has been carried out as yet. Our blindness figures still rest on the decade-old National Programme for Control of Blindness survey carried out in the mid-eighties.

Screening for diabetic retinopathy should be mandatory for all diabetics as diabetes mellitus is now assuming alarming epidemic proportions in the developing countries due to an increasingly inappropriate diet high in fat and carbohydrates, sedentary life styles, and obesity. Hence, screening for retinopathy is important. This should consist of dilated fundus examination of the diabetics at least once a year. This could best be achieved by a National Diabetic Retinopathy Screening Programme. Basic requirements for such a screening programme include identification of the population at risk, an efficient recall system so that patients are not lost to follow-up, an effective instrument for retinal viewing (an ophthalmoscope or a non-mydriatic fundus camera), an experienced interpreter of the findings, a screening protocol defining clinical parameters for referral and treatment, a system for effective management of the identified cases and their feedback, and finally, quality control.

Information obtained from various randomized control trials such as Diabetes Control and Complication Trial,[2] Diabetic Retinopathy Study,[3] Early Treatment of Diabetic Retinopathy Study,[4] and Diabetes Retinopathy Vitrectomy Study[5] are valuable both from overall health planning and individual treatment points of view. Good glycemic control can markedly reduce the retinopathy in patients with type I diabetes. Timely laser surgery can reduce risk of visual loss from proliferative diabetic retinopathy by 90%. Timely laser for diabetic macular edema can reduce the risk of moderate visual loss by 50%. Vitrectomy surgery may restore useful vision when retinopathy is too advanced for laser treatment.

Handling of the increasing problem of diabetes mellitus and its danger to sight should also include effective education and communication with the patients on the one hand, and with general ophthalmologists, primary care physicians, diabetologists, and allied health professionals on the other hand.

Dr Amol Wankhede
Retina eye centre, Nasik


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